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Biology and Biochemistry

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115
Citations
39232
World Ranking
806
National Ranking
507

Medicine

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114
Citations
38942
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Research.com Recognitions

  • 2017 - Fellow, National Academy of Inventors

Overview

Randy D. Blakely is affiliated with Florida Atlantic University in the United States and conducts research primarily in the fields of Neuroscience, Biochemistry, Genetics and Molecular Biology, and Medicine.

Their research focuses extensively on specialized subfields including Cellular and Molecular Neuroscience, Molecular Biology, Cognitive Neuroscience, Physiology, and Nephrology.

Key topics addressed in their work include:

  • Neurotransmitter Receptor Influence on Behavior
  • Receptor Mechanisms and Signaling
  • Neuroscience and Neuropharmacology Research
  • Autism Spectrum Disorder Research
  • Genetics, Aging, and Longevity in Model Organisms
  • Tryptophan and brain disorders
  • Neuroendocrine regulation and behavior

Recent papers authored by this researcher are:

  • "Regulation of autism-relevant behaviors by cerebellar-prefrontal cortical circuits," 2020, Nature Neuroscience
  • "Gαo is a major determinant of cAMP signaling in the pathophysiology of movement disorders," 2021, Cell Reports
  • "Inflammation-Induced Histamine Impairs the Capacity of Escitalopram to Increase Hippocampal Extracellular Serotonin," 2021, Journal of Neuroscience
  • "Neurobehavioral changes arising from early life dopamine signaling perturbations," 2020, Neurochemistry International
  • "Serotonin-releasing agents with reduced off-target effects," 2022, Molecular Psychiatry

Frequent coauthors in their publications include:

  • Felix P. Mayer
  • Marco Niello
  • Julian Maier
  • Marko D. Mihovilovič
  • Harald H. Sitte

Common publication venues for their work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Zenodo (CERN European Organization for Nuclear Research)
  • Molecular Psychiatry
  • Journal of Neuroscience
  • Neurochemistry International

Randy D. Blakely has been recognized as a Fellow of the National Academy of Inventors since 2017.

Best Publications

  • Expression cloning of a cocaine- and antidepressant-sensitive human noradrenaline transporter.

    Tadeusz Pacholczyk;Randy D. Blakely;Randy D. Blakely;Susan G. Amara

  • Antidepressant- and cocaine-sensitive human serotonin transporter: molecular cloning, expression, and chromosomal localization.

    Sammanda Ramamoorthy;Andrea L. Bauman;Kim R. Moore;Hong Han

  • Pharmacological profile of antidepressants and related compounds at human monoamine transporters.

    Masahiko Tatsumi;Karen Groshan;Randy D Blakely;Elliott Richelson

  • Cloning and expression of a functional serotonin transporter from rat brain.

    Randy D. Blakely;Haley E. Berson;Robert T. Fremeau;Marc G. Caron

  • A transient placental source of serotonin for the fetal forebrain

    Alexandre Bonnin;Nick Goeden;Kevin Chen;Melissa L. Wilson

  • The proinflammatory cytokines interleukin-1beta and tumor necrosis factor-alpha activate serotonin transporters

    Chong-Bin Zhu;Randy D Blakely;William A Hewlett

  • Orthostatic Intolerance and Tachycardia Associated with Norepinephrine-Transporter Deficiency

    John R. Shannon;Nancy L. Flattem;Jens Jordan;Giris Jacob

  • MOLECULAR PHYSIOLOGY OF NOREPINEPHRINE AND SEROTONIN TRANSPORTERS

    R D Blakely;L J De Felice;H C Hartzell

  • Allelic heterogeneity at the serotonin transporter locus (SLC6A4) confers susceptibility to autism and rigid-compulsive behaviors

    James S. Sutcliffe;Ryan J. Delahanty;Harish C. Prasad;Jacob L. McCauley

  • Dopaminergic neuronal loss and motor deficits in Caenorhabditis elegans overexpressing human α‐synuclein

    Merja Lakso;Suvi Vartiainen;Anu Maarit Moilanen;Jouni Sirviö

  • Neurotoxin-induced degeneration of dopamine neurons in Caenorhabditis elegans

    Richard Nass;David H. Hall;David M. Miller;Randy D. Blakely

  • Targeting cell surface receptors with ligand-conjugated nanocrystals.

    Sandra J Rosenthal;Ian Tomlinson;Erika M Adkins;Sally Schroeter

  • Hydrolysis of the brain dipeptide N-acetyl-L-aspartyl-L-glutamate. Identification and characterization of a novel N-acetylated alpha-linked acidic dipeptidase activity from rat brain.

    M B Robinson;R D Blakely;R Couto;J T Coyle

  • Phosphorylation and sequestration of serotonin transporters differentially modulated by psychostimulants.

    Sammanda Ramamoorthy;Randy D. Blakely

  • Protein Kinase C Activation Regulates Human Serotonin Transporters in HEK-293 Cells via Altered Cell Surface Expression

    Yan Qian;Aurelio Galli;Sammanda Ramamoorthy;Stefania Risso

  • Localization and function of a 5-HT transporter in crypt epithelia of the gastrointestinal tract.

    PR Wade;J Chen;B Jaffe;IS Kassem

  • Immunolocalization of the cocaine- and antidepressant-sensitive l-norepinephrine transporter.

    Sally Schroeter;Subbu Apparsundaram;Ronald G. Wiley;Leeann H. Miner

  • Amphetamine induces dopamine efflux through a dopamine transporter channel

    Kristopher M. Kahlig;Francesca Binda;Habibeh Khoshbouei;Randy D. Blakely

  • Interleukin-1 receptor activation by systemic lipopolysaccharide induces behavioral despair linked to MAPK regulation of CNS serotonin transporters.

    Chong Bin Zhu;Kathryn M. Lindler;Anthony W. Owens;Lynette C. Daws

  • A Dialogue between the Immune System and Brain, Spoken in the Language of Serotonin

    Nicole L. Baganz;Randy D. Blakely

Frequent Co-Authors

Jeremy Veenstra-VanderWeele
Jeremy Veenstra-VanderWeele Columbia University
Sandra J. Rosenthal
Sandra J. Rosenthal Vanderbilt University
Louis J. DeFelice
Louis J. DeFelice Virginia Commonwealth University
Aurelio Galli
Aurelio Galli University of Alabama at Birmingham
Joseph T. Coyle
Joseph T. Coyle Harvard University
James S. Sutcliffe
James S. Sutcliffe Vanderbilt University
David Robertson
David Robertson Vanderbilt University
Martin Sarter
Martin Sarter University of Michigan–Ann Arbor
Michelle S. Mazei-Robison
Michelle S. Mazei-Robison Michigan State University
Susan G. Amara
Susan G. Amara National Institutes of Health

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