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Overview

Marco Gattorno is affiliated with the Istituto Giannina Gaslini in Italy. Their research spans several interconnected fields, focusing on medicine and biochemistry, genetics, and molecular biology. The subfields mainly addressed include immunology, molecular biology, rheumatology, hematology, and surgery.

Gattorno's work covers a range of topics within immunology and inflammatory diseases. Key areas of focus include inflammasome and immune disorders, autoimmune and inflammatory disorders research, immunodeficiency and autoimmune disorders, Kawasaki disease and coronary complications, systemic lupus erythematosus research, interferon and immune responses, and IL-33, ST2, and ILC pathways.

Recent papers reflect an interest in both clinical and mechanistic aspects of immune responses and autoinflammatory diseases. Notable publications include:

  • "On the Alert for Cytokine Storm: Immunopathology in COVID-19" (2020) published in Arthritis & Rheumatology
  • "Overview of STING-Associated Vasculopathy with Onset in Infancy (SAVI) Among 21 Patients" (2020) published in The Journal of Allergy and Clinical Immunology In Practice
  • "Effect of anakinra on mortality in patients with COVID-19: a systematic review and patient-level meta-analysis" (2021) published in The Lancet Rheumatology
  • "Safety and efficacy of early high-dose IV anakinra in severe COVID-19 lung disease" (2020) published in Journal of Allergy and Clinical Immunology
  • "The 2021 EULAR/American College of Rheumatology points to consider for diagnosis, management and monitoring of the interleukin-1 mediated autoinflammatory diseases: cryopyrin-associated periodic syndromes, tumour necrosis factor receptor-associated periodic syndrome, mevalonate kinase deficiency, and deficiency of the interleukin-1 receptor antagonist" (2022) published in Annals of the Rheumatic Diseases

Gattorno has collaborated frequently with several researchers, including Roberta Caorsi, Stefano Volpi, Riccardo Papa, Antonella Insalaco, and Seza Özen.

The most frequent publication venues for their work include Annals of the Rheumatic Diseases, Lara D. Veeken, Frontiers in Immunology, Pediatric Rheumatology, and Journal of Clinical Immunology.

Best Publications

  • Surface phenotype and antigenic specificity of human interleukin 17–producing T helper memory cells

    Eva V Acosta-Rodriguez;Laura Rivino;Jens Geginat;David Jarrossay

  • Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β.

    Christina E. Zielinski;Federico Mele;Dominik Aschenbrenner;David Jarrossay

  • On the Alert for Cytokine Storm: Immunopathology in COVID-19.

    Lauren A Henderson;Scott W Canna;Grant S Schulert;Stefano Volpi

  • EULAR recommendations for the management of familial Mediterranean fever

    Seza Ozen;Erkan Demirkaya;Burak Erer;Avi Livneh

  • Classification criteria for autoinflammatory recurrent fevers

    Marco Gattorno;Michael Hofer;Silvia Federici;Federica Vanoni

  • Canakinumab for the Treatment of Autoinflammatory Recurrent Fever Syndromes

    Fabrizio De Benedetti;Marco Gattorno;Jordi Anton;Eldad Ben-Chetrit

  • Treatment of autoinflammatory diseases: results from the Eurofever Registry and a literature review

    Nienke Ter Haar;Helen Lachmann;Seza Özen;Pat Woo

  • OLT1177, a β-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation.

    Carlo Marchetti;Benjamin Swartzwelter;Fabia Gamboni;Charles P. Neff

  • The pattern of response to anti-interleukin-1 treatment distinguishes two subsets of patients with systemic-onset juvenile idiopathic arthritis.

    Marco Gattorno;Alessandra Piccini;Denise Lasigliè;Sara Tassi

  • Coexpression of CD25 and CD27 identifies FoxP3+ regulatory T cells in inflamed synovia.

    Claudia R. Ruprecht;Marco Gattorno;Francesca Ferlito;Andrea Gregorio

  • Clinical features, long-term follow-up and outcome of a large cohort of patients with Chronic Granulomatous Disease: an Italian multicenter study.

    Baldassarre Martire;Roberto Rondelli;Annarosa Soresina;Claudio Pignata

  • Bone marrow-derived mesenchymal stem cells induce both polyclonal expansion and differentiation of B cells isolated from healthy donors and systemic lupus erythematosus patients.

    Elisabetta Traggiai;Stefano Volpi;Francesca Schena;Marco Gattorno

  • Persistent efficacy of anakinra in patients with tumor necrosis factor receptor-associated periodic syndrome.

    M. Gattorno;M. A. Pelagatti;M. A. Pelagatti;A. Meini;L. Obici

  • The phenotype of TNF receptor-associated autoinflammatory syndrome (TRAPS) at presentation: a series of 158 cases from the Eurofever/EUROTRAPS international registry

    H. J. Lachmann;R. Papa;K. Gerhold;L. Obici

  • Evidence-based provisional clinical classification criteria for autoinflammatory periodic fevers

    Silvia Federici;Maria Pia Sormani;Seza Ozen;Helen J Lachmann

  • Effect of Anakinra on Recurrent Pericarditis Among Patients With Colchicine Resistance and Corticosteroid Dependence: The AIRTRIP Randomized Clinical Trial.

    Antonio Brucato;Massimo Imazio;Marco Gattorno;George Lazaros

  • Recommendations for the management of autoinflammatory diseases

    Nienke M ter Haar;Marlen Oswald;Jerold Jeyaratnam;Jordi Anton

  • Regulation of Human Macrophage M1-M2 Polarization Balance by Hypoxia and the Triggering Receptor Expressed on Myeloid Cells-1.

    Federica Raggi;Simone Pelassa;Daniele Pierobon;Federica Penco

  • Pattern of interleukin‐1β secretion in response to lipopolysaccharide and ATP before and after interleukin‐1 blockade in patients with CIAS1 mutations

    Marco Gattorno;Sara Tassi;Sonia Carta;Laura Delfino

  • Pediatric Antiphospholipid Syndrome: Clinical and Immunologic Features of 121 Patients in an International Registry

    Tadej Avčin;Rolando Cimaz;Earl D. Silverman;Ricard Cervera

Frequent Co-Authors

Alberto Martini
Alberto Martini University of Genoa
Isabella Ceccherini
Isabella Ceccherini University of Genoa
Helen J. Lachmann
Helen J. Lachmann University College London
Seza Ozen
Seza Ozen Hacettepe University
Angelo Ravelli
Angelo Ravelli University of Genoa
Nicolino Ruperto
Nicolino Ruperto Istituto Giannina Gaslini
Vito Pistoia
Vito Pistoia Boston Children's Hospital
Anna Simon
Anna Simon Christian Medical College & Hospital
Maria Pia Sormani
Maria Pia Sormani University of Genoa
Anna Rubartelli
Anna Rubartelli National Cancer Research Institute, UK

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