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Jef K. De Brabander

D-Index & Metrics

Chemistry

D-Index
41
Citations
7303
World Ranking
17706
National Ranking
4323

Jef K. De Brabander publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where Jef K. De Brabander sits on this spectrum.

61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61 publications 1,295+

This scientist: 142 publications — 11th percentile

11% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

Jef K. De Brabander D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Jef K. De Brabander sits on this spectrum.

40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40 D-Index 159+

This scientist: 41 D-Index — 2nd percentile

2% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

Overview

Jef K. De Brabander is affiliated with The University of Texas Southwestern Medical Center in the United States. Their research spans multiple areas within biochemistry, genetics, molecular biology, medicine, and neuroscience, with a focus on molecular biology and oncology among other subfields.

The main fields of study for this researcher include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine
  • Neuroscience

Within these broader fields, their subfields of study cover:

  • Molecular Biology
  • Oncology
  • Cognitive Neuroscience
  • Surgery
  • Endocrine and Autonomic Systems

Their work addresses a range of topics, primarily:

  • Sleep and Wakefulness Research
  • Ubiquitin and proteasome pathways
  • Cholesterol and Lipid Metabolism
  • Circadian rhythm and melatonin
  • Autophagy in Disease and Therapy
  • RNA modifications and cancer
  • RNA and protein synthesis mechanisms

Recent publications by Jef K. De Brabander include:

  • Structural basis for itraconazole-mediated NPC1 inhibition, 2020, Nature Communications
  • TK216 targets microtubules in Ewing sarcoma cells, 2022, Cell chemical biology
  • A Medicinal Chemistry-Driven Approach Identified the Sterol Isomerase EBP as the Molecular Target of TASIN Colorectal Cancer Toxins, 2020, Journal of the American Chemical Society
  • Molecular mechanism of the wake-promoting agent TAK-925, 2022, Nature Communications
  • Selective and brain-penetrant lanosterol synthase inhibitors target glioma stem-like cells by inducing 24(S),25-epoxycholesterol production, 2023, Cell chemical biology

Frequent co-authors working alongside Jef K. De Brabander are:

  • Deepak Nijhawan
  • Noelle S. Williams
  • Jiwoong Kim
  • Rameshu Rallabandi
  • Juan Manuel Povedano

Their publications are often found in these venues:

  • Cell chemical biology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Journal of Medicinal Chemistry
  • ACS Chemical Biology

Best Publications

  • A Small Molecule Smac Mimic Potentiates TRAIL- and TNFα-Mediated Cell Death

    Lin Li;Ranny Mathew Thomas;Hidetaka Suzuki;Jef K. De Brabander

  • Cholesterol and 25-Hydroxycholesterol Inhibit Activation of SREBPs by Different Mechanisms, Both Involving SCAP and Insigs

    Christopher M. Adams;Julian Reitz;Jef K. De Brabander;Jamison D. Feramisco

  • Identification of NPC1 as the target of U18666A, an inhibitor of lysosomal cholesterol export and Ebola infection

    Feiran Lu;Qiren Liang;Lina Abi-Mosleh;Akash Das

  • Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma

    Yufeng Shi;S. Kyun Lim;Qiren Liang;Swathi V. Iyer

  • Metal-catalyzed regioselective oxy-functionalization of internal alkynes: an entry into ketones, acetals, and spiroketals.

    Bo Liu;Jef K. De Brabander

  • Development of Proneurogenic, Neuroprotective Small Molecules

    Karen S. MacMillan;Jacinth Naidoo;Jue Liang;Lisa Melito

  • Total Synthesis and Absolute Configuration of the Novel Microtubule‐Stabilizing Agent Peloruside A

    Xibin Liao;Yusheng Wu;Jef K. De Brabander

  • Lessons and revelations from biomimetic syntheses

    Mina Razzak;Jef K De Brabander

  • Salicylihalamide A inhibits the V0 sector of the V-ATPase through a mechanism distinct from bafilomycin A1.

    Xiao Song Xie;David Padron;Xibin Liao;Jin Wang

  • Synthesis and Complete Stereochemical Assignment of Psymberin/Irciniastatin A

    Xin Jiang;Jorge Garcia-Fortanet;Jef K. De Brabander

  • Total synthesis and structure revision of the marine metabolite palmerolide A.

