2016 - Fellow, National Academy of Inventors
Garth Powis mainly investigates Biochemistry, Thioredoxin, Thioredoxin reductase, Glutathione peroxidase and Internal medicine. He has researched Thioredoxin in several fields, including Proliferation index, Cell biology, Cysteine and Cytosol. His Cysteine study combines topics in areas such as Stereochemistry and Active site.
Garth Powis has included themes like Ribonucleotide reductase, Glutaredoxin and Cell growth in his Thioredoxin reductase study. As a member of one scientific family, Garth Powis mostly works in the field of Internal medicine, focusing on Oncology and, on occasion, Cancer therapy, Medical physics, Tumor biology, Cancer Imaging Program and Cancer treatment. His study focuses on the intersection of Enzyme inhibitor and fields such as Myosin light-chain kinase with connections in the field of Kinase.
His primary areas of study are Biochemistry, Cell growth, Thioredoxin, Cancer research and Internal medicine. His study ties his expertise on Stereochemistry together with the subject of Biochemistry. His research on Cell growth also deals with topics like
His work carried out in the field of Thioredoxin brings together such families of science as Molecular biology, Gene expression, Cysteine and Apoptosis. While the research belongs to areas of Internal medicine, Garth Powis spends his time largely on the problem of Oncology, intersecting his research to questions surrounding Tumor biology. His work in Thioredoxin reductase addresses issues such as Ribonucleotide reductase, which are connected to fields such as Cytosol.
His primary scientific interests are in Cancer research, Cancer, Cancer cell, Internal medicine and Angiogenesis. His Cancer research research includes themes of T cell, Chemokine, KRAS, Signal transduction and Gene silencing. Garth Powis interconnects RHOA and Oncology in the investigation of issues within Internal medicine.
His research integrates issues of Pet tracer, Stereochemistry and Cell growth in his study of Kinase. His research on Pet tracer often connects related areas such as Biochemistry. Much of his study explores Biochemistry relationship to Covalent bond.
Garth Powis mostly deals with Cancer cell, Colorectal cancer, Internal medicine, Cell biology and Cancer. His Cancer cell research is multidisciplinary, relying on both Tumor microenvironment, Cathepsin, Cathepsin B and Proteases. His studies deal with areas such as Cellular differentiation, Oncology, Tumor biology, Genetic heterogeneity and Rash as well as Colorectal cancer.
Garth Powis has researched Oncology in several fields, including Chemotherapy regimen, Cohort study, Survival rate, Carcinoma and Melanoma. His research in Internal medicine intersects with topics in Endocrinology and Immunology. The study incorporates disciplines such as Carcinogenesis, Epithelium and Cell growth in addition to Cell biology.
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Wortmannin, a Potent and Selective Inhibitor of Phosphatidylinositol-3-kinase
G Powis;R Bonjouklian;R Bonjouklian;M M Berggren;M M Berggren;A Gallegos;A Gallegos.
Cancer Research (1994)
Hypoxia: Importance in tumor biology, noninvasive measurement by imaging, and value of its measurement in the management of cancer therapy
Jeffrey M. Arbeit;J. Martin Brown;K. S.Clifford Chao;J. Donald Chapman.
International Journal of Radiation Biology (2006)
The role of the redox protein thioredoxin in cell growth and cancer.
Garth Powis;Debbie Mustacich;Amy Coon.
Free Radical Biology and Medicine (2000)
The absence of mitochondrial thioredoxin 2 causes massive apoptosis, exencephaly, and early embryonic lethality in homozygous mice.
Larisa Nonn;Ryan R. Williams;Robert P. Erickson;Garth Powis.
Molecular and Cellular Biology (2003)
Effect of KRAS Oncogene Substitutions on Protein Behavior: Implications for Signaling and Clinical Outcome
Nathan T. Ihle;Lauren Averett Byers;Edward S. Kim;Pierre Saintigny.
Journal of the National Cancer Institute (2012)
Crystal structures of reduced, oxidized, and mutated human thioredoxins: evidence for a regulatory homodimer.
Andrzej Weichsel;John R Gasdaska;Garth Powis;William R Montfort.
Passing the baton: the HIF switch
Mei Yee Koh;Garth Powis.
Trends in Biochemical Sciences (2012)
Redox signalling and the control of cell growth and death
Garth Powis;Margaret Briehl;John Oblong.
Pharmacology & Therapeutics (1995)
HIF-1 regulation: not so easy come, easy go
Mei Yee Koh;Taly R. Spivak-Kroizman;Garth Powis.
Trends in Biochemical Sciences (2008)
Cytosolic NAD(P)H:(quinone-acceptor)oxidoreductase in human normal and tumor tissue : effects of cigarette smoking and alcohol
John J. Schlager;Garth Powis.
International Journal of Cancer (1990)
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