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Biology and Biochemistry

D-Index
66
Citations
21460
World Ranking
8492
National Ranking
148

Overview

Sílvia Beà is affiliated with the University of Barcelona in Spain and has contributed extensively to research in Medicine, with notable focus in Biochemistry, Genetics, and Molecular Biology. Their research covers a range of subfields including Pathology and Forensic Medicine, Genetics, Molecular Biology, Immunology, and Oncology.

The scientist's work primarily addresses topics related to Lymphoma Diagnosis and Treatment, Chronic Lymphocytic Leukemia Research, Cancer Genomics and Diagnostics, Viral-associated Cancers and Disorders, Immunodeficiency and Autoimmune Disorders, Genomic Variations and Chromosomal Abnormalities, and Acute Myeloid Leukemia Research.

Beà has coauthored numerous publications with several frequent collaborators including Elías Campo, Ferran Nadeu, Eva Giné, Armando López-Guillermo, and Cristina López.

Their research has been published in multiple scientific venues, with the most frequent being Hematological Oncology, Blood, Blood Advances, Leukemia, and HemaSphere.

Among recent papers, notable titles include:

  • Genomic and epigenomic insights into the origin, pathogenesis, and clinical behavior of mantle cell lymphoma subtypes, 2020, Blood
  • Dynamics of genome architecture and chromatin function during human B cell differentiation and neoplastic transformation, 2021, Nature Communications
  • Detection of early seeding of Richter transformation in chronic lymphocytic leukemia, 2022, Nature Medicine
  • The proliferative history shapes the DNA methylome of B-cell tumors and predicts clinical outcome, 2020, Nature Cancer
  • Molecular Pathogenesis of Mantle Cell Lymphoma, 2020, Hematology/Oncology Clinics of North America

Best Publications

  • International network of cancer genome projects

    Thomas J. Hudson;Thomas J. Hudson;Warwick Anderson;Axel Aretz;Anna D. Barker

  • Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia

    Xose S. Puente;Magda Pinyol;Víctor Quesada;Laura Conde

  • Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia.

    Víctor Quesada;Laura Conde;Neus Villamor;Gonzalo R Ordóñez

  • Non-coding recurrent mutations in chronic lymphocytic leukaemia

    Xose S. Puente;Silvia Beà;Rafael Valdés-Mas;Neus Villamor

  • BMI-1 gene amplification and overexpression in hematological malignancies occur mainly in mantle cell lymphomas.

    Sílvia Beà;Frederic Tort;Magda Pinyol;Xavier Puig

  • Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia

    Marta Kulis;Simon Heath;Marina Bibikova;Ana C Queirós

  • Landscape of somatic mutations and clonal evolution in mantle cell lymphoma

    Sílvia Beà;Rafael Valdés-Mas;Alba Navarro;Itziar Salaverria

  • Diffuse large B-cell lymphoma subgroups have distinct genetic profiles that influence tumor biology and improve gene-expression-based survival prediction.

    Silvia Bea;Andreas Zettl;George Wright;Itziar Salaverria

  • Genomic and Gene Expression Profiling Defines Indolent Forms of Mantle Cell Lymphoma

    Verònica Fernàndez;Olga Salamero;Blanca Espinet;Francesc Solé

  • Diffuse Large B-Cell Lymphoma: Clinical and Biological Characterization and Outcome According to the Nodal or Extranodal Primary Origin

    Armando López-Guillermo;Luis Colomo;Mónica Jiménez;Francesc Bosch

  • Clinical impact of clonal and subclonal TP53, SF3B1, BIRC3, NOTCH1 and ATM mutations in chronic lymphocytic leukemia

    Ferran Nadeu;Julio Delgado;Cristina Royo;Tycho Baumann

  • p16INK4a Gene Inactivation by Deletions, Mutations, and Hypermethylation Is Associated With Transformed and Aggressive Variants of Non-Hodgkin's Lymphomas

    Magda Pinyol;Francesc Cobo;Silvia Bea;Pedro Jares

  • Increased number of chromosomal imbalances and high-level DNA amplifications in mantle cell lymphoma are associated with blastoid variants.

    Sı́lvia Beà;Maria Ribas;Jesús M. Hernández;Francesc Bosch

  • TRK-fused gene (TFG) is a new partner of ALK in anaplastic large cell lymphoma producing two structurally different TFG-ALK translocations.

    Luis Hernández;Magda Pinyol;Silvia Hernández;Silvia Beà

  • Molecular Subsets of Mantle Cell Lymphoma Defined by the IGHV Mutational Status and SOX11 Expression Have Distinct Biologic and Clinical Features

    Alba Navarro;Guillem Clot;Cristina Royo;Pedro Jares

  • Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia

    Sonja I. Berndt;Christine F. Skibola;Christine F. Skibola;Vijai Joseph;Nicola J. Camp

  • Specific Secondary Genetic Alterations in Mantle Cell Lymphoma Provide Prognostic Information Independent of the Gene Expression–Based Proliferation Signature

    Itziar Salaverria;Andreas Zettl;Sílvia Beà;Victor Moreno

  • NOTCH1 mutations identify a genetic subgroup of chronic lymphocytic leukemia patients with high risk of transformation and poor outcome.

    N Villamor;L Conde;A Martínez-Trillos;M Cazorla

  • CCND2 rearrangements are the most frequent genetic events in cyclin D1 mantle cell lymphoma

    Itziar Salaverria;Itziar Salaverria;Cristina Royo;Alejandra Carvajal-Cuenca;Guillem Clot

  • A B-cell epigenetic signature defines three biologic subgroups of chronic lymphocytic leukemia with clinical impact.

    Ana C Queirós;Neus Villamor;Guillem Clot;Alejandra Martínez-Trillos

Frequent Co-Authors

Elias Campo
Elias Campo University of Barcelona
Itziar Salaverria
Itziar Salaverria University of Barcelona
Armando López-Guillermo
Armando López-Guillermo University of Barcelona
Dolors Colomer
Dolors Colomer University of Barcelona
Neus Villamor
Neus Villamor University of Barcelona
Andreas Rosenwald
Andreas Rosenwald University of Würzburg
Xose S. Puente
Xose S. Puente University of Oviedo
German Ott
German Ott Robert Bosch (Germany)
Reiner Siebert
Reiner Siebert University of Ulm
Carlos López-Otín
Carlos López-Otín University of Oviedo

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