D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 57 Citations 20,835 108 World Ranking 9158 National Ranking 4077

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Immune system
  • Cytokine

His primary scientific interests are in Apoptosis, Molecular biology, Fas receptor, Cell biology and Fas ligand. Many of his research projects under Apoptosis are closely connected to Tumor Necrosis Factor Decoy Receptors with Tumor Necrosis Factor Decoy Receptors, tying the diverse disciplines of science together. His biological study deals with issues like Cytotoxic T cell, which deal with fields such as Viral replication, Virology and Virus.

David H. Lynch works mostly in the field of Cell biology, limiting it down to topics relating to T cell and, in certain cases, Biochemistry and Cell surface receptor. The concepts of his Fas ligand study are interwoven with issues in Southern blot, Transfection, Point mutation, Complementary DNA and Gene cluster. In his work, Immune system is strongly intertwined with Cancer research, which is a subfield of Tumor necrosis factor alpha.

His most cited work include:

  • Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo (2225 citations)
  • Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas (1218 citations)
  • Induction of apoptosis in mature T cells by tumour necrosis factor. (1046 citations)

What are the main themes of his work throughout his whole career to date?

David H. Lynch focuses on Immunology, Molecular biology, Cell biology, Apoptosis and Cytotoxic T cell. His Immunology study frequently links to adjacent areas such as In vivo. His Molecular biology study also includes

  • T cell that intertwine with fields like Clone,
  • CD40 which is related to area like MHC class II.

His Cell biology research includes themes of Cell and Cell type. David H. Lynch has included themes like Tumor necrosis factor alpha and Receptor in his Apoptosis study. David H. Lynch combines subjects such as CD3 and Macrophage with his study of Cytotoxic T cell.

He most often published in these fields:

  • Immunology (49.07%)
  • Molecular biology (33.33%)
  • Cell biology (30.56%)

What were the highlights of his more recent work (between 1999-2009)?

  • Immunology (49.07%)
  • Apoptosis (28.70%)
  • Cell biology (30.56%)

In recent papers he was focusing on the following fields of study:

David H. Lynch spends much of his time researching Immunology, Apoptosis, Cell biology, Immune system and Molecular biology. In his study, Cell culture and Tumor necrosis factor alpha is inextricably linked to Jurkat cells, which falls within the broad field of Apoptosis. His research in the fields of Signal transduction overlaps with other disciplines such as Population.

David H. Lynch interconnects Cytotoxic T cell, Viral replication and Virology in the investigation of issues within Immune system. His Molecular biology study incorporates themes from In vitro, Progenitor cell, Dendritic cell homeostasis, Growth factor and APAF1. His biological study spans a wide range of topics, including In vivo, Lymphokine, CD8 and CD40.

Between 1999 and 2009, his most popular works were:

  • Mice lacking flt3 ligand have deficient hematopoiesis affecting hematopoietic progenitor cells, dendritic cells, and natural killer cells. (760 citations)
  • The CD95 receptor: apoptosis revisited. (345 citations)
  • Mechanisms of HIV-associated lymphocyte apoptosis. (277 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Cytokine

The scientist’s investigation covers issues in Immunology, Cell biology, Signal transduction, T lymphocyte and Virology. His studies deal with areas such as Progenitor cell, Cell, Haematopoiesis and FMS-like tyrosine kinase 3 ligand as well as Immunology. His Cell biology research is multidisciplinary, incorporating elements of Apoptosis, Receptor, Ligand and Fas receptor.

His Signal transduction research incorporates elements of HSL and HSV, Cell type and Chromosomal translocation. His studies in T lymphocyte integrate themes in fields like Cytotoxic T cell and Viral replication. He studies Virus which is a part of Virology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo

Henning Walczak;Robert E. Miller;Kiley Ariail;Brian Gliniak.
Nature Medicine (1999)

3015 Citations

Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas

Thomas Brunner;Rona J. Mogil;Drake LaFace;Nam Jin Yoo.
Nature (1995)

1647 Citations

Fas ligand mediates activation-induced cell death in human T lymphocytes.

M R Alderson;T W Tough;T Davis-Smith;S Braddy.
Journal of Experimental Medicine (1995)

1347 Citations

Induction of apoptosis in mature T cells by tumour necrosis factor.

Lixin Zheng;Galen Fisher;Robert E. Miller;Jacques Peschon.
Nature (1995)

1329 Citations

Mice lacking flt3 ligand have deficient hematopoiesis affecting hematopoietic progenitor cells, dendritic cells, and natural killer cells.

Hilary J. McKenna;Kim L. Stocking;Robert E. Miller;Kenneth Brasel.
Blood (2000)

1122 Citations

Intracellular Regulation of TRAIL-Induced Apoptosis in Human Melanoma Cells

Thomas S. Griffith;Wilson A. Chin;Glenn C. Jackson;David H. Lynch.
Journal of Immunology (1998)

900 Citations

Fas and FasL in the homeostatic regulation of immune responses.

David H. Lynch;Fred Ramsdell;Mark R. Alderson.
Immunology Today (1995)

834 Citations

Fas transduces activation signals in normal human T lymphocytes.

M R Alderson;R J Armitage;E Maraskovsky;T W Tough.
Journal of Experimental Medicine (1993)

760 Citations

TRAIL: a molecule with multiple receptors and control mechanisms

Thomas S Griffith;David H Lynch.
Current Opinion in Immunology (1998)

619 Citations

The CD95 receptor: apoptosis revisited.

Marcus E. Peter;Ralph C. Budd;Julie Desbarats;Stephen M. Hedrick.
Cell (2007)

457 Citations

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