Leonie K. Ashman

Overview

Best Publications

• The biology of stem cell factor and its receptor C-kit.

  Leonie K Ashman

  823
  Citations

• Juxtamembrane mutant V560GKit is more sensitive to Imatinib (STI571) compared with wild-type c-kit whereas the kinase domain mutant D816VKit is resistant.

  Michelle J. Frost;Petranel T. Ferrao;Timothy P. Hughes;Leonie K. Ashman

  369
  Citations

• Regulation of Endothelial Cell Motility by Complexes of Tetraspan Molecules CD81/TAPA-1 and CD151/PETA-3 with α3β1 Integrin Localized at Endothelial Lateral Junctions

  María Yáñez-Mó;Arántzazu Alfranca;Carlos Cabañas;Mónica Marazuela

  334
  Citations

• Mast cell typing: demonstration of a distinct hematopoietic cell type and evidence for immunophenotypic relationship to mononuclear phagocytes.

  P Valent;LK Ashman;W Hinterberger;F Eckersberger

  304
  Citations

• Recombinant human stem cell factor stimulates differentiation of mast cells from dispersed human fetal liver cells

  Anne-Marie A. Irani;Gunnar Nilsson;Ulla Miettinen;Shirley S. Craig

  295
  Citations

• A comparative study of the phenotype and proliferative capacity of peripheral blood (PB) CD34+ cells mobilized by four different protocols and those of steady-phase PB and bone marrow CD34+ cells

  LB To;DN Haylock;T Dowse;PJ Simmons

  275
  Citations

• Expression of the YB5.B8 antigen (c-kit proto-oncogene product) in normal human bone marrow

  LK Ashman;AC Cambareri;LB To;RJ Levinsky

  273
  Citations

• Localization of the Transmembrane 4 Superfamily (TM4SF) Member PETA-3 (CD151) in Normal Human Tissues: Comparison with CD9, CD63, and α5β1 Integrin:

  Paul M. Sincock;Graham Mayrhofer;Leonie K. Ashman

  272
  Citations

• PETA-3/CD151, a member of the transmembrane 4 superfamily, is localised to the plasma membrane and endocytic system of endothelial cells, associates with multiple integrins and modulates cell function

  P.M. Sincock;S. Fitter;R.G. Parton;M.C. Berndt

  253
  Citations

• Biotinylation: an alternative to radioiodination for the identification of cell surface antigens in immunoprecipitates.

  S.R. Cole;L.K. Ashman;P.L. Ey

  241
  Citations

• Monoclonal antibody YB5.B8 identifies the human c-kit protein product

  Norma B. Lerner;Karl H. Nocka;Stephen R. Cole;Feihua Qiu

  235
  Citations

• Characterization of mice lacking the tetraspanin superfamily member CD151.

  Mark D Wright;Sean Geary;Stephen Fitter;Gregory William Moseley

  231
  Citations

• α3β1 integrin–CD151, a component of the cadherin–catenin complex, regulates PTPμ expression and cell–cell adhesion

  Nibedita Chattopadhyay;Zemin Wang;Zemin Wang;Leonie K. Ashman;Susann M. Brady-Kalnay

  216
  Citations

• Expression of a functional c-kit receptor on a subset of natural killer cells.

  M E Matos;G S Schnier;M S Beecher;L K Ashman

  194
  Citations

• A Critical Role for Tetraspanin CD151 in α3β1 and α6β4 Integrin–dependent Tumor Cell Functions on Laminin-5

  Nicole E. Winterwood;Afshin Varzavand;Marit N. Meland;Leonie K. Ashman

  190
  Citations

• Therapeutic targeting of c-KIT in cancer

  Leonie K Ashman;Renate Griffith

  184
  Citations

• Multiple levels of interactions within the tetraspanin web.

  Stéphanie Charrin;Serge Manié;Martine Billard;Leonie Ashman

  175
  Citations

• Colocalization of the tetraspanins, CO-029 and CD151, with integrins in human pancreatic adenocarcinoma: impact on cell motility

  Sabine Gesierich;Claudia Paret;Dagmar Hildebrand;Jürgen Weitz

  166
  Citations

• Phosphatidylinositol 3 kinase contributes to the transformation of hematopoietic cells by the D816V c-Kit mutant.

  RuJu Chian;Sonia Young;Alla Danilkovitch-Miagkova;Lars Rönnstrand

  165
  Citations

• Transmembrane 4 superfamily protein CD151 (PETA-3) associates with beta 1 and alpha IIb beta 3 integrins in haemopoietic cell lines and modulates cell-cell adhesion.

  Stephen Fitter;Paul M. Sincock;Corina N. Jolliffe;Leonie K. Ashman

  161
  Citations