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Junji Yodoi

Junji Yodoi

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Microbiology
Japan
2026
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Biology and Biochemistry
Japan
2023

D-Index & Metrics

Microbiology

D-Index
116
Citations
49969
World Ranking
183
National Ranking
2

Research.com Recognitions

  • 2026 - Research.com Microbiology in Japan Leader Award
  • 2025 - Research.com Microbiology in Japan Leader Award
  • 2023 - Research.com Biology and Biochemistry in Japan Leader Award

Overview

Junji Yodoi is affiliated with Kyoto University in Japan and works primarily within the fields of Biochemistry, Genetics and Molecular Biology, Immunology and Microbiology, and Medicine. Their scholarly contributions span multiple subfields including Molecular Biology, Immunology, Surgery, Biochemistry, and Cancer Research.

Their research focuses on several key topics such as Macrophage Migration Inhibitory Factor, Redox biology and oxidative stress, Cardiovascular, Neuropeptides, and Oxidative Stress Research, Inflammasome and immune disorders, Heme Oxygenase-1 and Carbon Monoxide, Sulfur Compounds in Biology, and Cancer, Hypoxia, and Metabolism.

Junji Yodoi has published research in a variety of scientific journals, addressing topics related to immune response mechanisms and redox biology. Frequent publication venues include:

  • Frontiers in Immunology
  • Antioxidants and Redox Signaling
  • Sleep And Breathing
  • Journal of Biological Chemistry
  • Free Radical Research

Recent papers authored or coauthored by Junji Yodoi include the following:

  • "Thioredoxin-1: A Promising Target for the Treatment of Allergic Diseases," 2022, Frontiers in Immunology
  • "Redoxisome Update: TRX and TXNIP/TBP2-Dependent Regulation of NLRP-1/NLRP-3 Inflammasome," 2024, Antioxidants and Redox Signaling
  • "Prospect of thioredoxin as a possibly effective tool to combat OSAHS," 2022, Sleep And Breathing
  • "Retraction: Nitric Oxide Induces Hypoxia-inducible Factor 1 Activation That Is Dependent on MAPK and Phosphatidylinositol 3-Kinase Signaling," 2025, Journal of Biological Chemistry
  • "Thioredoxin improves contact dermatitis through an anti-inflammatory mechanism different from glucocorticoids," 2025, Free Radical Research

Throughout their career, Junji Yodoi has collaborated frequently with several researchers. Key coauthors include:

  • Hai Tian
  • Jiedong Zhou
  • Cuixue Wang
  • Atsushi Fukunaga
  • Akira Yamauchi

The scientific work conducted by Junji Yodoi primarily investigates the molecular mechanisms underlying oxidative stress and inflammatory processes, with a focus on redox-regulatory proteins such as thioredoxin. This involves exploring their role in immune disorders, cardiovascular conditions, and cancer metabolism, contributing to a multidisciplinary understanding of biomedical challenges.

Best Publications

  • Adult T-cell leukemia: clinical and hematologic features of 16 cases

    Takashi Uchiyama;Junji Yodoi;Kimitaka Sagawa;Kiyoshi Takatsuki

  • REDOX REGULATION OF CELLULAR ACTIVATION

    Hajime Nakamura;Kazuhiro Nakamura;Junji Yodoi

  • Persistent oxidative stress in cancer

    Shinya Toyokuni;Keisei Okamoto;Junji Yodoi;Hiroshi Hiai

  • Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

    Seth L Masters;Aisling Dunne;Shoba L Subramanian;Rebecca L Hull

  • Thioredoxin regulates the DNA binding activity of NF-kappa B by reduction of a disulphide bond involving cysteine 62.

