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David Siegel

D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
12801
World Ranking
13121
National Ranking
5596

David Siegel publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where David Siegel sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 413 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 848 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 949 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 840 scientists 207–216 publications: 733 scientists 217–226 publications: 708 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 417 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 196 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 59 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 137 publications — 20th percentile

20% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

David Siegel D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where David Siegel sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 316 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 899 scientists 52–53 D-Index: 1,025 scientists 54–55 D-Index: 1,149 scientists 56–57 D-Index: 1,235 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,162 scientists 62–63 D-Index: 1,130 scientists 64–65 D-Index: 1,031 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 714 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 71 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 58 D-Index — 34th percentile

34% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

David Siegel is affiliated with the University of California, Santa Barbara in the United States. Their research spans multiple fields, primarily within medicine and biochemistry, genetics, and molecular biology. Siegel's work is notably concentrated in areas such as molecular biology, toxicology, geriatrics and gerontology, oncology, and organic chemistry.

The scientist's publications cover several main topics, including:

  • Genomics, phytochemicals, and oxidative stress
  • Bioactive Compounds and Antitumor Agents
  • Sirtuins and Resveratrol in Medicine
  • Free Radicals and Antioxidants
  • Adipose Tissue and Metabolism
  • Histone Deacetylase Inhibitors Research
  • Heat shock proteins research

Siegel has contributed to various scientific journals, with frequent publications in the following venues:

  • Redox Biology
  • Journal of the American Academy of Dermatology
  • npj Aging and Mechanisms of Disease
  • Journal of Medicinal Chemistry
  • Bone

Among recent papers authored or co-authored by Siegel are:

  • "A redox-mediated conformational change in NQO1 controls binding to microtubules and α-tubulin acetylation", 2020, Redox Biology
  • "The diverse functionality of NQO1 and its roles in redox control", 2021, Redox Biology
  • "NQO1 protects obese mice through improvements in glucose and lipid metabolism", 2020, npj Aging and Mechanisms of Disease
  • "Geldanamycin, a Naturally Occurring Inhibitor of Hsp90 and a Lead Compound for Medicinal Chemistry", 2024, Journal of Medicinal Chemistry
  • "Off-on-off-on use of imatinib in three children with fibrodysplasia ossificans progressiva", 2021, Bone

Frequent collaborators in Siegel's work include:

  • David Ross
  • Rafael de Cabo
  • Kristofer S. Fritz
  • Andrea Di Francesco
  • Michel Bernier

Siegel's scholarly output reflects a multidisciplinary approach, with integration across redox biology, metabolic regulation, and medicinal chemistry. The prominence of co-authors such as David Ross and Andrea Di Francesco indicates ongoing collaborative efforts within these specialized areas.

Best Publications

  • NAD(P)H:Quinone Oxidoreductase 1: Role as a Superoxide Scavenger

    David Siegel;Daniel L. Gustafson;Donna L. Dehn;Jin Yi Han

  • First direct observation of a nearly ideal graphene band structure.

    M. Sprinkle;D. Siegel;Y. Hu;J. Hicks

  • NAD(P)H:Quinone Oxidoreductase Activity Is the Principal Determinant of β-Lapachone Cytotoxicity

    John J. Pink;Sarah M. Planchon;Colleen Tagliarino;Marie E. Varnes

  • Immunodetection of NAD(P)H:quinone oxidoreductase 1 (NQO1) in human tissues.

    David Siegel;David Ross

  • Characterization of a polymorphism in NAD(P)H: quinone oxidoreductase (DT-diaphorase).

    R.D. Traver;D. Siegel;H.D. Beall;Roger M. Phillips

  • Metal to insulator transition in epitaxial graphene induced by molecular doping.

    S. Y. Zhou;S. Y. Zhou;D. A. Siegel;D. A. Siegel;A. V. Fedorov;A. Lanzara;A. Lanzara

  • The Reduction of α-Tocopherolquinone by Human NAD(P)H:Quinone Oxidoreductase: The Role of α-Tocopherolhydroquinone as a Cellular Antioxidant

    David Siegel;Emiko M. Bolton;Jeanne A. Burr;Daniel C. Liebler

  • NAD(P)H:quinone oxidoreductase 1 (NQO1) in the sensitivity and resistance to antitumor quinones.

    David Siegel;Chao Yan;David Ross

  • NAD(P)H:quinone oxidoreductase 1 (NQO1, DT-diaphorase), functions and pharmacogenetics.

    David Ross;David Siegel

  • Functions of NQO1 in Cellular Protection and CoQ10 Metabolism and its Potential Role as a Redox Sensitive Molecular Switch.

