D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 43 Citations 8,938 82 World Ranking 14198 National Ranking 299

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Apoptosis
  • Cancer

His primary areas of study are Cancer research, Apoptosis, Programmed cell death, Cell biology and Signal transduction. The Cancer research study combines topics in areas such as XIAP, Chronic lymphocytic leukemia, Leukemia, Immunology and Tumor progression. His Apoptosis study combines topics in areas such as Cancer and Mitochondrion.

His work in Programmed cell death tackles topics such as TRAF4 which are related to areas like Protein structure, TRAF1, TRAF2, SPOP and Peptide sequence. His research investigates the connection with Cell biology and areas like CD40 which intersect with concerns in Tumor necrosis factor alpha, Cell–cell interaction, Follicular dendritic cells, Cell adhesion molecule and Dendritic cell. His Signal transduction research is multidisciplinary, relying on both Tumor Necrosis Factor Receptor-Associated Factors and Trk receptor, Neurotrophin.

His most cited work include:

  • Expression of apoptosis-regulating proteins in chronic lymphocytic leukemia: Correlations with in vitro and in vivo chemoresponses (621 citations)
  • Immunohistochemical Analysis of in Vivo Patterns of Expression of CPP32 (Caspase-3), a Cell Death Protease (414 citations)
  • The Bioenergetic Signature of Cancer: A Marker of Tumor Progression (374 citations)

What are the main themes of his work throughout his whole career to date?

Juan M. Zapata spends much of his time researching Cancer research, Molecular biology, Cell biology, Apoptosis and Chronic lymphocytic leukemia. His Cancer research research is multidisciplinary, incorporating perspectives in XIAP, Immunology, Cancer immunotherapy, Signal transduction and Programmed cell death. His Molecular biology study integrates concerns from other disciplines, such as Heat shock protein, Cell culture, B cell and Receptor, TRAF3.

The Cell biology study combines topics in areas such as Cell cycle, Ubiquitin and Cell–cell interaction. His study looks at the relationship between Apoptosis and topics such as Immunohistochemistry, which overlap with Bcl-2 family. His studies in Chronic lymphocytic leukemia integrate themes in fields like B-cell lymphoma, B-cell activating factor and In vivo.

He most often published in these fields:

  • Cancer research (38.83%)
  • Molecular biology (34.95%)
  • Cell biology (28.16%)

What were the highlights of his more recent work (between 2017-2021)?

  • Cancer research (38.83%)
  • B cell (16.50%)
  • T cell (8.74%)

In recent papers he was focusing on the following fields of study:

Cancer research, B cell, T cell, B-cell lymphoma and Molecular biology are his primary areas of study. His Cancer research study combines topics from a wide range of disciplines, such as Cell culture, Systemic administration, CD8, Cancer immunotherapy and Receptor. His work deals with themes such as Cancer and Interleukin 15, which intersect with Receptor.

His T cell research incorporates elements of T-cell leukemia and Kinase, TRAF3. His B-cell lymphoma research includes elements of Chronic lymphocytic leukemia, [email protected], Immunoglobulin D, breakpoint cluster region and B-cell activating factor. Molecular biology and Plasma cell neoplasm are two areas of study in which Juan M. Zapata engages in interdisciplinary work.

Between 2017 and 2021, his most popular works were:

  • A tumor-targeted trimeric 4-1BB-agonistic antibody induces potent anti-tumor immunity without systemic toxicity. (49 citations)
  • CD137 (4-1BB) Signalosome: Complexity Is a Matter of TRAFs. (27 citations)
  • Dysregulated TRAF3 and BCL2 Expression Promotes Multiple Classes of Mature Non-hodgkin B Cell Lymphoma in Mice (7 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Apoptosis
  • Cancer

Juan M. Zapata focuses on Immunoglobulin D, Molecular biology, B-cell lymphoma, B cell homeostasis and B cell. His studies deal with areas such as Gene rearrangement, Somatic hypermutation and Diffuse large B-cell lymphoma as well as Immunoglobulin D.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Expression of apoptosis-regulating proteins in chronic lymphocytic leukemia: Correlations with in vitro and in vivo chemoresponses

Shinichi Kitada;Janet Andersen;Sophie Akar;Juan M. Zapata.
Blood (1998)

843 Citations

Immunohistochemical Analysis of in Vivo Patterns of Expression of CPP32 (Caspase-3), a Cell Death Protease

Maryla Krajewska;Hong Gang Wang;Stanislaw Krajewski;Juan M. Zapata.
Cancer Research (1997)

606 Citations

The Bioenergetic Signature of Cancer: A Marker of Tumor Progression

José M Cuezva;Maryla Krajewska;Miguel López de Heredia;Stanislaw Krajewski.
Cancer Research (2002)

513 Citations

Protein kinase inhibitors flavopiridol and 7-hydroxy-staurosporine down-regulate antiapoptosis proteins in B-cell chronic lymphocytic leukemia.

Shinichi Kitada;Juan M. Zapata;Michael Andreeff;John C. Reed.
Blood (2000)

328 Citations

Protection of CLL B cells by a follicular dendritic cell line is dependent on induction of Mcl-1.

Irene M. Pedersen;Shinichi Kitada;Lorenzo M. Leoni;Juan M. Zapata.
Blood (2002)

298 Citations

Expression and location of Hsp70/Hsc-binding anti-apoptotic protein BAG-1 and its variants in normal tissues and tumor cell lines.

Shinichi Takayama;Stanislaw Krajewski;Maryla Krajewska;Shinichi Kitada.
Cancer Research (1998)

267 Citations

Prognostic significance of apoptosis regulators in breast cancer.

S Krajewski;M Krajewska;B C Turner;C Pratt.
Endocrine-related Cancer (1999)

251 Citations

A Diverse Family of Proteins Containing Tumor Necrosis Factor Receptor-associated Factor Domains

Juan M. Zapata;Krzysztof Pawlowski;Elvira Haas;Carl F. Ware.
Journal of Biological Chemistry (2001)

248 Citations

CD40-induced growth inhibition in epithelial cells is mimicked by Epstein-Barr Virus-encoded LMP1: involvement of TRAF3 as a common mediator.

A G Eliopoulos;C W Dawson;G Mosialos;J E Floettmann.
Oncogene (1996)

240 Citations

p53-inducible human homologue of Drosophila seven in absentia (Siah) inhibits cell growth : suppression by BAG-1

Shu‐ichi Matsuzawa;Shinichi Takayama;Barbara A. Froesch;Juan M. Zapata.
The EMBO Journal (1998)

232 Citations

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