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Hiroko Tsutsui

D-Index & Metrics

Discipline name D-Index World Ranking Current World Ranking National Ranking Current National Ranking Publications Citations
Immunology 69 2465 2264 96 88 219 30029

Hiroko Tsutsui publications per year

The chart shows the history of publications by Hiroko Tsutsui between 1981 and 2025, highlighting the no. of papers published in each year and offering an overview of the publication velocity of this scholar. Hiroko Tsutsui published across 45 years, from 1981 to 2025, averaging 5 papers a year. Output peaked at 14 publications in 2010. 3 of the 226 publications appeared in the last two years.

No. of publications
5 10
Bar chart. Horizontal axis: year, 1981 to 2025. Vertical axis: number of publications, 0 to 14. Peak 14 publications in 2010. 1981: 1 publication 1982: 6 publications 1983: 13 publications 1984: 12 publications 1985: 12 publications 1986: 8 publications 1987: 7 publications 1988: 3 publications 1989: 2 publications 1990: 3 publications 1991: 3 publications 1992: 1 publication 1993: 6 publications 1994: 1 publication 1995: 3 publications 1996: 1 publication 1997: 4 publications 1998: 6 publications 1999: 12 publications 2000: 3 publications 2001: 8 publications 2002: 9 publications 2003: 8 publications 2004: 11 publications 2005: 8 publications 2006: 7 publications 2007: 5 publications 2008: 3 publications 2009: 3 publications 2010: 14 publications 2011: 5 publications 2012: 5 publications 2013: 4 publications 2014: 5 publications 2015: 4 publications 2016: 3 publications 2017: 4 publications 2018: 0 publications 2019: 6 publications 2020: 1 publication 2021: 2 publications 2022: 0 publications 2023: 1 publication 2024: 1 publication 2025: 2 publications
1981 2025

226 publications in total across all disciplines

View publications per year as a table
Hiroko Tsutsui: publications per year, 1981 to 2025
Year Publications
1981 1
1982 6
1983 13
1984 12
1985 12
1986 8
1987 7
1988 3
1989 2
1990 3
1991 3
1992 1
1993 6
1994 1
1995 3
1996 1
1997 4
1998 6
1999 12
2000 3
2001 8
2002 9
2003 8
2004 11
2005 8
2006 7
2007 5
2008 3
2009 3
2010 14
2011 5
2012 5
2013 4
2014 5
2015 4
2016 3
2017 4
2018 0
2019 6
2020 1
2021 2
2022 0
2023 1
2024 1
2025 2
Total 226
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Hiroko Tsutsui publication distribution in Immunology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Immunology in 2026. The highlighted bar marks where Hiroko Tsutsui sits on this spectrum.

