Michael F. McDermott

What is he best known for?

The fields of study he is best known for:

• Gene
• Internal medicine
• Inflammation

Michael F. McDermott mostly deals with Immunology, Familial Cold Autoinflammatory Syndrome, Inflammation, Cryopyrin-associated periodic syndrome and Tumor necrosis factor alpha. His work carried out in the field of Immunology brings together such families of science as Disease and Muckle–Wells syndrome. His work in Disease covers topics such as Receptor which are related to areas like Autoantibody.

His research in Inflammation intersects with topics in Acquired immune system, Autoimmunity and Autoinflammatory Disorders. His Cryopyrin-associated periodic syndrome research includes themes of NALP3 and Autoinflammatory Syndrome. His work is dedicated to discovering how Rheumatoid arthritis, Arthritis are connected with HLA-B Antigens, Cytokine and Signal transduction and other disciplines.

His most cited work include:

• NALP3 Forms an IL-1β-Processing Inflammasome with Increased Activity in Muckle-Wells Autoinflammatory Disorder (1324 citations)
• GERMLINE MUTATIONS IN THE EXTRACELLULAR DOMAINS OF THE 55 KDA TNF RECEPTOR, TNFR1, DEFINE A FAMILY OF DOMINANTLY INHERITED AUTOINFLAMMATORY SYNDROMES (1030 citations)
• Cytokine gene polymorphism in human disease: on-line databases. (748 citations)

What are the main themes of his work throughout his whole career to date?

Michael F. McDermott mainly investigates Immunology, Inflammation, Disease, Tumor necrosis factor alpha and Internal medicine. As part of one scientific family, he deals mainly with the area of Immunology, narrowing it down to issues related to the Familial Mediterranean fever, and often MEFV and Genetics. His Inflammation research is multidisciplinary, relying on both Cystic fibrosis and Cystic fibrosis transmembrane conductance regulator.

His Disease research is multidisciplinary, incorporating perspectives in Pyrin domain and Bioinformatics. Michael F. McDermott combines subjects such as Receptor, Unfolded protein response, Cytokine and Molecular biology with his study of Tumor necrosis factor alpha. His studies deal with areas such as Gastroenterology, Endocrinology and Circulating MicroRNA as well as Internal medicine.

He most often published in these fields:

• Immunology (59.90%)
• Inflammation (28.93%)
• Disease (22.34%)

What were the highlights of his more recent work (between 2017-2021)?

• Inflammation (28.93%)
• Cystic fibrosis (14.72%)
• Immunology (59.90%)

In recent papers he was focusing on the following fields of study:

Inflammation, Cystic fibrosis, Immunology, Proinflammatory cytokine and Innate immune system are his primary areas of study. His Inflammation research is multidisciplinary, relying on both Pathogenesis and Cystic fibrosis transmembrane conductance regulator. His Immunology study frequently intersects with other fields, such as Genotype.

His studies in Proinflammatory cytokine integrate themes in fields like Secretion, Downregulation and upregulation, Cell biology, Unfolded protein response and Lumacaftor. The Innate immune system study which covers Immunodeficiency that intersects with Haploinsufficiency and Autoinflammatory Syndrome. In his study, Receptor, Rheumatoid arthritis, Cytokine, Interleukin 6 and Overproduction is inextricably linked to Tumor necrosis factor alpha, which falls within the broad field of Immune system.

Between 2017 and 2021, his most popular works were:

• Tumour necrosis factor signalling in health and disease (43 citations)
• Tumour necrosis factor signalling in health and disease (43 citations)
• ENaC-mediated sodium influx exacerbates NLRP3-dependent inflammation in cystic fibrosis. (26 citations)

In his most recent research, the most cited papers focused on:

• Gene
• Internal medicine
• Inflammation

Michael F. McDermott spends much of his time researching Proinflammatory cytokine, Inflammation, Tumor necrosis factor alpha, Innate immune system and Unfolded protein response. Michael F. McDermott interconnects Downregulation and upregulation and Cystic fibrosis, Cystic fibrosis transmembrane conductance regulator in the investigation of issues within Proinflammatory cytokine. His study focuses on the intersection of Downregulation and upregulation and fields such as Endocrinology with connections in the field of Inflammasome.

Inflammasome is a subfield of Immunology that Michael F. McDermott studies. His Tumor necrosis factor alpha study combines topics in areas such as Receptor and Cytokine. His Innate immune system study deals with Disease intersecting with Neuroscience.