    David Ross;David Siegel

  • Metabolism of mitomycin C by DT-diaphorase: role in mitomycin C-induced DNA damage and cytotoxicity in human colon carcinoma cells.

    David Siegel;Neil W. Gibson;Peter C. Preusch;David Ross

  • Rapid Polyubiquitination and Proteasomal Degradation of a Mutant Form of NAD(P)H:Quinone Oxidoreductase 1

    David Siegel;Adil Anwar;Shannon L. Winski;Jadwiga K. Kepa

  • The diverse functionality of NQO1 and its roles in redox control

    David Ross;David Siegel

  • DT-diaphorase in activation and detoxification of quinones. Bioreductive activation of mitomycin C.

    D Ross;D Siegel;H Beall;A S Prakash

  • Formation of 17-allylamino-demethoxygeldanamycin (17-AAG) hydroquinone by NAD(P)H:quinone oxidoreductase 1: role of 17-AAG hydroquinone in heat shock protein 90 inhibition.

    Wenchang Guo;Philip Reigan;David Siegel;Joseph Zirrolli

  • A potential mechanism underlying the increased susceptibility of individuals with a polymorphism in NAD(P)H:quinone oxidoreductase 1 (NQO1) to benzene toxicity.

    Julie L. Moran;David Siegel;David Ross

  • Immunohistochemical detection of NAD(P)H:quinone oxidoreductase in human lung and lung tumors

    D Siegel;W A Franklin;D Ross

  • Bioreductive activation of mitomycin C by DT-diaphorase.

    David Siegel;Howard Beall;Claudia Senekowitsch;Masaji Kasai

  • Interaction of human NAD(P)H:quinone oxidoreductase 1 (NQO1) with the tumor suppressor protein p53 in cells and cell-free systems.

    Adil Anwar;Donna Dehn;David Siegel;Jadwiga K. Kepa

  • Metabolism of diaziquone by NAD(P)H:(quinone acceptor) oxidoreductase (DT-diaphorase): role in diaziquone-induced DNA damage and cytotoxicity in human colon carcinoma cells.

    David Siegel;Neil W. Gibson;Peter C. Preusch;David Ross

Frequent Co-Authors

Alessandra Lanzara
Alessandra Lanzara University of California, Berkeley
Christopher J. Moody
Christopher J. Moody University of Nottingham
Shuyun Zhou
Shuyun Zhou Tsinghua University
Alexei V. Fedorov
Alexei V. Fedorov Lawrence Berkeley National Laboratory
Alex Zettl
Alex Zettl University of California, Berkeley
Kevin F. McCarty
Kevin F. McCarty Sandia National Laboratories
Michel Bernier
Michel Bernier National Institutes of Health
Andreas K. Schmid
Andreas K. Schmid Lawrence Berkeley National Laboratory
Rafael de Cabo
Rafael de Cabo National Institutes of Health
Steven G. Louie
Steven G. Louie University of California, Berkeley

External Links

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Related Online Degrees & Career Pathways

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Best Scientists Citing David Siegel

David A. Boothman

David A. Boothman

Indiana University

Publications: 60

Claire Berger

Claire Berger

Georgia Institute of Technology

Publications: 51

Christopher J. Moody

Christopher J. Moody

University of Nottingham

Publications: 33

Paul Workman

Paul Workman

Institute of Cancer Research

Publications: 31

Taiichi Otsuji

Taiichi Otsuji

Tohoku University

Publications: 27

Anil K. Jaiswal

Anil K. Jaiswal

University of Maryland, Baltimore

Publications: 26

Walt A. de Heer

Walt A. de Heer

Georgia Institute of Technology

Publications: 26

Victor Ryzhii

Victor Ryzhii

Tohoku University

Publications: 24

Ian J. Stratford

Ian J. Stratford

RMIT University

Publications: 22

Martyn T. Smith

Martyn T. Smith

University of California, Berkeley

Publications: 21

Kenji Watanabe

Kenji Watanabe

National Institute for Materials Science

Publications: 20

Patricia Muñoz

Patricia Muñoz

Hospital General Universitario Gregorio Marañón

Publications: 19

Albena T. Dinkova-Kostova

Albena T. Dinkova-Kostova

University of Dundee

Publications: 18

Takashi Taniguchi

Takashi Taniguchi

National Institute for Materials Science

Publications: 17

Alessandra Lanzara

Alessandra Lanzara

University of California, Berkeley

Publications: 17

Stephan Roche

Stephan Roche

Catalan Institution for Research and Advanced Studies

Publications: 16

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