Jef K. De Brabander

Overview

Best Publications

• A Small Molecule Smac Mimic Potentiates TRAIL- and TNFα-Mediated Cell Death

  Lin Li;Ranny Mathew Thomas;Hidetaka Suzuki;Jef K. De Brabander

  1042
  Citations

• Cholesterol and 25-Hydroxycholesterol Inhibit Activation of SREBPs by Different Mechanisms, Both Involving SCAP and Insigs

  Christopher M. Adams;Julian Reitz;Jef K. De Brabander;Jamison D. Feramisco

  542
  Citations

• Identification of NPC1 as the target of U18666A, an inhibitor of lysosomal cholesterol export and Ebola infection

  Feiran Lu;Qiren Liang;Lina Abi-Mosleh;Akash Das

  328
  Citations

• Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma

  Yufeng Shi;S. Kyun Lim;Qiren Liang;Swathi V. Iyer

  320
  Citations

• Metal-catalyzed regioselective oxy-functionalization of internal alkynes: an entry into ketones, acetals, and spiroketals.

  Bo Liu;Jef K. De Brabander

  287
  Citations

• Development of Proneurogenic, Neuroprotective Small Molecules

  Karen S. MacMillan;Jacinth Naidoo;Jue Liang;Lisa Melito

  221
  Citations

• Total Synthesis and Absolute Configuration of the Novel Microtubule‐Stabilizing Agent Peloruside A

  Xibin Liao;Yusheng Wu;Jef K. De Brabander

  175
  Citations

• Lessons and revelations from biomimetic syntheses

  Mina Razzak;Jef K De Brabander

  153
  Citations

• Salicylihalamide A inhibits the V0 sector of the V-ATPase through a mechanism distinct from bafilomycin A1.

  Xiao Song Xie;David Padron;Xibin Liao;Jin Wang

  153
  Citations

• Synthesis and Complete Stereochemical Assignment of Psymberin/Irciniastatin A

  Xin Jiang;Jorge Garcia-Fortanet;Jef K. De Brabander

  139
  Citations

• Total synthesis and structure revision of the marine metabolite palmerolide A.

  Xin Jiang;Bo Liu;Sylvain Lebreton;Jef K. De Brabander

  138
  Citations

• Synthesis of the First Members of a New Class of Biologically Active Bryostatin Analogues

  PA Wender;J De Brabander;PG Harran;JM Jimenez

  137
  Citations

• Total Synthesis and Initial Structure−Function Analysis of the Potent V-ATPase Inhibitors Salicylihalamide A and Related Compounds

  Yusheng Wu;Xibin Liao;Ruifang Wang;Xiao Song Xie

  108
  Citations

• Synthesis of side chain truncated apicularen A

  Ashoke Bhattacharjee;Jef K De Brabander

  105
  Citations

• Vacuolar ATPase in Phagosome-Lysosome Fusion

  Sandra Kissing;Christina Hermsen;Urska Repnik;Cecilie Kåsi Nesset

  105
  Citations

• Studies toward the unique pederin family member psymberin: full structure elucidation, two alternative total syntheses, and analogs.

  Yu Feng;Xin Jiang;Jef K. De Brabander

  104
  Citations

• Revision of the Absolute Configuration of Salicylihalamide A through Asymmetric Total Synthesis

  Yusheng Wu;Lothar Esser;Jef K. De Brabander

  103
  Citations

• Au(I)- and Pt(II)-Catalyzed Cycloetherification of ω-Hydroxy Propargylic Esters

  Jef K. De Brabander;Bo Liu;Mingxing Qian

  93
  Citations

• Synthesis of Psymberin Analogues: Probing a Functional Correlation with the Pederin/Mycalamide Family of Natural Products

  Xin Jiang;Noelle Williams;Jef K. De Brabander

  92
  Citations

• Total synthesis of the macrolide (+)-aspicilin by an asymmetrically catalyzed macrocyclization of an ω-Alkynal ester

  Wolfgang Oppolzer;Rumen N. Radinov;Jef K De Brabander

  88
  Citations

• SAR Based Optimization of a 4-Quinoline Carboxylic Acid Analog with Potent Anti-Viral Activity.

  Priyabrata Das;Xiaoyi Deng;Liang Zhang;Michael G Roth

  80
  Citations