No. of scientists
50 100 150
Bar chart with 76 bars. Horizontal axis: publications, 62–71 to 807+. Vertical axis: number of scientists, 0 to 189. Most scientists, 189, have 152–161 publications. The last bar groups every scientist with 807 publications or more. The highlighted bar, 212–221 publications, is where this scientist sits. 62–71 publications: 9 scientists 72–81 publications: 23 scientists 82–91 publications: 40 scientists 92–101 publications: 72 scientists 102–111 publications: 86 scientists 112–121 publications: 108 scientists 122–131 publications: 150 scientists 132–141 publications: 160 scientists 142–151 publications: 159 scientists 152–161 publications: 189 scientists 162–171 publications: 166 scientists 172–181 publications: 181 scientists 182–191 publications: 188 scientists 192–201 publications: 187 scientists 202–211 publications: 178 scientists 212–221 publications: 158 scientists 222–231 publications: 168 scientists 232–241 publications: 159 scientists 242–251 publications: 160 scientists 252–261 publications: 148 scientists 262–271 publications: 116 scientists 272–281 publications: 125 scientists 282–291 publications: 115 scientists 292–301 publications: 111 scientists 302–311 publications: 95 scientists 312–321 publications: 97 scientists 322–331 publications: 97 scientists 332–341 publications: 99 scientists 342–351 publications: 96 scientists 352–361 publications: 69 scientists 362–371 publications: 76 scientists 372–381 publications: 71 scientists 382–391 publications: 71 scientists 392–401 publications: 62 scientists 402–411 publications: 54 scientists 412–421 publications: 41 scientists 422–431 publications: 63 scientists 432–441 publications: 53 scientists 442–451 publications: 31 scientists 452–461 publications: 42 scientists 462–471 publications: 40 scientists 472–481 publications: 29 scientists 482–491 publications: 34 scientists 492–501 publications: 30 scientists 502–511 publications: 23 scientists 512–521 publications: 41 scientists 522–531 publications: 29 scientists 532–541 publications: 28 scientists 542–551 publications: 16 scientists 552–561 publications: 18 scientists 562–571 publications: 18 scientists 572–581 publications: 17 scientists 582–591 publications: 17 scientists 592–601 publications: 17 scientists 602–611 publications: 19 scientists 612–621 publications: 13 scientists 622–631 publications: 12 scientists 632–641 publications: 11 scientists 642–651 publications: 16 scientists 652–661 publications: 9 scientists 662–671 publications: 5 scientists 672–681 publications: 13 scientists 682–691 publications: 12 scientists 692–701 publications: 6 scientists 702–711 publications: 6 scientists 712–721 publications: 9 scientists 722–731 publications: 9 scientists 732–741 publications: 6 scientists 742–751 publications: 11 scientists 752–761 publications: 10 scientists 762–771 publications: 7 scientists 772–781 publications: 12 scientists 782–791 publications: 7 scientists 792–801 publications: 5 scientists 802–806 publications: 1 scientist 807+ publications: 100 scientists
62–71 publications 807+

This scientist: 219 publications — 41st percentile

41% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 807 publications or more.

View publications distribution as a table
Number of Immunology scientists by publication count, Research.com 2026 ranking edition. Based on 4,929 ranked scientists.
Publications Scientists This scientist
62–71 9
72–81 23
82–91 40
92–101 72
102–111 86
112–121 108
122–131 150
132–141 160
142–151 159
152–161 189
162–171 166
172–181 181
182–191 188
192–201 187
202–211 178
212–221 158 219
222–231 168
232–241 159
242–251 160
252–261 148
262–271 116
272–281 125
282–291 115
292–301 111
302–311 95
312–321 97
322–331 97
332–341 99
342–351 96
352–361 69
362–371 76
372–381 71
382–391 71
392–401 62
402–411 54
412–421 41
422–431 63
432–441 53
442–451 31
452–461 42
462–471 40
472–481 29
482–491 34
492–501 30
502–511 23
512–521 41
522–531 29
532–541 28
542–551 16
552–561 18
562–571 18
572–581 17
582–591 17
592–601 17
602–611 19
612–621 13
622–631 12
632–641 11
642–651 16
652–661 9
662–671 5
672–681 13
682–691 12
692–701 6
702–711 6
712–721 9
722–731 9
732–741 6
742–751 11
752–761 10
762–771 7
772–781 12
782–791 7
792–801 5
802–806 1
807+ 100
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Hiroko Tsutsui D-index placement in Immunology in 2026

The chart shows the D-index (discipline H-index) distribution of Immunology scientists ranked by Research.com in 2026. The highlighted bar marks where Hiroko Tsutsui sits on this spectrum.

