D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Microbiology D-index 47 Citations 9,798 85 World Ranking 3662 National Ranking 1454

Overview

What is he best known for?

The fields of study he is best known for:

  • Immune system
  • Gene
  • Antigen

His primary scientific interests are in Virology, Antigen, Molecular biology, Mycobacterium tuberculosis and Immunology. In his work, Expression cloning and Pan-T antigens is strongly intertwined with Antigen presentation, which is a subfield of Virology. Mark R. Alderson has included themes like CD1, Natural killer T cell, T cell, Interleukin 21 and ZAP70 in his Molecular biology study.

His research in T cell focuses on subjects like Fas receptor, which are connected to Cell biology, Virus, Downregulation and upregulation, Blocking antibody and Jurkat cells. His Mycobacterium tuberculosis research focuses on subjects like Epitope, which are linked to Recombinant DNA. His Immunology research incorporates elements of Apoptosis and Fas ligand.

His most cited work include:

  • Fas ligand mediates activation-induced cell death in human T lymphocytes. (853 citations)
  • CD40 expression by human monocytes: regulation by cytokines and activation of monocytes by the ligand for CD40. (561 citations)
  • Interleukin 1 signaling occurs exclusively via the type I receptor. (551 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Virology, Immunology, Antigen, Microbiology and T cell. The concepts of his Virology study are interwoven with issues in Interferon gamma, MHC class I, Fusion protein, Mycobacterium tuberculosis and Epitope. His studies deal with areas such as Pneumococcal vaccine and Streptococcus pneumoniae as well as Immunology.

His studies examine the connections between Antigen and genetics, as well as such issues in Antibody, with regards to Interleukin 4. His work carried out in the field of Microbiology brings together such families of science as Chlamydia, Chlamydia trachomatis and Immunization. His T cell study combines topics in areas such as Molecular biology, Cytotoxic T cell, CD8 and Cell biology.

He most often published in these fields:

  • Virology (38.82%)
  • Immunology (31.76%)
  • Antigen (34.12%)

What were the highlights of his more recent work (between 2016-2021)?

  • Immunology (31.76%)
  • Vaccination (17.65%)
  • Pneumococcal conjugate vaccine (8.24%)

In recent papers he was focusing on the following fields of study:

Immunology, Vaccination, Pneumococcal conjugate vaccine, Streptococcus pneumoniae and Reactogenicity are his primary areas of study. He combines Immunology and Whole cell in his research. Mark R. Alderson interconnects Adverse effect, Disease and Haemophilus influenzae in the investigation of issues within Vaccination.

His Pneumococcal conjugate vaccine research includes themes of Pediatrics, Immunogenicity and Toxoid. In his study, which falls under the umbrella issue of Streptococcus pneumoniae, Proteome is strongly linked to Immune system. His research in Virology is mostly concerned with Serotype.

Between 2016 and 2021, his most popular works were:

  • Efficacy of a novel, protein-based pneumococcal vaccine against nasopharyngeal carriage of Streptococcus pneumoniae in infants: A phase 2, randomized, controlled, observer-blind study (44 citations)
  • Safety and immunogenicity of a pentavalent meningococcal conjugate vaccine containing serogroups A, C, Y, W, and X in healthy adults: a phase 1, single-centre, double-blind, randomised, controlled study. (32 citations)
  • Maternal immunization against Group B streptococcus: World Health Organization research and development technological roadmap and preferred product characteristics (23 citations)

In his most recent research, the most cited papers focused on:

  • Immune system
  • Gene
  • Antibody

Mark R. Alderson focuses on Immunology, Streptococcus pneumoniae, Reactogenicity, Antibody and Whole cell. His Immunology study incorporates themes from Pneumococcal conjugate vaccine and Pneumolysin. His study in Streptococcus pneumoniae focuses on Pneumococcal vaccine in particular.

His work deals with themes such as MenAfriVac, Meningococcal vaccine, Internal medicine, Intramuscular injection and Vaccination, which intersect with Reactogenicity. Mark R. Alderson combines subjects such as Infectious disease, Immune system, Genetically modified organism and Meningitis with his study of Antibody.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Fas ligand mediates activation-induced cell death in human T lymphocytes.

M R Alderson;T W Tough;T Davis-Smith;S Braddy.
Journal of Experimental Medicine (1995)

1347 Citations

CD40 expression by human monocytes: regulation by cytokines and activation of monocytes by the ligand for CD40.

M R Alderson;R J Armitage;T W Tough;L Strockbine.
Journal of Experimental Medicine (1993)

904 Citations

Interleukin 1 signaling occurs exclusively via the type I receptor.

J E Sims;M A Gayle;J L Slack;M R Alderson.
Proceedings of the National Academy of Sciences of the United States of America (1993)

797 Citations

Fas transduces activation signals in normal human T lymphocytes.

M R Alderson;R J Armitage;E Maraskovsky;T W Tough.
Journal of Experimental Medicine (1993)

760 Citations

Upregulation of Fas ligand expression by human immunodeficiency virus in human macrophages mediates apoptosis of uninfected T lymphocytes.

Andrew D. Badley;Julie A. McElhinny;Paul J. Leibson;David H. Lynch.
Journal of Virology (1996)

440 Citations

Differential immune responses and protective efficacy induced by components of a tuberculosis polyprotein vaccine, Mtb72F, delivered as naked DNA or recombinant protein.

Yasir A. W. Skeiky;Mark R. Alderson;Pamela J. Ovendale;Jeffrey A. Guderian.
Journal of Immunology (2004)

416 Citations

TH17-Based Vaccine Design for Prevention of Streptococcus pneumoniae Colonization

Kristin L. Moffitt;Todd M. Gierahn;Ying-jie Lu;Paulo Gouveia.
Cell Host & Microbe (2011)

247 Citations

Interleukin 7 induces cytokine secretion and tumoricidal activity by human peripheral blood monocytes.

M R Alderson;T W Tough;S F Ziegler;K H Grabstein.
Journal of Experimental Medicine (1991)

241 Citations

CHARACTERIZATION OF HUMAN CD8+ T CELLS REACTIVE WITH MYCOBACTERIUM TUBERCULOSIS-INFECTED ANTIGEN-PRESENTING CELLS

David M. Lewinsohn;David M. Lewinsohn;Mark R. Alderson;Andria L. Briden;Stanley R. Riddell.
Journal of Experimental Medicine (1998)

215 Citations

Molecular characterization of the early activation antigen CD69: A type II membrane glycoprotein related to a family of natural killer cell activation antigens

Steven F. Ziegler;Fred Ramsdell;Kathryn A. Hjerrild;Richard J. Armitage.
European Journal of Immunology (1993)

201 Citations

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