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Eric Rubinstein

Eric Rubinstein

D-Index & Metrics

Biology and Biochemistry

D-Index
66
Citations
17075
World Ranking
8591
National Ranking
295

Research.com Recognitions

  • 1985 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Genetics

His primary scientific interests are in Cell biology, Tetraspanin, CD81, Integrin and Membrane protein. Eric Rubinstein has researched Cell biology in several fields, including Transmembrane domain and Transmembrane protein. His study on CD82 is often connected to APH-1 as part of broader study in Tetraspanin.

His CD81 research is multidisciplinary, incorporating perspectives in Molecular biology, Digitonin, CD151 and Circumsporozoite protein. His Integrin research focuses on Transfection and how it relates to Raji cell, Fibronectin, Laminin, HLA-DR and Antigen-presenting cell. He is studying Integral membrane protein, which is a component of Membrane protein.

His most cited work include:

  • Severely Reduced Female Fertility in CD9-Deficient Mice (531 citations)
  • The tetraspanin CD63 regulates ESCRT-independent and -dependent endosomal sorting during melanogenesis. (412 citations)
  • CD9, CD63, CD81, and CD82 are components of a surface tetraspan network connected to HLA-DR and VLA integrins (339 citations)

What are the main themes of his work throughout his whole career to date?

Cell biology, Tetraspanin, CD81, Molecular biology and Integrin are his primary areas of study. Eric Rubinstein studied Cell biology and Transmembrane protein that intersect with Signal transduction. His Tetraspanin research is multidisciplinary, incorporating elements of Plasma protein binding, Cell migration, Membrane protein and Cancer research.

His research investigates the connection between CD81 and topics such as Receptor that intersect with issues in Intracellular and Immunology. The various areas that he examines in his Molecular biology study include Cell culture, Antigen, Platelet activation and Antibody, Monoclonal antibody. His work is dedicated to discovering how Integrin, Transmembrane domain are connected with Digitonin and Compartmentalization and other disciplines.

He most often published in these fields:

  • Cell biology (77.84%)
  • Tetraspanin (78.44%)
  • CD81 (44.31%)

What were the highlights of his more recent work (between 2016-2020)?

  • Cell biology (77.84%)
  • Tetraspanin (78.44%)
  • Notch signaling pathway (12.57%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Cell biology, Tetraspanin, Notch signaling pathway, CD81 and Receptor. While working on this project, Eric Rubinstein studies both Cell biology and ADAM10. Eric Rubinstein has included themes like Cancer research, Cell migration, Gene knockdown, T cell and Monoclonal antibody in his Tetraspanin study.

His biological study deals with issues like Endoplasmic reticulum, which deal with fields such as Tissue homeostasis, Signal transduction, Molecular biology, Transfection and Cell culture. His studies examine the connections between CD81 and genetics, as well as such issues in Membrane, with regards to Viral protein, Flow cytometry, Viral replication and Budding. Eric Rubinstein works mostly in the field of Receptor, limiting it down to concerns involving Virology and, occasionally, Plasmodium and Malaria.

Between 2016 and 2020, his most popular works were:

  • Structural Basis for Regulated Proteolysis by the α-Secretase ADAM10 (63 citations)
  • Plasmodium P36 determines host cell receptor usage during sporozoite invasion (40 citations)
  • Plasmodium P36 determines host cell receptor usage during sporozoite invasion (40 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Genetics

His primary scientific interests are in Cell biology, Notch signaling pathway, Tetraspanin, ADAM10 and Ectodomain. Eric Rubinstein interconnects Endocytosis and WW domain in the investigation of issues within Cell biology. His study in Endocytosis is interdisciplinary in nature, drawing from both T cell, Immune system, Antigen presentation, Antigen and Endosome.

His work deals with themes such as Phenotype, Cancer research and CD44, which intersect with Tetraspanin. His study of ADAM10 brings together topics like Membrane protein, Cell adhesion molecule, Amyloid precursor protein secretase and Proteolysis. His Intracellular research incorporates themes from Extracellular, Internalization and Notch proteins.

Best Publications

  • The tetraspanin CD63 regulates ESCRT-independent and -dependent endosomal sorting during melanogenesis.