No. of scientists
50 100 150 200
Bar chart with 60 bars. Horizontal axis: D-Index, 40–41 to 157+. Vertical axis: number of scientists, 0 to 201. Most scientists, 201, have 58–59 D-Index. The last bar groups every scientist with 157 D-Index or more. The highlighted bar, 68–69 D-Index, is where this scientist sits. 40–41 D-Index: 28 scientists 42–43 D-Index: 91 scientists 44–45 D-Index: 157 scientists 46–47 D-Index: 192 scientists 48–49 D-Index: 175 scientists 50–51 D-Index: 188 scientists 52–53 D-Index: 177 scientists 54–55 D-Index: 155 scientists 56–57 D-Index: 194 scientists 58–59 D-Index: 201 scientists 60–61 D-Index: 197 scientists 62–63 D-Index: 201 scientists 64–65 D-Index: 173 scientists 66–67 D-Index: 167 scientists 68–69 D-Index: 172 scientists 70–71 D-Index: 199 scientists 72–73 D-Index: 184 scientists 74–75 D-Index: 133 scientists 76–77 D-Index: 163 scientists 78–79 D-Index: 127 scientists 80–81 D-Index: 121 scientists 82–83 D-Index: 125 scientists 84–85 D-Index: 121 scientists 86–87 D-Index: 102 scientists 88–89 D-Index: 96 scientists 90–91 D-Index: 75 scientists 92–93 D-Index: 72 scientists 94–95 D-Index: 74 scientists 96–97 D-Index: 66 scientists 98–99 D-Index: 68 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 60 scientists 104–105 D-Index: 54 scientists 106–107 D-Index: 36 scientists 108–109 D-Index: 23 scientists 110–111 D-Index: 52 scientists 112–113 D-Index: 41 scientists 114–115 D-Index: 34 scientists 116–117 D-Index: 25 scientists 118–119 D-Index: 28 scientists 120–121 D-Index: 11 scientists 122–123 D-Index: 20 scientists 124–125 D-Index: 27 scientists 126–127 D-Index: 19 scientists 128–129 D-Index: 20 scientists 130–131 D-Index: 16 scientists 132–133 D-Index: 17 scientists 134–135 D-Index: 14 scientists 136–137 D-Index: 15 scientists 138–139 D-Index: 9 scientists 140–141 D-Index: 11 scientists 142–143 D-Index: 9 scientists 144–145 D-Index: 9 scientists 146–147 D-Index: 7 scientists 148–149 D-Index: 7 scientists 150–151 D-Index: 7 scientists 152–153 D-Index: 5 scientists 154–155 D-Index: 8 scientists 156 D-Index: 6 scientists 157+ D-Index: 96 scientists
40–41 D-Index 157+

This scientist: 69 D-Index — 50th percentile

50% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 157 D-Index or more.

View D-Index distribution as a table
Number of Immunology scientists by D-index, Research.com 2026 ranking edition. Based on 4,929 ranked scientists.
D-Index Scientists This scientist
40–41 28
42–43 91
44–45 157
46–47 192
48–49 175
50–51 188
52–53 177
54–55 155
56–57 194
58–59 201
60–61 197
62–63 201
64–65 173
66–67 167
68–69 172 69
70–71 199
72–73 184
74–75 133
76–77 163
78–79 127
80–81 121
82–83 125
84–85 121
86–87 102
88–89 96
90–91 75
92–93 72
94–95 74
96–97 66
98–99 68
100–101 49
102–103 60
104–105 54
106–107 36
108–109 23
110–111 52
112–113 41
114–115 34
116–117 25
118–119 28
120–121 11
122–123 20
124–125 27
126–127 19
128–129 20
130–131 16
132–133 17
134–135 14
136–137 15
138–139 9
140–141 11
142–143 9
144–145 9
146–147 7
148–149 7
150–151 7
152–153 5
154–155 8
156 6
157+ 96
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Overview

Hiroko Tsutsui is affiliated with Hyogo College of Medicine in Japan and has contributed to research primarily within the field of Medicine. Their work is specialized in several subfields including Oncology, Surgery, Immunology, Epidemiology, and Genetics. The scientist's research topics prominently feature cancer immunotherapy and biomarkers, intestinal and peritoneal adhesions, immunotherapy and immune responses, immune cell function and interaction, coagulation mechanisms including bradykinin and polyphosphates, blood coagulation and thrombosis mechanisms, and the relationship between tryptophan and brain disorders.

