His primary scientific interests are in Virology, Antigen, Molecular biology, Mycobacterium tuberculosis and Immunology. In his work, Expression cloning and Pan-T antigens is strongly intertwined with Antigen presentation, which is a subfield of Virology. Mark R. Alderson has included themes like CD1, Natural killer T cell, T cell, Interleukin 21 and ZAP70 in his Molecular biology study.
His research in T cell focuses on subjects like Fas receptor, which are connected to Cell biology, Virus, Downregulation and upregulation, Blocking antibody and Jurkat cells. His Mycobacterium tuberculosis research focuses on subjects like Epitope, which are linked to Recombinant DNA. His Immunology research incorporates elements of Apoptosis and Fas ligand.
His primary areas of investigation include Virology, Immunology, Antigen, Microbiology and T cell. The concepts of his Virology study are interwoven with issues in Interferon gamma, MHC class I, Fusion protein, Mycobacterium tuberculosis and Epitope. His studies deal with areas such as Pneumococcal vaccine and Streptococcus pneumoniae as well as Immunology.
His studies examine the connections between Antigen and genetics, as well as such issues in Antibody, with regards to Interleukin 4. His work carried out in the field of Microbiology brings together such families of science as Chlamydia, Chlamydia trachomatis and Immunization. His T cell study combines topics in areas such as Molecular biology, Cytotoxic T cell, CD8 and Cell biology.
Immunology, Vaccination, Pneumococcal conjugate vaccine, Streptococcus pneumoniae and Reactogenicity are his primary areas of study. He combines Immunology and Whole cell in his research. Mark R. Alderson interconnects Adverse effect, Disease and Haemophilus influenzae in the investigation of issues within Vaccination.
His Pneumococcal conjugate vaccine research includes themes of Pediatrics, Immunogenicity and Toxoid. In his study, which falls under the umbrella issue of Streptococcus pneumoniae, Proteome is strongly linked to Immune system. His research in Virology is mostly concerned with Serotype.
Mark R. Alderson focuses on Immunology, Streptococcus pneumoniae, Reactogenicity, Antibody and Whole cell. His Immunology study incorporates themes from Pneumococcal conjugate vaccine and Pneumolysin. His study in Streptococcus pneumoniae focuses on Pneumococcal vaccine in particular.
His work deals with themes such as MenAfriVac, Meningococcal vaccine, Internal medicine, Intramuscular injection and Vaccination, which intersect with Reactogenicity. Mark R. Alderson combines subjects such as Infectious disease, Immune system, Genetically modified organism and Meningitis with his study of Antibody.
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Fas ligand mediates activation-induced cell death in human T lymphocytes.
M R Alderson;T W Tough;T Davis-Smith;S Braddy.
Journal of Experimental Medicine (1995)
CD40 expression by human monocytes: regulation by cytokines and activation of monocytes by the ligand for CD40.
M R Alderson;R J Armitage;T W Tough;L Strockbine.
Journal of Experimental Medicine (1993)
Interleukin 1 signaling occurs exclusively via the type I receptor.
J E Sims;M A Gayle;J L Slack;M R Alderson.
Proceedings of the National Academy of Sciences of the United States of America (1993)
Fas transduces activation signals in normal human T lymphocytes.
M R Alderson;R J Armitage;E Maraskovsky;T W Tough.
Journal of Experimental Medicine (1993)
Upregulation of Fas ligand expression by human immunodeficiency virus in human macrophages mediates apoptosis of uninfected T lymphocytes.
Andrew D. Badley;Julie A. McElhinny;Paul J. Leibson;David H. Lynch.
Journal of Virology (1996)
Differential immune responses and protective efficacy induced by components of a tuberculosis polyprotein vaccine, Mtb72F, delivered as naked DNA or recombinant protein.
Yasir A. W. Skeiky;Mark R. Alderson;Pamela J. Ovendale;Jeffrey A. Guderian.
Journal of Immunology (2004)
TH17-Based Vaccine Design for Prevention of Streptococcus pneumoniae Colonization
Kristin L. Moffitt;Todd M. Gierahn;Ying-jie Lu;Paulo Gouveia.
Cell Host & Microbe (2011)
Interleukin 7 induces cytokine secretion and tumoricidal activity by human peripheral blood monocytes.
M R Alderson;T W Tough;S F Ziegler;K H Grabstein.
Journal of Experimental Medicine (1991)
CHARACTERIZATION OF HUMAN CD8+ T CELLS REACTIVE WITH MYCOBACTERIUM TUBERCULOSIS-INFECTED ANTIGEN-PRESENTING CELLS
David M. Lewinsohn;David M. Lewinsohn;Mark R. Alderson;Andria L. Briden;Stanley R. Riddell.
Journal of Experimental Medicine (1998)
Molecular characterization of the early activation antigen CD69: A type II membrane glycoprotein related to a family of natural killer cell activation antigens
Steven F. Ziegler;Fred Ramsdell;Kathryn A. Hjerrild;Richard J. Armitage.
European Journal of Immunology (1993)
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