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Carlos López-Otín

Carlos López-Otín

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Molecular Biology
Spain
2026
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Genetics and Molecular Biology
Spain
2024

D-Index & Metrics

Molecular Biology

D-Index
155
Citations
145843
World Ranking
73
National Ranking
1

Research.com Recognitions

  • 2026 - Research.com Molecular Biology in Spain Leader Award
  • 2025 - Research.com Molecular Biology in Spain Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in Spain Leader Award
  • 2023 - Research.com Molecular Biology in Spain Leader Award
  • 2022 - Research.com Genetics and Molecular Biology in Spain Leader Award
  • 1998 - Member of Academia Europaea
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Carlos López-Otín is affiliated with the University of Oviedo in Spain. Their research focuses on the intersection of biochemistry, genetics, and molecular biology, with significant contributions in medicine. Their main subfields of study include molecular biology, physiology, cancer research, epidemiology, and oncology.

The scientist has an extensive record of publications addressing various key topics related to aging, disease mechanisms, and molecular regulation. Notable themes in their research include autophagy in disease and therapy, mitochondrial function and pathology, genetics, aging and longevity in model organisms, adipose tissue and metabolism, microRNA in disease regulation, RNA research and splicing, and telomeres, telomerase, and senescence.

Frequent co-authors collaborating with Carlos López-Otín have been:

  • Guido Kroemer
  • David Roiz-Valle
  • José M.P. Freije
  • Xurde M. Caravia
  • Gabriel Bretones

The scientist's work appears regularly in several prominent publication venues. The most frequent ones include bioRxiv (Cold Spring Harbor Laboratory), Aging Cell, Cell, The EMBO Journal, and Nature.

Recent papers by Carlos López-Otín cover diverse aspects of aging biology and health:

  • "Hallmarks of aging: An expanding universe" (2023), published in Cell
  • "Hallmarks of Health" (2020), published in Cell
  • "Meta-hallmarks of aging and cancer" (2023), published in Cell Metabolism

In addition to these, other highly cited research in related fields, though not authored by López-Otín, appear alongside their work, providing context for their research landscape.

Carlos López-Otín has been recognized with membership in prestigious organizations, including the Academia Europaea since 1998 and the European Molecular Biology Organization (EMBO).

Best Publications

  • The Hallmarks of Aging

    Carlos López-Otín;Maria A. Blasco;Linda Partridge;Manuel Serrano

  • Signatures of mutational processes in human cancer

    Ludmil B. Alexandrov;Serena Nik-Zainal;Serena Nik-Zainal;David C. Wedge;Samuel A. J. R. Aparicio

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

    Lorenzo Galluzzi;Ilio Vitale;Stuart A. Aaronson;John M. Abrams

  • Pan-cancer analysis of whole genomes

    Peter J. Campbell;Gad Getz;Jan O. Korbel;Joshua M. Stuart

  • Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

    Daniel J. Klionsky;Hagai Abeliovich;Patrizia Agostinis;Devendra K. Agrawal

  • Genome sequence of the Brown Norway rat yields insights into mammalian evolution

    Richard A. Gibbs;George M. Weinstock;Michael L. Metzker;Donna M. Muzny

  • Initial sequence of the chimpanzee genome and comparison with the human genome

    Tarjei S. Mikkelsen;LaDeana W. Hillier

  • International network of cancer genome projects

    Thomas J. Hudson;Thomas J. Hudson;Warwick Anderson;Axel Aretz;Anna D. Barker

  • Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia

    Xose S. Puente;Magda Pinyol;Víctor Quesada;Laura Conde

  • Strategies for MMP inhibition in cancer: innovations for the post-trial era

    Christopher Mark Overall;Carlos López-Otín

  • Molecular definitions of autophagy and related processes

    Lorenzo Galluzzi;Lorenzo Galluzzi;Eric H. Baehrecke;Andrea Ballabio;Patricia Boya

  • Autophagy in major human diseases

    Daniel J. Klionsky;Giulia Petroni;Ravi K. Amaravadi;Eric H. Baehrecke

  • Proteases: Multifunctional Enzymes in Life and Disease

    Carlos López-Otín;Judith S. Bond

  • Human and mouse proteases: a comparative genomic approach

    Xose S. Puente;Luis M. Sánchez;Christopher M. Overall;Carlos López-Otín

  • Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia.

    Víctor Quesada;Laura Conde;Neus Villamor;Gonzalo R Ordóñez

  • Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

    L. Galluzzi;J. M. Bravo-San Pedro;I. Vitale;S. A. Aaronson

  • Biochemical Characterization of Human Collagenase-3

    Vera Knäuper;Carlos López-Otin;Bryan Smith;Graham Knight

  • Molecular cloning and expression of collagenase-3, a novel human matrix metalloproteinase produced by breast carcinomas.

    José M.P. Freije;Irene Díez-Itza;Milagros Balbín;Luis M. Sánchez

Frequent Co-Authors

Xose S. Puente
Xose S. Puente University of Oviedo
José M. P. Freije
José M. P. Freije University of Oviedo
Víctor Quesada
Víctor Quesada University of Oviedo
Elias Campo
Elias Campo University of Barcelona
Alberto M. Pendás
Alberto M. Pendás University of Salamanca
Guillermo Mariño
Guillermo Mariño University of Oviedo
Armando López-Guillermo
Armando López-Guillermo University of Barcelona
Guido Kroemer
Guido Kroemer Université Paris Cité
Neus Villamor
Neus Villamor University of Barcelona
Sílvia Beà
Sílvia Beà University of Barcelona

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