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Molecular Biology

D-Index
55
Citations
13159
World Ranking
2261
National Ranking
56

Overview

Thomas J. Gonda is affiliated with the University of South Australia in Australia. Their research primarily focuses on biochemistry, genetics, and molecular biology, with significant contributions to medicine. The scientist's work spans several subfields including molecular biology, hematology, oncology, cancer research, and genetics.

The main topics covered by their research include:

  • Acute Myeloid Leukemia Research
  • Cancer-related Molecular Pathways
  • RNA modifications and cancer
  • Epigenetics and DNA Methylation
  • Cancer Genomics and Diagnostics
  • Ubiquitin and proteasome pathways
  • Histone Deacetylase Inhibitors Research

Thomas J. Gonda has published in a variety of scientific venues, with multiple papers appearing in prestigious journals and platforms, including:

  • Nature Communications
  • Blood
  • Cell Reports
  • Oncogene
  • bioRxiv (Cold Spring Harbor Laboratory)

Their recent papers reflect ongoing research interests and contributions to hematology and cancer fields. Notable papers include:

  • "Nuclear stabilization of p53 requires a functional nucleolar surveillance pathway," 2022, Cell Reports
  • "C/EBPβ is a MYB- and p300-cooperating pro-leukemogenic factor and promising drug target in acute myeloid leukemia," 2021, Oncogene
  • "Germline mutations in mitochondrial complex I reveal genetic and targetable vulnerability in IDH1-mutant acute myeloid leukaemia," 2022, Nature Communications
  • "Childhood acute myeloid leukemia shows a high level of germline predisposition," 2021, Blood
  • "Nuclear stabilisation of p53 requires a functional nucleolar surveillance pathway," 2021, bioRxiv (Cold Spring Harbor Laboratory)

Thomas J. Gonda has collaborated frequently with a select group of co-authors, reflecting sustained research partnerships. The most frequent co-authors include:

  • Débora A. Casolari
  • Richard J. D'Andrea
  • Saumya E. Samaraweera
  • Paul Leo
  • Kyaw Ze Ya Maung

Best Publications

  • A family of cytokine-inducible inhibitors of signalling

    Robyn Starr;Tracy A. Willson;Elizabeth M. Viney;Leecia J. L. Murray

  • MYB function in normal and cancer cells.

    Robert G. Ramsay;Thomas J. Gonda

  • Delineation of three functional domains of the transcriptional activator encoded by the c-myb protooncogene

    Hiroshi Sakura;Chie Kanei-Ishii;Takahiro Nagase;Hideki Nakagoshi

  • A lethal myeloproliferative syndrome in mice transplanted with bone marrow cells infected with a retrovirus expressing granulocyte-macrophage colony stimulating factor.

    G. R. Johnson;T. J. Gonda;D. Metcalf;I. K. Hariharan

  • PG545, a dual heparanase and angiogenesis inhibitor, induces potent anti-tumour and anti-metastatic efficacy in preclinical models

    K Dredge;E Hammond;P Handley;T J Gonda

  • Role and potential for therapeutic targeting of MYB in leukemia.

    D R Pattabiraman;T J Gonda

  • Mechanism of and requirement for estrogen-regulated MYB expression in estrogen-receptor-positive breast cancer cells.

    Yvette Drabsch;Honor Hugo;Rui Zhang;Dennis H. Dowhan

  • Comparison of expression in hemopoietic cells by retroviral vectors carrying two genes.

    D. D. L. Bowtell;S. Cory;G. R. Johnson;T. J. Gonda

  • Directly targeting transcriptional dysregulation in cancer

    Thomas J. Gonda;Robert G. Ramsay

  • Molecular Cloning Reveals that the p160 Myb-Binding Protein Is a Novel, Predominantly Nucleolar Protein Which May Play a Role in Transactivation by Myb

    Fiona J. Tavner;Richard Simpson;Shigeki Tashiro;Diane Favier

  • Activation of c-myb by carboxy-terminal truncation: relationship to transformation of murine haemopoietic cells in vitro.

    T J Gonda;C Buckmaster;R G Ramsay

  • The PG500 series: novel heparan sulfate mimetics as potent angiogenesis and heparanase inhibitors for cancer therapy

    Keith Dredge;Edward Hammond;Kat Davis;Cai Ping Li

  • Interaction of c-Myb with p300 is required for the induction of acute myeloid leukemia (AML) by human AML oncogenes

    Diwakar R. Pattabiraman;Crystal McGirr;Konstantin Shakhbazov;Valerie Barbier

  • Activating point mutations in the common beta subunit of the human GM-CSF, IL-3 and IL-5 receptors suggest the involvement of beta subunit dimerization and cell type-specific molecules in signalling.

    B. J. Jenkins;R. D'Andrea;T. J. Gonda

  • Negative autoregulation of c-Myb activity by homodimer formation through the leucine zipper.

    T Nomura;N Sakai;A Sarai;T Sudo

  • Myb expression is higher in malignant human colonic carcinoma and premalignant adenomatous polyps than in normal mucosa.

    R G Ramsay;M A Thompson;J A Hayman;G Reid

  • Integrated genome-wide chromatin occupancy and expression analyses identify key myeloid pro-differentiation transcription factors repressed by Myb

    Liang Zhao;Evgeny A. Glazov;Diwakar R. Pattabiraman;Faisal Al-Owaidi

  • Targeting c-Myb expression in human disease

    Robert G Ramsay;Anna L Barton;Thomas J Gonda

  • The use of hybridization analysis with complementary DNA to determine the RNA sequence homology between strains of plant viruses: its application to several strains of cucumoviruses.

    Thomas J. Gonda;Robert H. Symons

  • Long-term exposure to retrovirally expressed granulocyte-colony-stimulating factor induces a nonneoplastic granulocytic and progenitor cell hyperplasia without tissue damage in mice.

    Juliana M. Chang;Donald Metcalf;Thomas J. Gonda;Gregory R. Johnson

Frequent Co-Authors

Robert G. Ramsay
Robert G. Ramsay Peter MacCallum Cancer Centre
Brian Gabrielli
Brian Gabrielli University of Queensland
Brendan J. Jenkins
Brendan J. Jenkins Hudson Institute of Medical Research
Andrew C. Perkins
Andrew C. Perkins Monash University
Erik W. Thompson
Erik W. Thompson Queensland University of Technology
Angel F. Lopez
Angel F. Lopez University of South Australia
Leonie K. Ashman
Leonie K. Ashman University of Newcastle Australia
Emma L. Duncan
Emma L. Duncan University of Queensland
Matthew A. Brown
Matthew A. Brown Guy's and St Thomas' NHS Foundation Trust

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