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Andrew A. Somogyi

Andrew A. Somogyi

D-Index & Metrics

Medicine

D-Index
76
Citations
18589
World Ranking
18885
National Ranking
634

Overview

Andrew A. Somogyi is affiliated with the University of Adelaide in Australia and has contributed extensively to the field of medicine, with a strong focus on pharmacology and related disciplines. Their research spans multiple subfields including pharmacology, pediatrics, perinatology and child health, anesthesiology and pain medicine, surgery, and biological psychiatry.

Their main research topics encompass:

  • Treatment of Major Depression
  • Pain Management and Opioid Use
  • Tryptophan and Brain Disorders
  • Pharmacogenetics and Drug Metabolism
  • Pharmacological Effects and Toxicity Studies
  • Pediatric Pain Management Techniques
  • Mental Health Research Topics

Recent publications by Andrew A. Somogyi include:

  • Clinical Pharmacogenetics Implementation Consortium Guideline for CYP2D6, OPRM1, and COMT Genotypes and Select Opioid Therapy (2021, Clinical Pharmacology & Therapeutics)
  • PharmVar GeneFocus: CYP2B6 (2021, Clinical Pharmacology & Therapeutics)
  • Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2C9 and HLA-B Genotypes and Phenytoin Dosing: 2020 Update (2020, Clinical Pharmacology & Therapeutics)
  • Effect of Regular, Low-Dose, Extended-release Morphine on Chronic Breathlessness in Chronic Obstructive Pulmonary Disease (2022, JAMA)
  • Efficacy and Safety of a 4-Week Course of Repeated Subcutaneous Ketamine Injections for Treatment-Resistant Depression (KADS Study): Randomised Double-Blind Active-Controlled Trial (2023, The British Journal of Psychiatry)

Andrew A. Somogyi has published frequently in the following venues:

  • Clinical Pharmacology & Therapeutics
  • The British Journal of Psychiatry
  • Neuroscience Applied
  • British Journal of Clinical Pharmacology
  • Pain Medicine

Their frequent co-authors include Michael Berk, Anthony Rodgers, Colleen Loo, Nick Glozier, and Natalie Mills, each contributing to multiple collaborations.

Andrew A. Somogyi's research contributions focus on understanding the pharmacogenetic basis of drug response, pain management, and psychiatric disorders, reflected in their work on opioid therapy, pharmacogenetic guidelines, and depression treatments.

Best Publications

  • Morphine activates neuroinflammation in a manner parallel to endotoxin

    Xiaohui Wang;Lisa C. Loram;Khara Ramos;Armando J. de Jesus

  • Pharmacogenetics of opioids.

    Andrew A Somogyi;Daniel T Barratt;Janet K Coller

  • Proinflammatory cytokines oppose opioid-induced acute and chronic analgesia

    Mark R. Hutchinson;Benjamen D. Coats;Susannah S. Lewis;Yingning Zhang

  • Hyperalgesic responses in methadone maintenance patients

    Mark Doverty;Jason M. White;Andrew A. Somogyi;Felix Bochner

  • Reduction of metformin renal tubular secretion by cimetidine in man.

    A Somogyi;C Stockley;J Keal;P Rolan

  • Opioid Activation of Toll-Like Receptor 4 Contributes to Drug Reinforcement

    M. R. Hutchinson;A. L. Northcutt;T. Hiranita;X. Wang

  • Drug interactions with cimetidine.

    Andrew Somogyi;Roland Gugler

  • Mu receptor binding of some commonly used opioids and their metabolites.

    Zhao Rong Chen;Rodney J. Irvine;Andrew A. Somogyi;Felix Bochner

  • Clinical Pharmacogenetics Implementation Consortium Guideline for CYP2D6, OPRM1, and COMT Genotypes and Select Opioid Therapy.

    Kristine R. Crews;Andrew A. Monte;Rachel Huddart;Kelly E. Caudle

  • Acute Pain Management in Opioid-Tolerant Patients: A Growing Challenge:

    C. A. Huxtable;L. J. Roberts;A. A. Somogyi;A. A. Somogyi;P. E. Macintyre;P. E. Macintyre

  • Effects of Low-Dose and Very Low-Dose Ketamine among Patients with Major Depression: a Systematic Review and Meta-Analysis.

    Ying Xu;Maree Hackett;Gregory Carter;Colleen Loo

  • Placebo-controlled pilot trial testing dose titration and intravenous, intramuscular and subcutaneous routes for ketamine in depression

    C. K. Loo;V. Gálvez;V. Gálvez;E. O'Keefe;P. B. Mitchell;P. B. Mitchell

  • Does intraoperative ketamine attenuate inflammatory reactivity following surgery? A systematic review and meta-analysis.

    Ola Dale;Andrew A. Somogyi;Yibai Li;Thomas Sullivan

  • The disposition of morphine and its 3- and 6-glucuronide metabolites in humans and animals, and the importance of the metabolites to the pharmacological effects of morphine.

    Robert W. Milne;Roger L. Nation;Andrew A. Somogyi

  • Methadone N-demethylation in human liver microsomes: lack of stereoselectivity and involvement of CYP3A4.

    David J. R. Foster;Andrew A. Somogyi;Felix Bochner

  • PharmVar GeneFocus: CYP2D6.

    Zeruesenay Desta;Ahmed El-Boraie;Li Gong;Andrew A Somogyi

  • Pharmacokinetic interactions of cimetidine 1987.

    Andrew Somogyi;Andrew Somogyi;Murray Muirhead;Murray Muirhead

  • Attenuation of morphine-induced delirium in palliative care by substitution with infusion of oxycodone

    Ian Maddocks;Andrew Somogyi;Fay Abbott;Peter Hayball

  • Hyperalgesia in opioid-managed chronic pain and opioid-dependent patients.

    Justin L. Hay;Jason M. White;Felix Bochner;Felix Bochner;Andrew A. Somogyi;Andrew A. Somogyi

  • Methadone maintenance patients are cross-tolerant to the antinociceptive effects of morphine

    Mark Doverty;Andrew A Somogyi;Andrew A Somogyi;Jason M White;Felix Bochner;Felix Bochner

Frequent Co-Authors

Mark R. Hutchinson
Mark R. Hutchinson University of Adelaide
Roger L. Nation
Roger L. Nation Monash University
Michel Eichelbaum
Michel Eichelbaum University of Tübingen
Yoon K. Loke
Yoon K. Loke University of East Anglia
Colleen Loo
Colleen Loo University of New South Wales
Philip B. Mitchell
Philip B. Mitchell University of New South Wales
Linda R. Watkins
Linda R. Watkins University of Colorado Boulder
John D. Hayball
John D. Hayball University of South Australia
John O. Miners
John O. Miners Flinders University
Elizabeth J. Phillips
Elizabeth J. Phillips Vanderbilt University Medical Center

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