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Tetsuji Naka

Tetsuji Naka

D-Index & Metrics

Immunology

D-Index
70
Citations
22030
World Ranking
2386
National Ranking
90

Overview

Tetsuji Naka is affiliated with Kōchi University in Japan. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a significant focus on Oncology, Cancer Research, and Molecular Biology as prominent subfields. Additional subfields include Pulmonary and Respiratory Medicine and Immunology.

The main topics of Tetsuji Naka's work encompass:

  • Cancer, Lipids, and Metabolism
  • Clusterin in disease pathology
  • Cancer, Hypoxia, and Metabolism
  • Angiogenesis and VEGF in Cancer
  • Glycosylation and Glycoproteins Research
  • Ferroptosis and cancer prognosis
  • Cytokine Signaling Pathways and Interactions

Frequent publication venues for Naka include:

  • Cancer Research
  • Gastric Cancer
  • Annals of the Rheumatic Diseases
  • E-Posters
  • Anticancer Research

Notable recent papers authored or co-authored by Naka feature a range of topics in disease biomarkers, cancer therapies, and mechanisms of cancer cell regulation:

  • Leucine-rich alpha-2 glycoprotein is a potential biomarker to monitor disease activity in inflammatory bowel disease receiving adalimumab: PLANET study, 2021, Journal of Gastroenterology
  • GPC1 specific CAR-T cells eradicate established solid tumor without adverse effects and synergize with anti-PD-1 Ab, 2020, eLife
  • SOCS1 Gene Therapy for Head and Neck Cancers: An Experimental Study, 2022, Anticancer Research
  • Anti-glypican-1 antibody-drug conjugate is a potential therapy against pancreatic cancer, 2020, British Journal of Cancer
  • Propranolol suppresses gastric cancer cell growth by regulating proliferation and apoptosis, 2021, Gastric Cancer

Among frequent co-authors are researchers such as Satoshi Serada, Minoru Fujimoto, Kosuke Hiramatsu, Yutaka Ueda, and Tadashi Kimura, indicating collaboration across multiple projects with varying focus areas within oncology and biomedical research.

Best Publications

  • SOCS proteins, cytokine signalling and immune regulation.

    Akihiko Yoshimura;Tetsuji Naka;Masato Kubo

  • Structure and function of a new STAT-induced STAT inhibitor

    Tetsuji Naka;Masashi Narazaki;Moritoshi Hirata;Tomoshige Matsumoto

  • The immune responses in CD40-deficient mice: Impaired immunoglobulin class switching and germinal center formation

    Tsutomu Kawabe;Tetsuji Naka;Kanji Yoshida;Takashi Tanaka

  • SOCS-1 participates in negative regulation of LPS responses.

    Reiko Nakagawa;Tetsuji Naka;Hiroko Tsutsui;Minoru Fujimoto

  • The paradigm of IL-6: from basic science to medicine

    Tetsuji Naka;Norihiro Nishimoto;Tadamitsu Kishimoto

  • Aryl hydrocarbon receptor regulates Stat1 activation and participates in the development of Th17 cells

    Akihiro Kimura;Tetsuji Naka;Keiko Nohara;Yoshiaki Fujii-Kuriyama

  • Aryl hydrocarbon receptor in combination with Stat1 regulates LPS-induced inflammatory responses

    Akihiro Kimura;Tetsuji Naka;Taisuke Nakahama;Ichino Chinen

  • IL-6-dependent and -independent pathways in the development of interleukin 17-producing T helper cells

    Akihiro Kimura;Tetsuji Naka;Tadamitsu Kishimoto

  • IL-6 blockade inhibits the induction of myelin antigen-specific Th17 cells and Th1 cells in experimental autoimmune encephalomyelitis.

