What is he best known for?
The fields of study he is best known for:
Garth Powis mainly investigates Biochemistry, Thioredoxin, Thioredoxin reductase, Glutathione peroxidase and Internal medicine.
He has researched Thioredoxin in several fields, including Proliferation index, Cell biology, Cysteine and Cytosol.
His Cysteine study combines topics in areas such as Stereochemistry and Active site.
Garth Powis has included themes like Ribonucleotide reductase, Glutaredoxin and Cell growth in his Thioredoxin reductase study.
As a member of one scientific family, Garth Powis mostly works in the field of Internal medicine, focusing on Oncology and, on occasion, Cancer therapy, Medical physics, Tumor biology, Cancer Imaging Program and Cancer treatment.
His study focuses on the intersection of Enzyme inhibitor and fields such as Myosin light-chain kinase with connections in the field of Kinase.
His most cited work include:
- Wortmannin, a Potent and Selective Inhibitor of Phosphatidylinositol-3-kinase (636 citations)
- Hypoxia: Importance in tumor biology, noninvasive measurement by imaging, and value of its measurement in the management of cancer therapy (505 citations)
- Properties and Biological Activities of Thioredoxins (391 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of study are Biochemistry, Cell growth, Thioredoxin, Cancer research and Internal medicine.
His study ties his expertise on Stereochemistry together with the subject of Biochemistry.
His research on Cell growth also deals with topics like
- Signal transduction and related Drug,
- Cell biology which connect with Cancer cell.
His work carried out in the field of Thioredoxin brings together such families of science as Molecular biology, Gene expression, Cysteine and Apoptosis.
While the research belongs to areas of Internal medicine, Garth Powis spends his time largely on the problem of Oncology, intersecting his research to questions surrounding Tumor biology.
His work in Thioredoxin reductase addresses issues such as Ribonucleotide reductase, which are connected to fields such as Cytosol.
He most often published in these fields:
- Biochemistry (37.50%)
- Cell growth (18.33%)
- Thioredoxin (18.33%)
What were the highlights of his more recent work (between 2012-2021)?
- Cancer research (15.00%)
- Cancer (9.17%)
- Cancer cell (10.83%)
In recent papers he was focusing on the following fields of study:
His primary scientific interests are in Cancer research, Cancer, Cancer cell, Internal medicine and Angiogenesis.
His Cancer research research includes themes of T cell, Chemokine, KRAS, Signal transduction and Gene silencing.
Garth Powis interconnects RHOA and Oncology in the investigation of issues within Internal medicine.
His research integrates issues of Pet tracer, Stereochemistry and Cell growth in his study of Kinase.
His research on Pet tracer often connects related areas such as Biochemistry.
Much of his study explores Biochemistry relationship to Covalent bond.
Between 2012 and 2021, his most popular works were:
- Phase II Pilot Study of Vemurafenib in Patients With Metastatic BRAF-Mutated Colorectal Cancer. (362 citations)
- ERK5 signalling rescues intestinal epithelial turnover and tumour cell proliferation upon ERK1/2 abrogation (40 citations)
- Definition of a Novel Feed-Forward Mechanism for Glycolysis-HIF1α Signaling in Hypoxic Tumors Highlights Aldolase A as a Therapeutic Target. (33 citations)
In his most recent research, the most cited papers focused on:
Garth Powis mostly deals with Cancer cell, Colorectal cancer, Internal medicine, Cell biology and Cancer.
His Cancer cell research is multidisciplinary, relying on both Tumor microenvironment, Cathepsin, Cathepsin B and Proteases.
His studies deal with areas such as Cellular differentiation, Oncology, Tumor biology, Genetic heterogeneity and Rash as well as Colorectal cancer.
Garth Powis has researched Oncology in several fields, including Chemotherapy regimen, Cohort study, Survival rate, Carcinoma and Melanoma.
His research in Internal medicine intersects with topics in Endocrinology and Immunology.
The study incorporates disciplines such as Carcinogenesis, Epithelium and Cell growth in addition to Cell biology.
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