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Chemistry

D-Index
72
Citations
17804
World Ranking
5276
National Ranking
1645

Overview

Amy Hauck Newman is affiliated with the National Institutes of Health in the United States. Their research spans the fields of Biochemistry, Genetics and Molecular Biology and Neuroscience, with specific focus on Molecular Biology, Cellular and Molecular Neuroscience, Pharmacology, Neurology, and Computational Theory and Mathematics.

The scientist's work extensively covers topics such as Receptor Mechanisms and Signaling, Neurotransmitter Receptor Influence on Behavior, Neuroscience and Neuropharmacology Research, Neuropeptides and Animal Physiology, Pharmacological Receptor Mechanisms and Effects, Computational Drug Discovery Methods, and Nicotinic Acetylcholine Receptors Study.

Some of the recent papers authored or coauthored by Amy Hauck Newman include:

  • New Drugs, Old Targets: Tweaking the Dopamine System to Treat Psychostimulant Use Disorders, 2021, The Annual Review of Pharmacology and Toxicology
  • Synaptic-like axo-axonal transmission from striatal cholinergic interneurons onto dopaminergic fibers, 2022, Neuron
  • The antidepressant drug vilazodone is an allosteric inhibitor of the serotonin transporter, 2021, Nature Communications
  • Dopamine D3 receptor-based medication development for the treatment of opioid use disorder: Rationale, progress, and challenges, 2020, Neuroscience & Biobehavioral Reviews
  • Preferential Gs protein coupling of the galanin Gal1 receptor in the µ-opioid-Gal1 receptor heterotetramer, 2022, Pharmacological Research

Their collaborations involve frequent coauthors including Alessandro Bonifazi, Gisela Andrea Camacho-Hernandez, Jianjing Cao, Zheng-Xiong Xi, and Lei Shi, reflecting multidisciplinary teamwork in their field.

Research publications by Amy Hauck Newman appear consistently in several prominent scientific venues. The frequent publication outlets include Journal of Medicinal Chemistry, bioRxiv (Cold Spring Harbor Laboratory), Journal of Pharmacology and Experimental Therapeutics, ACS Chemical Neuroscience, and ACS Pharmacology & Translational Science.

Best Publications

  • Structure of the human dopamine d3 receptor in complex with a d2/d3 selective antagonist.

    Ellen Y. T. Chien;Wei Liu;Qiang Zhao;Vsevolod Katritch

  • Genetic basis for species vulnerability in the Cheetah

    Stephen J. O'Brien;M. E. Roelke;L. Marker;A. Newman

  • The binding sites for cocaine and dopamine in the dopamine transporter overlap

    Thijs Beuming;Julie Kniazeff;Marianne L Bergmann;Lei Shi

  • Time-resolved FRET between GPCR ligands reveals oligomers in native tissues

    Laura Albizu;Martin Cottet;Martin Cottet;Martin Cottet;Michaela Kralikova;Stoytcho Stoev

  • Current perspectives on selective dopamine D(3) receptor antagonists as pharmacotherapeutics for addictions and related disorders.

    Christian A. Heidbreder;Amy H. Newman

  • Cooperative transcription activation by Nurr1 and Pitx3 induces embryonic stem cell maturation to the midbrain dopamine neuron phenotype

    Cecile Martinat;Jean-Jacques Bacci;Thomas Leete;Jongpil Kim

  • Tyr-95 and Ile-172 in Transmembrane Segments 1 and 3 of Human Serotonin Transporters Interact to Establish High Affinity Recognition of Antidepressants

    L. Keith Henry;Julie R. Field;Erika M. Adkins;M. Laura Parnas

  • Molecular determinants of selectivity and efficacy at the dopamine D3 receptor

    Amy Hauck Newman;Thijs Beuming;Ashwini K. Banala;Prashant Donthamsetti

  • The novel dopamine D3 receptor antagonist NGB 2904 inhibits cocaine's rewarding effects and cocaine-induced reinstatement of drug-seeking behavior in rats.

    Zheng-Xiong Xi;Amy Hauck Newman;Jeremy G Gilbert;Arlene C Pak

  • Medication discovery for addiction: translating the dopamine D3 receptor hypothesis.

    Amy Hauck Newman;Brandi L. Blaylock;Michael A. Nader;Jack Bergman

  • Missense dopamine transporter mutations associate with adult parkinsonism and ADHD

    Freja H. Hansen;Tina Skjørringe;Saiqa Yasmeen;Natascha V. Arends

  • The neurobiology of modafinil as an enhancer of cognitive performance and a potential treatment for substance use disorders

    Maddalena Mereu;Antonello Bonci;Amy Hauck Newman;Gianluigi Tanda

  • Dopamine Agonist-Induced Yawning in Rats: A Dopamine D3 Receptor-Mediated Behavior

    Gregory T. Collins;Jeffrey M. Witkin;Amy H. Newman;Kjell A. Svensson

  • Dissociable Control of Impulsivity in Rats by Dopamine D2/3 Receptors in the Core and Shell Subregions of the Nucleus Accumbens

    Morgane Besson;David Belin;Ruth McNamara;David Eh Theobald

  • R-Modafinil (Armodafinil): A Unique Dopamine Uptake Inhibitor and Potential Medication for Psychostimulant Abuse

    Claus J. Loland;Maddalena Mereu;Oluyomi M. Okunola;Jianjing Cao

  • Acute administration of SB-277011A, NGB 2904, or BP 897 inhibits cocaine cue-induced reinstatement of drug-seeking behavior in rats: role of dopamine D3 receptors.

    Jeremy G. Gilbert;Amy Hauck Newman;Eliot L. Gardner;Charles R. Ashby

  • The N Terminus of Monoamine Transporters Is a Lever Required for the Action of Amphetamines

    Sonja Sucic;Stefan Dallinger;Barbara Zdrazil;Rene Weissensteiner

  • Relationship between Conformational Changes in the Dopamine Transporter and Cocaine-Like Subjective Effects of Uptake Inhibitors

    Claus J. Loland;Rajeev I. Desai;Mu Fa Zou;Jianjing Cao

  • Visualization of Dopamine Transporter Trafficking in Live Neurons by Use of Fluorescent Cocaine Analogs

    Jacob Eriksen;Søren G. F. Rasmussen;Trine Nygaard Rasmussen;Christian Bjerggaard Vaegter

  • σ Receptors negatively modulate agonist-stimulated phosphoinositide metabolism in rat brain

    Wayne D. Bowen;Brian K. Kirschner;Amy H. Newman;Kenner C. Rice

Frequent Co-Authors

Jonathan L. Katz
Jonathan L. Katz National Institute on Drug Abuse
Gianluigi Tanda
Gianluigi Tanda National Institutes of Health
Lei Shi
Lei Shi National Institute on Drug Abuse
Zheng-Xiong Xi
Zheng-Xiong Xi National Institutes of Health
Kenner C. Rice
Kenner C. Rice National Institutes of Health
Ulrik Gether
Ulrik Gether University of Copenhagen
Eliot L. Gardner
Eliot L. Gardner National Institute on Drug Abuse
Harald H. Sitte
Harald H. Sitte Medical University of Vienna
Jonathan A. Javitch
Jonathan A. Javitch Columbia University
Barbara S. Slusher
Barbara S. Slusher Johns Hopkins University School of Medicine

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