World's Best Scientists 2026 revealed!
Robert Rottapel

Robert Rottapel

D-Index & Metrics

Biology and Biochemistry

D-Index
66
Citations
13338
World Ranking
8813
National Ranking
305

Robert Rottapel publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Robert Rottapel sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 169 publications — 36th percentile

36% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Robert Rottapel D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Robert Rottapel sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 66 D-Index — 57th percentile

57% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Robert Rottapel is affiliated with the University of Toronto in Canada and has contributed extensively to research in biochemistry, genetics, molecular biology, and medicine. Their work emphasizes areas such as molecular biology, oncology, immunology, cell biology, and genetics, reflecting a multidisciplinary approach to biomedical science.

The scientist has focused on various research topics, including:

  • PARP inhibition in cancer therapy
  • Hippo pathway signaling and YAP/TAZ
  • Cancer Immunotherapy and Biomarkers
  • COVID-19 Clinical Research Studies
  • Ubiquitin and proteasome pathways
  • Axon Guidance and Neuronal Signaling
  • Cancer-related gene regulation

Rottapel's publication record includes numerous papers in prominent journals. Some recent notable publications are:

  • "N6-Methyladenosine Reader YTHDF1 Promotes ARHGEF2 Translation and RhoA Signaling in Colorectal Cancer," 2021, Gastroenterology
  • "Gain-of-function variants in SYK cause immune dysregulation and systemic inflammation in humans and mice," 2021, Nature Genetics
  • "Preexisting autoimmune disease and immune-related adverse events associated with anti-PD-1 cancer immunotherapy: a national case series from the Canadian Research Group of Rheumatology in Immuno-Oncology," 2021, Cancer Immunology Immunotherapy
  • "Rheumatic immune-related adverse events associated with cancer immunotherapy: A nationwide multi-center cohort," 2020, Autoimmunity Reviews
  • "Advances in ovarian cancer, from biology to treatment," 2021, Nature Cancer

The scientist has published frequently in several key venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Scientific Reports
  • Gastroenterology
  • Nature Genetics
  • Journal of Clinical Investigation

Collaborations appear across multiple coauthors with whom Rottapel has published extensively. Frequent coauthors include:

  • Yoshinori Matsumoto
  • José La Rose
  • Yosuke Asano
  • Jun Wada
  • Amit M. Oza

These collaborations and publication venues reflect a broad network and engagement with various institutions and research groups focused on understanding molecular mechanisms underlying cancer, immune regulation, and cellular signaling pathways.

Best Publications

  • Regulation of NF-κB Signaling by Pin1-Dependent Prolyl Isomerization and Ubiquitin-Mediated Proteolysis of p65/RelA

    Akihide Ryo;Futoshi Suizu;Yasuhiro Yoshida;Kilian Perrem

  • Binding of phosphatidyl-inositol-3-OH kinase to CD28 is required for T-cell signalling

    Françoise Pagès;Marguerite Ragueneau;Robert Rottapel;Robert Rottapel;Alemseged Truneh

  • The MAGUK family protein CARD11 is essential for lymphocyte activation.

    Hiromitsu Hara;Teiji Wada;Teiji Wada;Chris Bakal;Ivona Kozieradzki;Ivona Kozieradzki

  • Measuring error rates in genomic perturbation screens: gold standards for human functional genomics

    Traver Hart;Kevin R Brown;Fabrice Sircoulomb;Robert Rottapel;Robert Rottapel;Robert Rottapel

  • W mutant mice with mild or severe developmental defects contain distinct point mutations in the kinase domain of the c-kit receptor

    A D Reith;R Rottapel;E Giddens;C Brady

  • Essential Gene Profiles in Breast, Pancreatic, and Ovarian Cancer Cells

    Richard Marcotte;Kevin R. Brown;Fernando Suarez;Azin Sayad

  • The c-kit receptor ligand functions as a mast cell chemoattractant.

