Shaomeng Wang

Further development and validation of empirical scoring functions for structure-based binding affinity prediction

Renxiao Wang;Luhua Lai;Shaomeng Wang.
Journal of Computer-aided Molecular Design (2002)

Comparative evaluation of 11 scoring functions for molecular docking.

Renxiao Wang;Yipin Lu;Shaomeng Wang.
Journal of Medicinal Chemistry (2003)

The PDBbind database: collection of binding affinities for protein-ligand complexes with known three-dimensional structures.

Renxiao Wang;Xueliang Fang;Yipin Lu;Shaomeng Wang.
Journal of Medicinal Chemistry (2004)

Therapeutic targeting of BET bromodomain proteins in castration-resistant prostate cancer

Irfan A. Asangani;Vijaya L. Dommeti;Xiaoju Wang;Rohit Malik.
Nature (2014)

Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition

Sanjeev Shangary;Dongguang Qin;Donna McEachern;Meilan Liu.
Proceedings of the National Academy of Sciences of the United States of America (2008)

Structure-Based Design of Spiro-oxindoles as Potent, Specific Small-Molecule Inhibitors of the MDM2−p53 Interaction

Ke Ding;Yipin Lu;Zaneta Nikolovska-Coleska;Guoping Wang.
Journal of Medicinal Chemistry (2006)

Structure-Based Design of Potent Non-Peptide MDM2 Inhibitors

Ke Ding;Yipin Lu;Zaneta Nikolovska-Coleska;Su Qiu.
Journal of the American Chemical Society (2005)

Small-molecule inhibitors of the MDM2-p53 protein-protein interaction to reactivate p53 function: a novel approach for cancer therapy.

Sanjeev Shangary;Shaomeng Wang.
Annual Review of Pharmacology and Toxicology (2009)

The PDBbind database: methodologies and updates.

Renxiao Wang;Xueliang Fang;Yipin Lu;Chao Yie Yang.
Journal of Medicinal Chemistry (2005)

Endocrine-therapy-resistant ESR1 variants revealed by genomic characterization of breast-cancer-derived xenografts.

Shunqiang Li;Dong Shen;Jieya Shao;Robert Crowder.
Cell Reports (2013)