Tsutsui has published extensively, with a notable focus on understanding immune responses in cancer and postoperative conditions. Their recent papers include:

  • Antithrombin Together with NETs Inhibitor Protected Against Postoperative Adhesion Formation in Mice (2021, Cellular Physiology and Biochemistry)
  • Caffeine Protects Against Stress-Induced Murine Depression Through Activation of PPARγC1α-Mediated Restoration of the Kynurenine Pathway in the Skeletal Muscle (2021, Scientific Reports)
  • Blockade of Tumor Necrosis Factor by Etanercept Prevents Postoperative Adhesion Formation in Mice (2020, Cellular Physiology and Biochemistry)
  • Carbon Ion Irradiation Activates Anti-Cancer Immunity (2024, International Journal of Molecular Sciences)
  • Autophagy Inhibition Increased Sensitivity of Pancreatic Cancer Cells to Carbon Ion Radiotherapy (2023, Cellular Physiology and Biochemistry)

Publications have been frequently featured in venues such as Cellular Physiology and Biochemistry, International Journal of Molecular Sciences, Scientific Reports, Cureus, and the Journal of Hepato-Biliary-Pancreatic Sciences.

Collaborative research is a significant aspect of Tsutsui's work. Frequent coauthors include:

  • Jiro Fujimoto
  • Keiko Mitani
  • Makoto Sudo
  • Etsuro Hatano
  • Shuhei Hayashi

The combination of fields and topics indicate a cross-disciplinary approach to investigating both basic and translational aspects of medical science, with an emphasis on cancer biology and surgical immunology. The continuous publishing pattern suggests ongoing active engagement in research that bridges laboratory findings and potential clinical applications.

Best Publications

  • Cloning of a new cytokine that induces IFN-gamma production by T cells.

    H Okamura;H Tsutsi;T Komatsu;M Yutsudo

  • Targeted Disruption of the MyD88 Gene Results in Loss of IL-1- and IL-18-Mediated Function

    Osamu Adachi;Taro Kawai;Kiyoshi Takeda;Makoto Matsumoto

  • Interleukin-18 regulates both Th1 and Th2 responses.

    Kenji Nakanishi;Tomohiro Yoshimoto;Hiroko Tsutsui;Haruki Okamura

  • Activation of Interferon-γ Inducing Factor Mediated by Interleukin-1β Converting Enzyme

    Yong Gu;Keisuke Kuida;Hiroko Tsutsui;George Ku

  • Defective NK Cell Activity and Th1 Response in IL-18–Deficient Mice

    Kiyoshi Takeda;Hiroko Tsutsui;Tomohiro Yoshimoto;Osamu Adachi

  • Interleukin-18 is a unique cytokine that stimulates both Th1 and Th2 responses depending on its cytokine milieu.

    Kenji Nakanishi;Tomohiro Yoshimoto;Hiroko Tsutsui;Haruki Okamura

  • Hepatocyte growth factor gene therapy of liver cirrhosis in rats.

    Takahiro Ueki;Yasufumi Kaneda;Hiroko Tsutsui;Kenji Nakanishi

  • SOCS-1 participates in negative regulation of LPS responses.

    Reiko Nakagawa;Tetsuji Naka;Hiroko Tsutsui;Minoru Fujimoto

  • Regulation of interferon-gamma production by IL-12 and IL-18

    Haruki Okamura;Shin-ichiro Kashiwamura;Hiroko Tsutsui;Tomohiro Yoshimoto

  • INTERLEUKIN-18: A NOVEL CYTOKINE THAT AUGMENTS BOTH INNATE AND ACQUIRED IMMUNITY

    Haruki Okamura;Hiroko Tsutsui;Shin-Ichiro Kashiwamura;Tomohiro Yoshimoto

  • IL-18, although antiallergic when administered with IL-12, stimulates IL-4 and histamine release by basophils

    Tomohiro Yoshimoto;Hiroko Tsutsui;Kouji Tominaga;Katsuaki Hoshino

  • IFN-gamma-inducing factor up-regulates Fas ligand-mediated cytotoxic activity of murine natural killer cell clones.

    H Tsutsui;K Nakanishi;K Matsui;K Higashino

  • Interleukin-18 in Health and Disease

    Koubun Yasuda;Kenji Nakanishi;Hiroko Tsutsui

  • IL-18 induction of IgE: dependence on CD4+ T cells, IL-4 and STAT6.