    James R. Matthews;Naomi Wakasugi;Jean-Louis virelizier;Junji Yodoi

  • AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1

    Kiichi Hirota;Minoru Matsui;Satoshi Iwata;Akira Nishiyama

  • Identification of Thioredoxin-binding Protein-2/Vitamin D3 Up-regulated Protein 1 as a Negative Regulator of Thioredoxin Function and Expression

    Akira Nishiyama;Minoru Matsui;Satoshi Iwata;Kiichi Hirota

  • Molecular cloning of cDNA encoding human interleukin-2 receptor

    Toshio Nikaido;Akira Shimizu;Norio Ishida;Hisataka Sabe

  • Distinct roles of thioredoxin in the cytoplasm and in the nucleus. A two-step mechanism of redox regulation of transcription factor NF-kappaB.

    Kiichi Hirota;Miyahiko Murata;Yoshifumi Sachi;Hajime Nakamura

  • Molecular mechanisms of transcription activation by HLF and HIF1alpha in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300.

    Masatsugu Ema;Kiichi Hirota;Junsei Mimura;Hisaku Abe

  • Redox Control of Cell Death

    Shugo Ueda;Hiroshi Masutani;Hajime Nakamura;Toru Tanaka

  • Early embryonic lethality caused by targeted disruption of the mouse thioredoxin gene

    Minoru Matsui;Minoru Matsui;Masanobu Oshima;Hiroko Oshima;Kazuaki Takaku

  • Thioredoxin-dependent Redox Regulation of p53-mediated p21 Activation

    Masaya Ueno;Hiroshi Masutani;Roberto Jun Arai;Akira Yamauchi

  • Amyloid β induces neuronal cell death through ROS-mediated ASK1 activation

    H. Kadowaki;H. Kadowaki;H. Nishitoh;H. Nishitoh;Fumihiko Urano;C. Sadamitsu

  • TCGF (IL 2)-receptor inducing factor(s). I. Regulation of IL 2 receptor on a natural killer-like cell line (YT cells).

    J Yodoi;K Teshigawara;T Nikaido;K Fukui

  • Overexpression of thioredoxin in transgenic mice attenuates focal ischemic brain damage.

    Yasushi Takagi;Akira Mitsui;Akira Nishiyama;Kazuhiko Nozaki

  • Thioredoxin, a Redox Enzyme Released in Infection and Inflammation, Is a Unique Chemoattractant for Neutrophils, Monocytes, and T Cells

    Riccardo Bertini;O.M. Zack Howard;Hui-Fang Dong;Joost J. Oppenheim

  • Glutaredoxin Exerts an Antiapoptotic Effect by Regulating the Redox State of Akt

    Hiroaki Murata;Yoshito Ihara;Hajime Nakamura;Junji Yodoi

  • Thioredoxin-2 (TRX-2) is an essential gene regulating mitochondria-dependent apoptosis.

    Toru Tanaka;Fumihito Hosoi;Yuko Yamaguchi-Iwai;Hajime Nakamura

  • A comparative study on the hydroperoxide and thiol specificity of the glutathione peroxidase family and selenoprotein P.

    Gen Takebe;Junko Yarimizu;Yoshiro Saito;Takaaki Hayashi

  • Hemin-induced activation of the thioredoxin gene by Nrf2. A differential regulation of the antioxidant responsive element by a switch of its binding factors.

    Yong Chul Kim;Hiroshi Masutani;Yoshimi Yamaguchi;Ken Itoh

Frequent Co-Authors

Hajime Nakamura
Hajime Nakamura Kyoto University
Hiroshi Masutani
Hiroshi Masutani Tenri Health Care University
Kiichi Hirota
Kiichi Hirota Kansai Medical University
Yutaka Tagaya
Yutaka Tagaya University of Maryland, Baltimore
Akira Nishiyama
Akira Nishiyama Kagawa University
Michiyuki Maeda
Michiyuki Maeda Kyoto University
Takashi Uchiyama
Takashi Uchiyama Kyoto University
Kiyoshi Takatsuki
Kiyoshi Takatsuki Kumamoto University
Tasuku Honjo
Tasuku Honjo Kyoto University
Hisao Ogawa
Hisao Ogawa Kumamoto University

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