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Immunology

D-Index
43
Citations
11142
World Ranking
4816
National Ranking
2162

Overview

Yutaka Tagaya is affiliated with the University of Maryland, Baltimore in the United States. Their research spans key areas within Immunology and Microbiology and Medicine, focusing on subfields including Immunology, Virology, Infectious Diseases, Molecular Biology, and Dermatology.

The scientific work of Tagaya covers a range of topics, notably:

  • HIV Research and Treatment
  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • HIV/AIDS drug development and treatment
  • Vaccines and immunoinformatics approaches
  • Lymphoma Diagnosis and Treatment
  • Immunotherapy and Immune Responses

They have contributed to publications in several journals, with repeated publications in prominent venues such as:

  • Blood
  • Journal of Translational Medicine
  • EBioMedicine
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Scientific Reports

Some recent papers authored or co-authored by Tagaya include:

  • "Coagulation potential and the integrated omics of extracellular vesicles from COVID-19 positive patient plasma," 2022, Scientific Reports
  • "Effective treatment with the selective cytokine inhibitor BNZ-1 reveals the cytokine dependency of T-LGL leukemia," 2023, Blood
  • "Identifying CCR5 coreceptor populations permissive for HIV-1 entry and productive infection: implications for in vivo studies," 2022, Journal of Translational Medicine
  • "Inflammatory monocyte-derived dendritic cells mediate autoimmunity in murine model of systemic lupus erythematosus," 2020, Journal of Translational Autoimmunity
  • "Tracking coreceptor switch of the transmitted/founder HIV-1 identifies co-evolution of HIV-1 antigenicity, coreceptor usage and CD4 subset targeting: the RV217 acute infection cohort study," 2023, EBioMedicine

Frequent collaborators include:

  • Saini Setua
  • Manukumar Honnayakanahalli Marichannegowda
  • Michelle Zemil
  • Lindsay Wieczorek
  • Eric Sanders-Buell

Best Publications

  • IL-15Rα Recycles and Presents IL-15 In trans to Neighboring Cells

    Sigrid Dubois;Jennifer Mariner;Thomas A Waldmann;Yutaka Tagaya

  • The multifaceted regulation of interleukin-15 expression and the role of this cytokine in NK cell differentiation and host response to intracellular pathogens.

    Waldmann Ta;Tagaya Y

  • IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8+ T Cells

    Christopher A. Klebanoff;Steven E. Finkelstein;Deborah R. Surman;Michael K. Lichtman;Michael K. Lichtman

  • ATL‐derived factor (ADF), an IL‐2 receptor/Tac inducer homologous to thioredoxin; possible involvement of dithiol‐reduction in the IL‐2 receptor induction.

    Y. Tagaya;Y. Maeda;A. Mitsui;N. Kondo

  • Contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: implications for immunotherapy.

    Thomas A. Waldmann;Sigrid Dubois;Yutaka Tagaya

  • IL-2-induced activation-induced cell death is inhibited in IL-15 transgenic mice.

    Joanna Marks-Konczalik;Sigrid Dubois;Jacqueline M. Losi;Helen Sabzevari

  • IL-15: a pleiotropic cytokine with diverse receptor/signaling pathways whose expression is controlled at multiple levels.

    Yutaka Tagaya;Richard N Bamford;Andrew P DeFilippis;Thomas A Waldmann

  • Requirement for IRF-1 in the microenvironment supporting development of natural killer cells

    Kouetsu Ogasawara;Shigeaki Hida;Nazli Azimi;Yutaka Tagaya

  • Role of trans-cellular IL-15 presentation in the activation of NK cell-mediated killing, which leads to enhanced tumor immunosurveillance.

    Hisataka Kobayashi;Sigrid Dubois;Noriko Sato;Helen Sabzevari

  • Adjuvant IL-7 or IL-15 overcomes immunodominance and improves survival of the CD8+ memory cell pool

    Fraia Melchionda;Terry J. Fry;Matthew J. Milliron;Melissa A. McKirdy

  • Interleukin-2, interleukin-15, and their receptors.

    Thomas Waldmann;Yutaka Tagaya;Richard Bamford

  • Generation of secretable and nonsecretable interleukin 15 isoforms through alternate usage of signal peptides

    Yutaka Tagaya;Gloria Kurys;Tiffany A. Thies;Jacqueline M. Losi

  • Human T cell lymphotropic virus type I Tax protein trans-activates interleukin 15 gene transcription through an NF-κB site

    Nazli Azimi;Keith Brown;Richard N. Bamford;Yutaka Tagaya

  • Human lymphocyte Fc receptor for IgE: sequence homology of its cloned cDNA with animal lectins.

    Koichi Ikuta;Masaaki Takami;Choong Won Kim;Tasuku Honjo

  • Adjuvant IL-7 or IL-15 overcomes immunodominance and improves survival of the CD8+ memory cell pool

    Unknown

  • Identification of a novel receptor/signal transduction pathway for IL‐15/T in mast cells

    Yutaka Tagaya;Jack D Burton;Yoshihisa Miyamoto;Thomas A Waldmann

  • Lymphatic drainage imaging of breast cancer in mice by micro-magnetic resonance lymphangiography using a nano-size paramagnetic contrast agent.

    Hisataka Kobayashi;Satomi Kawamoto;Yoshio Sakai;Peter L. Choyke

  • Expression and growth-promoting effect of adult T-cell leukemia-derived factor. A human thioredoxin homologue in hepatocellular carcinoma.

    Hajime Nakamura;Hiroshi Masutani;Yutaka Tagaya;Akira Yamauchi

  • Interleukin-2-Dependent Mechanisms of Tolerance and Immunity In Vivo

    Paul A Antony;Chrystal M Paulos;Mojgan Ahmadzadeh;Akgül Akpinarli

  • The IL-15/IL-15Rα on cell surfaces enables sustained IL-15 activity and contributes to the long survival of CD8 memory T cells

    Noriko Sato;Hiral J. Patel;Thomas A. Waldmann;Yutaka Tagaya

  • HIV infection-associated immune activation occurs by two distinct pathways that differentially affect CD4 and CD8 T cells

    Marta Catalfamo;Michele Di Mascio;Zonghui Hu;Sharat Srinivasula

  • The Long Signal Peptide Isoform and Its Alternative Processing Direct the Intracellular Trafficking of Interleukin-15

    Gloria Kurys;Yutaka Tagaya;Richard Bamford;John A. Hanover

  • Acquisition of CD80 (B7-1) by T Cells

    Helen Sabzevari;Judy Kantor;Adnan Jaigirdar;Yutaka Tagaya

Frequent Co-Authors

Junji Yodoi
Junji Yodoi Kyoto University
Thomas A. Waldmann
Thomas A. Waldmann National Institutes of Health
Michiyuki Maeda
Michiyuki Maeda Kyoto University
Tasuku Honjo
Tasuku Honjo Kyoto University
Steven Jacobson
Steven Jacobson National Institutes of Health
Juan M. Zapata
Juan M. Zapata Spanish National Research Council
Hiroshi Masutani
Hiroshi Masutani Tenri Health Care University
Masao Matsuoka
Masao Matsuoka Kumamoto University
Marvin S. Reitz
Marvin S. Reitz University of Maryland, Baltimore
Keiko Ozato
Keiko Ozato Eunice Kennedy Shriver National Institute of Child Health and Human Development

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