    Tomohiro Yoshimoto;Hitoshi Mizutani;Hiroko Tsutsui;Nancy Noben-Trauth

  • Expression and function of TNF-related apoptosis-inducing ligand on murine activated NK cells.

    Nobuhiko Kayagaki;Noriko Yamaguchi;Masafumi Nakayama;Kazuyoshi Takeda

  • Cutting Edge: Generation of IL-18 Receptor-Deficient Mice: Evidence for IL-1 Receptor-Related Protein as an Essential IL-18 Binding Receptor

    Katsuaki Hoshino;Hiroko Tsutsui;Taro Kawai;Kiyoshi Takeda

  • IL-18 contributes to the spontaneous development of atopic dermatitis-like inflammatory skin lesion independently of IgE/stat6 under specific pathogen-free conditions.

    Hiroshi Konishi;Hiroko Tsutsui;Takaaki Murakami;Shizue Yumikura-Futatsugi

  • Contribution of IL-33–activated type II innate lymphoid cells to pulmonary eosinophilia in intestinal nematode-infected mice

    Koubun Yasuda;Taichiro Muto;Tatsukata Kawagoe;Makoto Matsumoto

  • Caspase-1-independent, Fas/Fas ligand-mediated IL-18 secretion from macrophages causes acute liver injury in mice.

    Hiroko Tsutsui;Nobuhiko Kayagaki;Keisuke Kuida;Hiroki Nakano

  • Critical roles of myeloid differentiation factor 88-dependent proinflammatory cytokine release in early phase clearance of Listeria monocytogenes in mice

    Ekihiro Seki;Hiroko Tsutsui;Noriko M. Tsuji;Nobuki Hayashi

Frequent Co-Authors

Kenji Nakanishi
Kenji Nakanishi Hyogo College of Medicine
Haruki Okamura
Haruki Okamura Hyogo College of Medicine
Shizuo Akira
Shizuo Akira Osaka University
Tomohiro Yoshimoto
Tomohiro Yoshimoto Hyogo College of Medicine
Kiyoshi Takeda
Kiyoshi Takeda Osaka University
Tetsuji Naka
Tetsuji Naka Kōchi University
Osamu Takeuchi
Osamu Takeuchi Kyoto University
Tadamitsu Kishimoto
Tadamitsu Kishimoto Osaka University
Shun'ichiro Taniguchi
Shun'ichiro Taniguchi Shinshu University
Norifumi Kawada
Norifumi Kawada Osaka Metropolitan University

External Links

Personal website of Hiroko Tsutsui

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Best Scientists Citing Hiroko Tsutsui

Shizuo Akira

Shizuo Akira

Osaka University

Publications: 301

Kiyoshi Takeda

Kiyoshi Takeda

Osaka University

Publications: 118

Charles A. Dinarello

Charles A. Dinarello

University of Colorado Anschutz Medical Campus

Publications: 110

Haruki Okamura

Haruki Okamura

Hyogo College of Medicine

Publications: 88

Kenji Kabashima

Kenji Kabashima

Kyoto University

Publications: 66

Richard A. Flavell

Richard A. Flavell

Yale University

Publications: 61

Masashi Kurimoto

Masashi Kurimoto

Okayama University

Publications: 54

Kenji Nakanishi

Kenji Nakanishi

Hyogo College of Medicine

Publications: 52

Mark J. Smyth

Mark J. Smyth

QIMR Berghofer Medical Research Institute

Publications: 51

Hideo Yagita

Hideo Yagita

Juntendo University

Publications: 49

Satoshi Uematsu

Satoshi Uematsu

Osaka Metropolitan University

Publications: 48

Yoichiro Iwakura

Yoichiro Iwakura

Tokyo University of Science

Publications: 46

Osamu Takeuchi

Osamu Takeuchi

Kyoto University

Publications: 44

Katherine A. Fitzgerald

Katherine A. Fitzgerald

University of Massachusetts Chan Medical School

Publications: 44

Masahiro Yamamoto

Masahiro Yamamoto

Osaka University

Publications: 41

Toshikazu Nakamura

Toshikazu Nakamura

Osaka University

Publications: 40

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