    Cynthia J. Meininger;Hiroshi Yano;Robert Rottapel;Alan Bernstein

  • The Steel/W transduction pathway: kit autophosphorylation and its association with a unique subset of cytoplasmic signaling proteins is induced by the Steel factor.

    R Rottapel;M Reedijk;D E Williams;S D Lyman

  • A point mutation in CD28 distinguishes proliferative signals from survival signals.

    Klaus Okkenhaug;Klaus Okkenhaug;Linda Wu;Kristine M. Garza;Jose La Rose

  • SHP-1 binds and negatively modulates the c-Kit receptor by interaction with tyrosine 569 in the c-Kit juxtamembrane domain.

    Maya Kozlowski;Louise Larose;Fai Lee;Duc Mingh Le

  • Structural Basis and Sequence Rules for Substrate Recognition by Tankyrase Explain the Basis for Cherubism Disease

    Sebastian Guettler;Sebastian Guettler;Jose LaRose;Evangelia Petsalaki;Evangelia Petsalaki;Gerald Gish

  • Socs1 binds to multiple signalling proteins and suppresses Steel factor-dependent proliferation

    Paulo De Sepulveda;Klaus Okkenhaug;Klaus Okkenhaug;Jose La Rose;Robert G. Hawley

  • Suppressor of cytokine signaling-1 inhibits VAV function through protein degradation.

    Paulo De Sepulveda;Subburaj Ilangumaran;Robert Rottapel;Robert Rottapel

  • The FLT4 gene encodes a transmembrane tyrosine kinase related to the vascular endothelial growth factor receptor.

    Galland F;Karamysheva A;Pebusque Mj;Borg Jp

  • Putting out the fire: coordinated suppression of the innate and adaptive immune systems by SOCS1 and SOCS3 proteins

    Ioannis D. Dimitriou;Liliana Clemenza;Liliana Clemenza;Andrew J. Scotter;Grace Chen;Grace Chen

  • Autoinhibition of the Kit Receptor Tyrosine Kinase by the Cytosolic Juxtamembrane Region

    Perry M. Chan;Subburaj Ilangumaran;Jose La Rose;Avijit Chakrabartty

  • Loss of Tankyrase-Mediated Destruction of 3BP2 Is the Underlying Pathogenic Mechanism of Cherubism

    Noam Levaot;Oleksandr Voytyuk;Ioannis Dimitriou;Fabrice Sircoulomb

  • CD28-dependent Activation of Protein Kinase B/Akt Blocks Fas-mediated Apoptosis by Preventing Death-inducing Signaling Complex Assembly

    Russell G. Jones;Alisha R. Elford;Michael J. Parsons;Linda Wu

  • The antihelmintic flubendazole inhibits microtubule function through a mechanism distinct from Vinca alkaloids and displays preclinical activity in leukemia and myeloma.

    Paul A. Spagnuolo;Jiayi Hu;Rose Hurren;Xiaoming Wang

  • Constitutive p38HOG Mitogen-activated Protein Kinase Activation Induces Permanent Cell Cycle Arrest and Senescence

    Rizwan Haq;James D Brenton;Mark Takahashi;Dina Finan

Frequent Co-Authors

Mitsuhiko Ikura
Mitsuhiko Ikura Princess Margaret Cancer Centre
Klaus Okkenhaug
Klaus Okkenhaug University of Cambridge
Anne-Claude Gingras
Anne-Claude Gingras Lunenfeld-Tanenbaum Research Institute
Benjamin G. Neel
Benjamin G. Neel New York University Langone Medical Center
Pamela S. Ohashi
Pamela S. Ohashi Princess Margaret Cancer Centre
Christopher J. Paige
Christopher J. Paige Princess Margaret Cancer Centre
Jason Moffat
Jason Moffat University of Toronto
Josef M. Penninger
Josef M. Penninger University of British Columbia

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