Tomohiro Yoshimoto

Overview

Best Publications

• Defective NK Cell Activity and Th1 Response in IL-18–Deficient Mice

  Kiyoshi Takeda;Hiroko Tsutsui;Tomohiro Yoshimoto;Osamu Adachi

  1345
  Citations

• IL-12 up-regulates IL-18 receptor expression on T cells, Th1 cells, and B cells: synergism with IL-18 for IFN-gamma production.

  Tomohiro Yoshimoto;Kiyoshi Takeda;Takashi Tanaka;Kazunobu Ohkusu

  1193
  Citations

• Interleukin-18 is a unique cytokine that stimulates both Th1 and Th2 responses depending on its cytokine milieu.

  Kenji Nakanishi;Tomohiro Yoshimoto;Hiroko Tsutsui;Haruki Okamura

  917
  Citations

• Regulation of interferon-gamma production by IL-12 and IL-18

  Haruki Okamura;Shin-ichiro Kashiwamura;Hiroko Tsutsui;Tomohiro Yoshimoto

  779
  Citations

• Basophils contribute to T(H)2-IgE responses in vivo via IL-4 production and presentation of peptide-MHC class II complexes to CD4+ T cells.

  Tomohiro Yoshimoto;Koubun Yasuda;Hidehisa Tanaka;Masakiyo Nakahira

  743
  Citations

• INTERLEUKIN-18: A NOVEL CYTOKINE THAT AUGMENTS BOTH INNATE AND ACQUIRED IMMUNITY

  Haruki Okamura;Hiroko Tsutsui;Shin-Ichiro Kashiwamura;Tomohiro Yoshimoto

  702
  Citations

• Administration of IL-33 induces airway hyperresponsiveness and goblet cell hyperplasia in the lungs in the absence of adaptive immune system

  Yuichi Kondo;Tomohiro Yoshimoto;Koubun Yasuda;Shizue Futatsugi-Yumikura

  681
  Citations

• IL-18, although antiallergic when administered with IL-12, stimulates IL-4 and histamine release by basophils

  Tomohiro Yoshimoto;Hiroko Tsutsui;Kouji Tominaga;Katsuaki Hoshino

  635
  Citations

• Skin-specific expression of IL-33 activates group 2 innate lymphoid cells and elicits atopic dermatitis-like inflammation in mice

  Yasutomo Imai;Koubun Yasuda;Yoshiko Sakaguchi;Takashi Haneda

  544
  Citations

• Interleukin 18 together with interleukin 12 inhibits IgE production by induction of interferon-γ production from activated B cells

  Tomohiro Yoshimoto;Haruki Okamura;Yoh Ichi Tagawa;Yoichiro Iwakura

  524
  Citations

• Contribution of IL-33–activated type II innate lymphoid cells to pulmonary eosinophilia in intestinal nematode-infected mice

  Koubun Yasuda;Taichiro Muto;Tatsukata Kawagoe;Makoto Matsumoto

  367
  Citations

• Propionibacterium acnes treatment diminishes CD4+ NK1.1+ T cells but induces type I T cells in the liver by induction of IL-12 and IL-18 production from Kupffer cells.

  K Matsui;T Yoshimoto;H Tsutsui;Y Hyodo

  296
  Citations

• IL-27 Suppresses Th2 Cell Development and Th2 Cytokines Production from Polarized Th2 Cells: A Novel Therapeutic Way for Th2-Mediated Allergic Inflammation

  Tomohiro Yoshimoto;Takayuki Yoshimoto;Koubun Yasuda;Junichiro Mizuguchi

  279
  Citations

• A critical role of IL-33 in experimental allergic rhinitis.

  Yoko Haenuki;Kazufumi Matsushita;Shizue Futatsugi-Yumikura;Ken J. Ishii

  270
  Citations

• SOCS-1/SSI-1-Deficient NKT Cells Participate in Severe Hepatitis through Dysregulated Cross-Talk Inhibition of IFN-γ and IL-4 Signaling In Vivo

  Tetsuji Naka;Hiroko Tsutsui;Minoru Fujimoto;Yoshinori Kawazoe

  219
  Citations

• Association of serum interleukin-33 level and the interleukin-33 genetic variant with Japanese cedar pollinosis.

  M Sakashita;T Yoshimoto;T Hirota;M Harada

  211
  Citations

• Mast Cells Are Crucial for Induction of Group 2 Innate Lymphoid Cells and Clearance of Helminth Infections

  Chikako Shimokawa;Takashi Kanaya;Masami Hachisuka;Kenji Ishiwata

  193
  Citations

• T helper 1 cells stimulated with ovalbumin and IL-18 induce airway hyperresponsiveness and lung fibrosis by IFN-γ and IL-13 production

  Nobuki Hayashi;Tomohiro Yoshimoto;Kenji Izuhara;Kiyoshi Matsui

  185
  Citations

• Interleukin 18 Acts on Memory T Helper Cells Type 1 to Induce Airway Inflammation and Hyperresponsiveness in a Naive Host Mouse

  Takaaki Sugimoto;Yuriko Ishikawa;Tomohiro Yoshimoto;Nobuki Hayashi

  159
  Citations

• Interferon-gamma is a therapeutic target molecule for prevention of postoperative adhesion formation.

  Hisashi Kosaka;Tomohiro Yoshimoto;Takayuki Yoshimoto;Jiro Fujimoto

  152
  Citations