David H. Lynch

Overview

Best Publications

• Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo

  Henning Walczak;Robert E. Miller;Kiley Ariail;Brian Gliniak

  3146
  Citations

• Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas

  Thomas Brunner;Rona J. Mogil;Drake LaFace;Nam Jin Yoo

  1666
  Citations

• Fas ligand mediates activation-induced cell death in human T lymphocytes.

  M R Alderson;T W Tough;T Davis-Smith;S Braddy

  1378
  Citations

• Induction of apoptosis in mature T cells by tumour necrosis factor.

  Lixin Zheng;Galen Fisher;Robert E. Miller;Jacques Peschon

  1353
  Citations

• Mice lacking flt3 ligand have deficient hematopoiesis affecting hematopoietic progenitor cells, dendritic cells, and natural killer cells.

  Hilary J. McKenna;Kim L. Stocking;Robert E. Miller;Kenneth Brasel

  1211
  Citations

• Intracellular Regulation of TRAIL-Induced Apoptosis in Human Melanoma Cells

  Thomas S. Griffith;Wilson A. Chin;Glenn C. Jackson;David H. Lynch

  908
  Citations

• Fas and FasL in the homeostatic regulation of immune responses.

  David H. Lynch;Fred Ramsdell;Mark R. Alderson

  830
  Citations

• Fas transduces activation signals in normal human T lymphocytes.

  M R Alderson;R J Armitage;E Maraskovsky;T W Tough

  765
  Citations

• TRAIL: a molecule with multiple receptors and control mechanisms

  Thomas S Griffith;David H Lynch

  623
  Citations

• The CD95 receptor: apoptosis revisited.

  Marcus E. Peter;Ralph C. Budd;Julie Desbarats;Stephen M. Hedrick

  489
  Citations

• Differential ability of Th1 and Th2 T cells to express Fas ligand and to undergo activation-induced cell death

  Fred Ramsdell;Michael S. Seaman;Robert E. Miller;Kathleen S. Picha

  479
  Citations

• Flt3 ligand induces tumor regression and antitumor immune responses in vivo

  David H. Lynch;Alice Andreasen;Eugene Maraskovsky;James Whitmore

  468
  Citations

• Upregulation of Fas ligand expression by human immunodeficiency virus in human macrophages mediates apoptosis of uninfected T lymphocytes.

  Andrew D. Badley;Julie A. McElhinny;Paul J. Leibson;David H. Lynch

  442
  Citations

• Mechanisms of HIV-associated lymphocyte apoptosis.

  Andrew D. Badley;André A. Pilon;André A. Pilon;Alan Landay;Alan Landay;David H. Lynch;David H. Lynch

  440
  Citations

• The mouse fas-ligand gene is mutated in gld mice and is part of a TNF family gene cluster

  David H. Lynch;Mark L. Watson;Mark R. Alderson;Peter R. Baum

  404
  Citations

• Fas ligand (CD95L) and B7 expression on dendritic cells provide counter-regulatory signals for T cell survival and proliferation.

  Lina Lu;Shiguang Qian;Pamela A. Hershberger;William A. Rudert

  358
  Citations

• Polyethylene Glycol-Modified GM-CSF Expands CD11bhighCD11chigh But Not CD11blowCD11chigh Murine Dendritic Cells In Vivo: A Comparative Analysis with Flt3 Ligand

  Elizabeth Daro;Bali Pulendran;Kenneth Brasel;Mark Teepe

  336
  Citations

• Functional Analysis of TRAIL Receptors Using Monoclonal Antibodies

  Thomas S. Griffith;Charles T. Rauch;Pam J. Smolak;Jennifer Y. Waugh

  331
  Citations

• Macrophage-dependent Apoptosis of CD4+ T Lymphocytes from HIV-infected Individuals Is Mediated by FasL and Tumor Necrosis Factor

  Andrew D. Badley;David Dockrell;Margaret Simpson;Ron Schut

  293
  Citations

• Quantitative measurement of nuclear translocation events using similarity analysis of multispectral cellular images obtained in flow.

  Thaddeus C. George;Stacey L. Fanning;Patricia Fitzgeral-Bocarsly;Ricardo B. Medeiros

  291
  Citations