    Guillaume van Niel;Guillaume van Niel;Stéphanie Charrin;Sabrina Simoes;Sabrina Simoes;Maryse Romao;Maryse Romao

  • Severely Reduced Female Fertility in CD9-Deficient Mice

    François Le Naour;Eric Rubinstein;Claude Jasmin;Michel Prenant

  • Lateral organization of membrane proteins: tetraspanins spin their web.

    Stéphanie Charrin;Stéphanie Charrin;François le Naour;François le Naour;Olivier Silvie;Olivier Silvie;Pierre-Emmanuel Milhiet;Pierre-Emmanuel Milhiet

  • Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9.

    Mathilde Mathieu;Mathilde Mathieu;Nathalie Névo;Mabel Jouve;José Ignacio Valenzuela

  • CD9, CD63, CD81, and CD82 are components of a surface tetraspan network connected to HLA-DR and VLA integrins

    Eric Rubinstein;François Le Naour;Cécile Lagaudrière-Gesbert;Martine Billard

  • Tetraspanins at a glance

    Stéphanie Charrin;Stéphanie Jouannet;Claude Boucheix;Eric Rubinstein

  • Blood diffusion and Th1-suppressive effects of galectin-9-containing exosomes released by Epstein-Barr virus-infected nasopharyngeal carcinoma cells.

    Jihène Klibi;Toshiro Niki;Alexander Riedel;Catherine Pioche-Durieu

  • A role for apical membrane antigen 1 during invasion of hepatocytes by Plasmodium falciparum sporozoites.

    Olivier Silvie;Jean-François Franetich;Stéphanie Charrin;Markus S. Mueller

  • A role for exosomes in the constitutive and stimulus-induced ectodomain cleavage of L1 and CD44

    Alexander Stoeck;Sascha Keller;Svenja Riedle;Michael P. Sanderson

  • The major CD9 and CD81 molecular partner. Identification and characterization of the complexes.

    Stéphanie Charrin;François Le Naour;Michael Oualid;Martine Billard

  • Selective tetraspan-integrin complexes (CD81/alpha4beta1, CD151/alpha3beta1, CD151/alpha6beta1) under conditions disrupting tetraspan interactions.

    Serru;Le Naour F;Billard M;Azorsa Do

  • Differential stability of tetraspanin/tetraspanin interactions: role of palmitoylation

    Stéphanie Charrin;Serge Manié;Michael Oualid;Martine Billard

  • A physical and functional link between cholesterol and tetraspanins

    Stéphanie Charrin;Serge Manié;Christoph Thiele;Martine Billard

  • Reduced fertility of female mice lacking CD81.

    Eric Rubinstein;Ahmed Ziyyat;Michel Prenant;Edyta Wrobel

  • EWI-2 and EWI-F Link the Tetraspanin Web to the Actin Cytoskeleton through Their Direct Association with Ezrin-Radixin-Moesin Proteins

    Mónica Sala-Valdés;Ángeles Ursa;Stéphanie Charrin;Eric Rubinstein

  • Profiling of the Tetraspanin Web of Human Colon Cancer Cells

    François Le Naour;Magali André;Céline Greco;Martine Billard

  • Tetraspanins and malignancy.

    Claude Boucheix;Guy Huynh Thien Duc;Claude Jasmin;Eric Rubinstein

  • The molecular players of sperm–egg fusion in mammals

    Eric Rubinstein;Ahmed Ziyyat;Jean-Philippe Wolf;François Le Naour

  • EWI-2 is a new component of the tetraspanin web in hepatocytes and lymphoid cells.

    Stéphanie Charrin;François Le Naour;Valérie Labas;Martine Billard

  • CD9 antigen is an accessory subunit of the VLA integrin complexes

    Eric Rubinstein;François le Naour;Martine Billard;Michel Prenant

Frequent Co-Authors

Claude Boucheix
Claude Boucheix University of Paris-Saclay
Dominique Mazier
Dominique Mazier Sorbonne University
Shoshana Levy
Shoshana Levy Stanford University
Francisco Sánchez-Madrid
Francisco Sánchez-Madrid Autonomous University of Madrid
Thomas F. Baumert
Thomas F. Baumert University of Strasbourg
François Lanza
François Lanza University of Strasbourg
Mirjam B. Zeisel
Mirjam B. Zeisel University of Strasbourg
María Yáñez-Mó
María Yáñez-Mó Spanish National Research Council
Robert W. Sauerwein
Robert W. Sauerwein Radboud University
François Nosten
François Nosten MORU Mahidol Oxford Tropical Medicine Research Unit

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