Minoru Fujimoto

Best Publications

• SOCS-1 participates in negative regulation of LPS responses.

  Reiko Nakagawa;Tetsuji Naka;Hiroko Tsutsui;Minoru Fujimoto

  820
  Citations

• IL-6 blockade inhibits the induction of myelin antigen-specific Th17 cells and Th1 cells in experimental autoimmune encephalomyelitis.

  Satoshi Serada;Minoru Fujimoto;Masahiko Mihara;Nobuo Koike

  475
  Citations

• Accelerated apoptosis of lymphocytes by augmented induction of Bax in SSI-1 (STAT-induced STAT inhibitor-1) deficient mice

  Tetsuji Naka;Tomoshige Matsumoto;Masashi Narazaki;Minoru Fujimoto

  363
  Citations

• THREE DISTINCT DOMAINS OF SSI-1/SOCS-1/JAB PROTEIN ARE REQUIRED FOR ITS SUPPRESSION OF INTERLEUKIN 6 SIGNALING

  Masashi Narazaki;Minoru Fujimoto;Tomoshige Matsumoto;Yoshiaki Morita

  325
  Citations

• Interleukin-6 blockade suppresses autoimmune arthritis in mice by the inhibition of inflammatory Th17 responses.

  Minoru Fujimoto;Satoshi Serada;Masahiko Mihara;Yasushi Uchiyama

  314
  Citations

• Regulation of cytokine signaling by SOCS family molecules

  Minoru Fujimoto;Tetsuji Naka

  309
  Citations

• Signals transducers and activators of transcription (STAT)-induced STAT inhibitor-1 (SSI-1)/suppressor of cytokine signaling-1 (SOCS-1) suppresses tumor necrosis factor α-induced cell death in fibroblasts

  Yoshiaki Morita;Tetsuji Naka;Yoshinori Kawazoe;Minoru Fujimoto

  273
  Citations

• Serum leucine-rich alpha-2 glycoprotein is a disease activity biomarker in ulcerative colitis

  Satoshi Serada;Minoru Fujimoto;Fumitaka Terabe;Hideki Iijima

  233
  Citations

• iTRAQ-based proteomic identification of leucine-rich alpha-2 glycoprotein as a novel inflammatory biomarker in autoimmune diseases.

  Satoshi Serada;Minoru Fujimoto;Atsushi Ogata;Fumitaka Terabe

  229
  Citations

• Signal transducer and activator of transcription (STAT)-induced STAT inhibitor 1 (SSI-1)/suppressor of cytokine signaling 1 (SOCS1) inhibits insulin signal transduction pathway through modulating insulin receptor substrate 1 (IRS-1) phosphorylation.

  Yoshinori Kawazoe;Tetsuji Naka;Minoru Fujimoto;Hidetsugu Kohzaki

  228
  Citations

• Reprint of: Nanoparticles for ex vivo siRNA delivery to dendritic cells for cancer vaccines: Programmed endosomal escape and dissociation.

  Hidetaka Akita;Kentaro Kogure;Rumiko Moriguchi;Yoshio Nakamura

  222
  Citations

• SOCS-1/SSI-1-Deficient NKT Cells Participate in Severe Hepatitis through Dysregulated Cross-Talk Inhibition of IFN-γ and IL-4 Signaling In Vivo

  Tetsuji Naka;Hiroko Tsutsui;Minoru Fujimoto;Yoshinori Kawazoe

  219
  Citations

• The Influence of Excessive IL-6 Production In Vivo on the Development and Function of Foxp3+ Regulatory T Cells

  Minoru Fujimoto;Mayumi Nakano;Fumitaka Terabe;Hirohisa Kawahata

  207
  Citations

• Flavonoids such as luteolin, fisetin and apigenin are inhibitors of interleukin-4 and interleukin-13 production by activated human basophils.

  Toru Hirano;Shinji Higa;Junsuke Arimitsu;Tetsuji Naka

  190
  Citations

• Dysregulation of melanocyte function by Th17‐related cytokines: significance of Th17 cell infiltration in autoimmune vitiligo vulgaris

  Yorihisa Kotobuki;Atsushi Tanemura;Lingli Yang;Saori Itoi

  185
  Citations

• Negative regulation of cytokine signaling: STAT-induced STAT inhibitor.

  Tetsuji Naka;Minoru Fujimoto;Tadamitsu Kishimoto

  183
  Citations

• Blockade of interleukin-6 receptor alleviates disease in mouse model of scleroderma.

  Shun Kitaba;Hiroyuki Murota;Mika Terao;Hiroaki Azukizawa

  168
  Citations

• Proteomics-based identification of α-enolase as a tumor antigen in non-small lung cancer

  Ping He;Tetsuji Naka;Satoshi Serada;Minoru Fujimoto

  160
  Citations

• Blockade of interleukin-6 signaling suppresses experimental autoimmune uveoretinitis by the inhibition of inflammatory Th17 responses

  Satoshi Hohki;Nobuyuki Ohguro;Hiroshi Haruta;Kei Nakai

  146
  Citations

• SOCS1, a Negative Regulator of Cytokine Signals and TLR Responses,in Human Liver Diseases

  Minoru Fujimoto;Tetsuji Naka

  146
  Citations

• Negative regulation of cytokine and TLR signalings by SOCS and others.

  Tetsuji Naka;Minoru Fujimoto;Hiroko Tsutsui;Akihiko Yoshimura

  142
  Citations