World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
54
Citations
11966
World Ranking
15524
National Ranking
6477

Overview

Noelle S. Williams is affiliated with The University of Texas Southwestern Medical Center in the United States. Their research spans multiple disciplines, primarily in Medicine and Biochemistry, Genetics and Molecular Biology. These fields are reflected through a significant number of publications and contributions to molecular biology, epidemiology, infectious diseases, cancer research, and oncology.

Williams's scientific work covers various specialized topics including:

  • Fungal Infections and Studies
  • Antifungal resistance and susceptibility
  • Biochemical and Molecular Research
  • Renal cell carcinoma treatment
  • Cancer, Lipids, and Metabolism
  • Peptidase Inhibition and Analysis
  • Cancer Genomics and Diagnostics

Several recent publications illustrate the scope of Williams's research interests and contributions. These papers include:

  • Reducing acetylated tau is neuroprotective in brain injury, 2021, published in Cell
  • A trimethoprim derivative impedes antibiotic resistance evolution, 2021, published in Nature Communications
  • A male-derived nonribosomal peptide pheromone controls female schistosome development, 2022, published in Cell
  • An oxindole efflux inhibitor potentiates azoles and impairs virulence in the fungal pathogen Candida auris, 2020, published in Nature Communications
  • Inhibition of the de novo pyrimidine biosynthesis pathway limits ribosomal RNA transcription causing nucleolar stress in glioblastoma cells, 2020, published in PLoS Genetics

Frequent co-authors in Williams's work indicate collaborative efforts with other researchers in the field. Key collaborators include Jessica A. Kilgore, Joseph M. Ready, Jef K. De Brabander, Jiwoong Kim, and Francisco Ortiz.

Williams's research output is published in a range of scientific venues, with repeated contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Journal of Medicinal Chemistry
  • Cell
  • Journal of Clinical Investigation

Their work incorporates methodologies and insights from molecular biology, epidemiology, and clinical studies, contributing to an understanding of infectious diseases, cancer biology, and biochemical mechanisms. This multidisciplinary approach is reflected in the diversity of publication outlets and collaborative networks.

Best Publications

  • Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer

    Baozhi Chen;Michael E. Dodge;Wei Tang;Jianming Lu

  • Targeting QseC Signaling and Virulence for Antibiotic Development

    David A. Rasko;Cristiano G. Moreira;De Run Li;Nicola C. Reading

  • Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15

    Ting Han;Maria Goralski;Nicholas Gaskill;Emanuela Capota

  • Discovery of a Proneurogenic, Neuroprotective Chemical

    Andrew A. Pieper;Shanhai Xie;Emanuela Capota;Sandi Jo Estill

  • Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration

    Yongyou Zhang;Amar Desai;Sung Yeun Yang;Sung Yeun Yang;Ki Beom Bae;Ki Beom Bae

  • Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma

    Yufeng Shi;S. Kyun Lim;Qiren Liang;Swathi V. Iyer

  • Identification and validation of genes involved in the pathogenesis of colorectal cancer using cDNA microarrays and RNA interference.

    Noelle Sevilir Williams;Richard B. Gaynor;Shane Scoggin;Udit Verma

  • Targeted inhibitors of P-glycoprotein increase chemotherapeutic-induced mortality of multidrug resistant tumor cells

    Amila K. Nanayakkara;Courtney A. Follit;Gang Chen;Noelle S. Williams

  • Identification of NF-κB-regulated genes induced by TNFα utilizing expression profiling and RNA interference

    Anwu Zhou;Shane Scoggin;Richard B Gaynor;Richard B Gaynor;Noelle Sevilir Williams

  • Development of Proneurogenic, Neuroprotective Small Molecules

    Karen S. MacMillan;Jacinth Naidoo;Jue Liang;Lisa Melito

  • Regulation of VEGF-induced endothelial cell migration by mitochondrial reactive oxygen species.

    Youxue Wang;Qun S. Zang;Zijuan Liu;Qian Wu

  • A Validated Tumorgraft Model Reveals Activity of Dovitinib Against Renal Cell Carcinoma

    Sharanya Sivanand;Samuel Peña-Llopis;Hong Zhao;Blanka Kucejova

  • Systematic Identification of Molecular Subtype-Selective Vulnerabilities in Non Small Cell Lung Cancer

    Hyun Seok Kim;Saurabh Mendiratta;Jiyeon Kim;Chad Victor Pecot

  • Generation of Lytic Natural Killer 1.1+, Ly-49− Cells from Multipotential Murine Bone Marrow Progenitors in a Stroma-free Culture: Definition of Cytokine Requirements and Developmental Intermediates

    Noelle Sevilir Williams;Thomas A. Moore;John D. Schatzle;Igor J. Puzanov

  • The P7C3 class of neuroprotective compounds exerts antidepressant efficacy in mice by increasing hippocampal neurogenesis

    Walker Ak;Rivera Pd;Wang Q;Chuang Jc

  • Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of amyotrophic lateral sclerosis

    Rachel Tesla;Hamilton Parker Wolf;Pin Xu;Jordan Drawbridge

  • Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of Parkinson disease

    Héctor De Jesús-Cortés;Pin Xu;Jordan Drawbridge;Sandi Jo Estill

  • Identification of a population of CD4+ CTL that utilizes a perforin- rather than a Fas ligand-dependent cytotoxic mechanism.

    Noelle Sevilir Williams;Victor H. Engelhard

  • Differentiation of NK1.1+, Ly49+ NK Cells from flt3+ Multipotent Marrow Progenitor Cells

    Noelle Sevilir Williams;Jennifer Klem;Igor J. Puzanov;P. V. Sivakumar

  • Structure/Activity Relationship Studies of Small-Molecule Inhibitors of Wnt Response

    Jianming Lu;Zhiqiang Ma;Jen Chieh Hsieh;Chih Wei Fan

Frequent Co-Authors

Andrew A. Pieper
Andrew A. Pieper University of Iowa
Jef K. De Brabander
Jef K. De Brabander The University of Texas Southwestern Medical Center
Lawrence G. Lum
Lawrence G. Lum University of Virginia
David A. Boothman
David A. Boothman Indiana University
Michael G. Roth
Michael G. Roth The University of Texas Southwestern Medical Center
Ralph J. DeBerardinis
Ralph J. DeBerardinis The University of Texas Southwestern Medical Center
Michael J. Bennett
Michael J. Bennett University Hospital Southampton NHS Foundation Trust
John D. Minna
John D. Minna The University of Texas Southwestern Medical Center
Michael A. White
Michael A. White Ideaya Biosciences (United States)
Steven L. McKnight
Steven L. McKnight The University of Texas Southwestern Medical Center

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Pursuing Biology and Biochemistry opens doors to various healthcare and science careers. Many students start by exploring ultrasound tech online programs, which combine biology foundations with hands-on healthcare roles.

For those interested in medical imaging, the cheapest radiology tech programs offer a cost-effective entry point to this fast-growing field. These programs can help graduates secure well-paying, in-demand jobs soon after completion.

Graduates with a focus on nutrition and public health may consider the best dietetics masters programs to further specialize and boost their career prospects.

Entry-level healthcare careers are also available through online training. Those seeking flexibility and support should explore financial aid for medical assistant programs.

These related online degrees and pathways allow students to advance their skills and find rewarding careers in the health sciences sector.

Best Scientists Citing Noelle S. Williams

Trending Scientists

Recently Published Articles