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D-Index & Metrics

Biology and Biochemistry

D-Index
70
Citations
23873
World Ranking
6882
National Ranking
524

Overview

Anna Rubartelli is affiliated with the National Cancer Research Institute, UK, based in the United Kingdom. Their research spans multiple fields including Medicine, Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology. They have contributed notably to subfields such as Molecular Biology, Immunology, Surgery, Cell Biology, and Physiology.

The research topics Anna Rubartelli has worked on encompass areas such as inflammasome and immune disorders, hernia repair and management, advanced glycation end products research, endoplasmic reticulum stress and disease, abdominal surgery and complications, erythrocyte function and pathophysiology, and IL-33, ST2, and ILC pathways.

The scientist has collaborated frequently with researchers including Roberto Sitia, Marco Gattorno, Patrizia Castellani, Marco E. Bianchi, and Arinna Bertoni.

Anna Rubartelli has published work in various scientific venues. Frequent publication outlets include:

  • British Journal of Surgery
  • Methods in Molecular Biology
  • Science Translational Medicine
  • Journal of Allergy and Clinical Immunology
  • Journal of Biological Chemistry

Their recent papers illustrate the scope of their research contributions. These include:

  • "Rebalancing expression of HMGB1 redox isoforms to counteract muscular dystrophy," 2021, Science Translational Medicine
  • "Spontaneous NLRP3 inflammasome-driven IL-1-β secretion is induced in severe COVID-19 patients and responds to anakinra treatment," 2022, Journal of Allergy and Clinical Immunology
  • "Evolution, role in inflammation, and redox control of leaderless secretory proteins," 2020, Journal of Biological Chemistry
  • "CXCR4 engagement triggers CD47 internalization and antitumor immunization in a mouse model of mesothelioma," 2021, EMBO Molecular Medicine
  • "Pyrin Inflammasome Activation Defines Colchicine-Responsive SURF Patients from FMF and Other Recurrent Fevers," 2024, Journal of Clinical Immunology

Best Publications

  • Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion

    Tiziana Bonaldi;Fabio Talamo;Paola Scaffidi;Denise Ferrera

  • The nuclear protein HMGB1 is secreted by monocytes via a non-classical, vesicle-mediated secretory pathway

    Stefania Gardella;Cristina Andrei;Denise Ferrera;Lavinia V Lotti

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies

    Andrea Cossarizza;Hyun Dong Chang;Andreas Radbruch;Mübeccel Akdis

  • A novel secretory pathway for interleukin-1 beta, a protein lacking a signal sequence.

    A. Rubartelli;F. Cozzolino;M. Talio;R. Sitia

  • Differential requirement for the activation of the inflammasome for processing and release of IL-1beta in monocytes and macrophages.

    Mihea G Netea;Mihea G Netea;Claudia Annelie Nold-Petry;Marcel F Nold;Leo A B Joosten

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

    Andrea Cossarizza;Hyun Dong Chang;Andreas Radbruch;Andreas Acs

  • Consensus guidelines for the detection of immunogenic cell death

    Oliver Kepp;Laura Senovilla;Ilio Vitale;Erika Vacchelli

  • The grateful dead: damage-associated molecular pattern molecules and reduction/oxidation regulate immunity.

    Michael T. Lotze;Herbert J. Zeh;Anna Rubartelli;Louis J. Sparvero

  • Inside, outside, upside down: damage-associated molecular-pattern molecules (DAMPs) and redox.

    Anna Rubartelli;Michael T. Lotze

  • The Secretory Route of the Leaderless Protein Interleukin 1β Involves Exocytosis of Endolysosome-related Vesicles

    Cristina Andrei;Cecilia Dazzi;Lavinia Lotti;Maria Rosaria Torrisi

  • Secretion of thioredoxin by normal and neoplastic cells through a leaderless secretory pathway.

    A Rubartelli;A Bajetto;G Allavena;E Wollman

  • Phospholipases C and A2 control lysosome-mediated IL-1β secretion: Implications for inflammatory processes

    Cristina Andrei;Paola Margiocco;Alessandro Poggi;Lavinia V. Lotti

  • ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1β and IL-18 secretion in an autocrine way

    Alessandra Piccini;Sonia Carta;Sara Tassi;Denise Lasiglié

  • Nerve Growth Factor Is an Autocrine Survival Factor for Memory B Lymphocytes

    Maria Torcia;Luisa Bracci-Laudiero;Maria Lucibello;Lucia Nencioni

  • Masquerader : High mobility group box-1 and cancer

    Jessica E. Ellerman;Charles K. Brown;Michael de Vera;Herbert J. Zeh

  • OLT1177, a β-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation.

    Carlo Marchetti;Benjamin Swartzwelter;Fabia Gamboni;Charles P. Neff

  • The pattern of response to anti-interleukin-1 treatment distinguishes two subsets of patients with systemic-onset juvenile idiopathic arthritis.

    Marco Gattorno;Alessandra Piccini;Denise Lasigliè;Sara Tassi

  • Antigen-presenting dendritic cells provide the reducing extracellular microenvironment required for T lymphocyte activation

    Giovanna Angelini;Stefania Gardella;Massimo Ardy;Maria Rosa Ciriolo

  • A novel pathway for secretory proteins

    Anne Muesch;Enno Hartmann;Klaus Rohde;Anna Rubartelli

  • IL-1 family nomenclature

    Charles Dinarello;William Arend;John Sims;Dirk Smith

Frequent Co-Authors

Roberto Sitia
Roberto Sitia Vita-Salute San Raffaele University
Marco Gattorno
Marco Gattorno Istituto Giannina Gaslini
Alberto Martini
Alberto Martini University of Genoa
Alessandro Poggi
Alessandro Poggi University of Modena and Reggio Emilia
Charles A. Dinarello
Charles A. Dinarello University of Colorado Anschutz Medical Campus
Isabella Ceccherini
Isabella Ceccherini University of Genoa
Marco Bianchi
Marco Bianchi Vita-Salute San Raffaele University
Michael T. Lotze
Michael T. Lotze University of Pittsburgh
Maria Rosaria Torrisi
Maria Rosaria Torrisi Sapienza University of Rome
Leo A. B. Joosten
Leo A. B. Joosten Radboud University

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