    Xin Jiang;Bo Liu;Sylvain Lebreton;Jef K. De Brabander

  • Synthesis of the First Members of a New Class of Biologically Active Bryostatin Analogues

    PA Wender;J De Brabander;PG Harran;JM Jimenez

  • Total Synthesis and Initial Structure−Function Analysis of the Potent V-ATPase Inhibitors Salicylihalamide A and Related Compounds

    Yusheng Wu;Xibin Liao;Ruifang Wang;Xiao Song Xie

  • Synthesis of side chain truncated apicularen A

    Ashoke Bhattacharjee;Jef K De Brabander

  • Vacuolar ATPase in Phagosome-Lysosome Fusion

    Sandra Kissing;Christina Hermsen;Urska Repnik;Cecilie Kåsi Nesset

  • Studies toward the unique pederin family member psymberin: full structure elucidation, two alternative total syntheses, and analogs.

    Yu Feng;Xin Jiang;Jef K. De Brabander

  • Revision of the Absolute Configuration of Salicylihalamide A through Asymmetric Total Synthesis

    Yusheng Wu;Lothar Esser;Jef K. De Brabander

  • Au(I)- and Pt(II)-Catalyzed Cycloetherification of ω-Hydroxy Propargylic Esters

    Jef K. De Brabander;Bo Liu;Mingxing Qian

  • Synthesis of Psymberin Analogues: Probing a Functional Correlation with the Pederin/Mycalamide Family of Natural Products

    Xin Jiang;Noelle Williams;Jef K. De Brabander

  • Total synthesis of the macrolide (+)-aspicilin by an asymmetrically catalyzed macrocyclization of an ω-Alkynal ester

    Wolfgang Oppolzer;Rumen N. Radinov;Jef K De Brabander

  • SAR Based Optimization of a 4-Quinoline Carboxylic Acid Analog with Potent Anti-Viral Activity.

    Priyabrata Das;Xiaoyi Deng;Liang Zhang;Michael G Roth

Frequent Co-Authors

Noelle S. Williams
Noelle S. Williams The University of Texas Southwestern Medical Center
Michael G. Roth
Michael G. Roth The University of Texas Southwestern Medical Center
Ilkka Julkunen
Ilkka Julkunen University of Turku
Steven L. McKnight
Steven L. McKnight The University of Texas Southwestern Medical Center
Wolfgang Oppolzer
Wolfgang Oppolzer University of Geneva
Xavier Saelens
Xavier Saelens Ghent University
Jerry W. Shay
Jerry W. Shay The University of Texas Southwestern Medical Center
Margaret A. Phillips
Margaret A. Phillips The University of Texas Southwestern Medical Center
Michael A. White
Michael A. White Ideaya Biosciences (United States)
Sampsa Matikainen
Sampsa Matikainen University of Helsinki

External Links

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Best Scientists Citing Jef K. De Brabander

Andrew A. Pieper

Andrew A. Pieper

University of Iowa

Publications: 34

John D. Minna

John D. Minna

The University of Texas Southwestern Medical Center

Publications: 27

Shaomeng Wang

Shaomeng Wang

University of Michigan–Ann Arbor

Publications: 27

Michael J. Krische

Michael J. Krische

The University of Texas at Austin

Publications: 26

John Silke

John Silke

Walter and Eliza Hall Institute of Medical Research

Publications: 24

Ermei Mäkilä

Ermei Mäkilä

University of Turku

Publications: 21

Yusuf Yagci

Yusuf Yagci

Istanbul Technical University

Publications: 20

Joseph L. Goldstein

Joseph L. Goldstein

The University of Texas Southwestern Medical Center

Publications: 20

Robert G. Korneluk

Robert G. Korneluk

University of Ottawa

Publications: 19

Simone Fulda

Simone Fulda

Goethe University Frankfurt

Publications: 19

Michael S. Brown

Michael S. Brown

The University of Texas Southwestern Medical Center

Publications: 19

Noelle S. Williams

Noelle S. Williams

The University of Texas Southwestern Medical Center

Publications: 18

Magnar Bjørås

Magnar Bjørås

Norwegian University of Science and Technology

Publications: 18

Hélder A. Santos

Hélder A. Santos

University Medical Center Groningen

Publications: 16

Alois Fürstner

Alois Fürstner

Max Planck Society

Publications: 16

Jouni Hirvonen

Jouni Hirvonen

University of Helsinki

Publications: 15

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