    Satoshi Serada;Minoru Fujimoto;Masahiko Mihara;Nobuo Koike

  • Therapeutic strategies in epithelial ovarian cancer

    Ayako Kim;Yutaka Ueda;Tetsuji Naka;Takayuki Enomoto

  • Accelerated apoptosis of lymphocytes by augmented induction of Bax in SSI-1 (STAT-induced STAT inhibitor-1) deficient mice

    Tetsuji Naka;Tomoshige Matsumoto;Masashi Narazaki;Minoru Fujimoto

  • THREE DISTINCT DOMAINS OF SSI-1/SOCS-1/JAB PROTEIN ARE REQUIRED FOR ITS SUPPRESSION OF INTERLEUKIN 6 SIGNALING

    Masashi Narazaki;Minoru Fujimoto;Tomoshige Matsumoto;Yoshiaki Morita

  • Interleukin-6 blockade suppresses autoimmune arthritis in mice by the inhibition of inflammatory Th17 responses.

    Minoru Fujimoto;Satoshi Serada;Masahiko Mihara;Yasushi Uchiyama

  • Regulation of cytokine signaling by SOCS family molecules

    Minoru Fujimoto;Tetsuji Naka

  • Expression of the suppressor of cytokine signaling-5 (SOCS5) negatively regulates IL-4-dependent STAT6 activation and Th2 differentiation

    Yoh Ichi Seki;Katsuhiko Hayashi;Akira Matsumoto;Akira Matsumoto;Noriyasu Seki

  • Signals transducers and activators of transcription (STAT)-induced STAT inhibitor-1 (SSI-1)/suppressor of cytokine signaling-1 (SOCS-1) suppresses tumor necrosis factor α-induced cell death in fibroblasts

    Yoshiaki Morita;Tetsuji Naka;Yoshinori Kawazoe;Minoru Fujimoto

  • Suppressor of cytokine signaling-1 selectively inhibits LPS-induced IL-6 production by regulating JAK-STAT.

    Akihiro Kimura;Tetsuji Naka;Tatsushi Muta;Osamu Takeuchi

  • Serum leucine-rich alpha-2 glycoprotein is a disease activity biomarker in ulcerative colitis

    Satoshi Serada;Minoru Fujimoto;Fumitaka Terabe;Hideki Iijima

  • The absence of IgE antibody-mediated augmentation of immune responses in CD23-deficient mice.

    H Fujiwara;H Kikutani;S Suematsu;T Naka

  • iTRAQ-based proteomic identification of leucine-rich alpha-2 glycoprotein as a novel inflammatory biomarker in autoimmune diseases.

    Satoshi Serada;Minoru Fujimoto;Atsushi Ogata;Fumitaka Terabe

  • Signal transducer and activator of transcription (STAT)-induced STAT inhibitor 1 (SSI-1)/suppressor of cytokine signaling 1 (SOCS1) inhibits insulin signal transduction pathway through modulating insulin receptor substrate 1 (IRS-1) phosphorylation.

    Yoshinori Kawazoe;Tetsuji Naka;Minoru Fujimoto;Hidetsugu Kohzaki

  • CLONING AND FUNCTIONAL ANALYSIS OF NEW MEMBERS OF STAT INDUCED STAT INHIBITOR (SSI) FAMILY : SSI-2 AND SSI-3

    Seijiro Minamoto;Kazuhiro Ikegame;Kiyonobu Ueno;Masashi Narazaki

Frequent Co-Authors

Minoru Fujimoto
Minoru Fujimoto Kōchi University
Tadamitsu Kishimoto
Tadamitsu Kishimoto Osaka University
Tadashi Kimura
Tadashi Kimura Osaka University
Yuichiro Doki
Yuichiro Doki Osaka University
Masaki Mori
Masaki Mori Kyushu University
Manabu Fujimoto
Manabu Fujimoto Osaka University
Eiichi Morii
Eiichi Morii Osaka University
Kenji Nakanishi
Kenji Nakanishi Hyogo College of Medicine
Hiroko Tsutsui
Hiroko Tsutsui Hyogo College of Medicine
Shintaro Nomura
Shintaro Nomura Nomura Holdings (Japan)

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