David A. Boothman

Overview

Best Publications

• Multifunctional polymeric micelles as cancer-targeted, MRI-ultrasensitive drug delivery systems.

  Norased Nasongkla;Erik Bey;Jimin Ren;Hua Ai

  1513
  Citations

• Klotho Inhibits Transforming Growth Factor-β1 (TGF-β1) Signaling and Suppresses Renal Fibrosis and Cancer Metastasis in Mice

  Shigehiro Doi;Yonglong Zou;Osamu Togao;Johanne V. Pastor

  623
  Citations

• Review of poly (ADP-ribose) polymerase (PARP) mechanisms of action and rationale for targeting in cancer and other diseases.

  Julio C. Morales;Long Shan Li;Farjana J. Fattah;Ying Dong

  608
  Citations

• cRGD-functionalized polymer micelles for targeted doxorubicin delivery.

  Norased Nasongkla;Xintao Shuai;Hua Ai;Brent D. Weinberg

  560
  Citations

• Synthesis and functional analyses of nuclear clusterin, a cell death protein

  Konstantin S. Leskov;Dmitry Y. Klokov;Jing Li;Timothy J. Kinsella

  496
  Citations

• Ku70 suppresses the apoptotic translocation of Bax to mitochondria

  Motoshi Sawada;Weiyong Sun;Paulette Hayes;Konstantin Leskov

  460
  Citations

• NAD(P)H:Quinone Oxidoreductase Activity Is the Principal Determinant of β-Lapachone Cytotoxicity

  John J. Pink;Sarah M. Planchon;Colleen Tagliarino;Marie E. Varnes

  448
  Citations

• Challenge and promise: roles for clusterin in pathogenesis, progression and therapy of cancer

  B. Shannan;M. Seifert;K. Leskov;J. Willis

  398
  Citations

• An NQO1- and PARP-1-mediated cell death pathway induced in non-small-cell lung cancer cells by β-lapachone

  Erik A. Bey;Melissa S. Bentle;Kathryn E. Reinicke;Ying Dong

  385
  Citations

• Nuclear clusterin/XIP8, an x-ray-induced Ku70-binding protein that signals cell death

  Chin Rang Yang;Konstantin Leskov;Kelly Hosley-Eberlein;Tracy Criswell

  378
  Citations

• Role of the hMLH1 DNA Mismatch Repair Protein in Fluoropyrimidine-mediated Cell Death and Cell Cycle Responses

  Mark Meyers;Mark W. Wagner;Hwa-Shin Hwang;Timothy J. Kinsella

  336
  Citations

• Superparamagnetic iron oxide nanoparticles: Amplifying ros stress to improve anticancer drug efficacy

  Gang Huang;Huabing Chen;Ying Dong;Xiuquan Luo

  333
  Citations

• EGFRvIII and DNA Double-Strand Break Repair: A Molecular Mechanism for Radioresistance in Glioblastoma

  Bipasha Mukherjee;Brian McEllin;Cristel V. Camacho;Nozomi Tomimatsu

  327
  Citations

• Transcription factors activated in mammalian cells after clinically relevant doses of ionizing radiation.

  Tracy Criswell;Konstantin Leskov;Shigeki Miyamoto;Guangbin Luo

  306
  Citations

• β-Lapachone-mediated Apoptosis in Human Promyelocytic Leukemia (HL-60) and Human Prostate Cancer Cells: A p53-independent Response

  Sarah M. Planchon;Shelly Wuerzberger;Benjamin Frydman;Donald T. Witiak

  293
  Citations

• Role of DAB2IP in modulating epithelial-to-mesenchymal transition and prostate cancer metastasis

  Daxing Xie;Crystal Gore;Jun Liu;Rey Chen Pong

  272
  Citations

• Inhibition of Potentially Lethal DNA Damage Repair in Human Tumor Cells by β-Lapachone, an Activator of Topoisomerase I

  David A. Boothman;Douglas K. Trask;Arthur B. Pardee

  268
  Citations

• Identification and Characterization of X-Ray-induced Proteins in Human Cells

  David A. Boothman;Isabelle Bouvard;Edward N. Hughes

  249
  Citations

• Photoactivation switch from type II to type I reactions by electron-rich micelles for improved photodynamic therapy of cancer cells under hypoxia

  Huiying Ding;Haijun Yu;Ying Dong;Ruhai Tian

  237
  Citations

• Overcoming endosomal barrier by amphotericin B-loaded dual pH-responsive PDMA-b-PDPA micelleplexes for siRNA delivery.

  Haijun Yu;Yonglong Zou;Yiguang Wang;Xiaonan Huang

  229
  Citations