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Molecular Biology
USA
2025

D-Index & Metrics

Molecular Biology

D-Index
131
Citations
65370
World Ranking
183
National Ranking
114

Research.com Recognitions

  • 2025 - Research.com Molecular Biology in United States Leader Award
  • 2023 - Research.com Molecular Biology in United States Leader Award

Overview

Benjamin G. Neel is affiliated with the New York University Langone Medical Center in the United States. Their research primarily spans the fields of Biochemistry, Genetics, and Molecular Biology, with significant contributions also in Medicine.

The scientist's work heavily focuses on subfields such as Molecular Biology, Immunology, Oncology, Radiology, Nuclear Medicine and Imaging, and Physiology. Within these areas, key research topics include Protein Tyrosine Phosphatases, Galectins and Cancer Biology, Ubiquitin and proteasome pathways, CAR-T cell therapy research, interferon and immune responses, CRISPR and Genetic Engineering, and Monoclonal and Polyclonal Antibodies Research.

Benjamin G. Neel has authored numerous publications, with notable papers including:

  • The current state of the art and future trends in RAS-targeted cancer therapies, 2022, Nature Reviews Clinical Oncology
  • SHP2 inhibition diminishes KRASG12C cycling and promotes tumor microenvironment remodeling, 2020, The Journal of Experimental Medicine
  • Genetically Defined Syngeneic Mouse Models of Ovarian Cancer as Tools for the Discovery of Combination Immunotherapy, 2020, Cancer Discovery
  • Distinct fibroblast functional states drive clinical outcomes in ovarian cancer and are regulated by TCF21, 2020, The Journal of Experimental Medicine
  • Genome-Wide CRISPR Screens Identify Multiple Synthetic Lethal Targets That Enhance KRASG12C Inhibitor Efficacy, 2023, Cancer Research

Frequent collaborators in their research include Kwok-Kin Wong, Takamitsu Hattori, Shohei Koide, Akiko Koide, and Igor Dolgalev.

Benjamin G. Neel's studies are often published in venues such as bioRxiv (Cold Spring Harbor Laboratory), Cancer Research, Proceedings of the National Academy of Sciences, The Journal of Experimental Medicine, and Cancer Discovery.

Best Publications

  • SH2 domains recognize specific phosphopeptide sequences

    Songyang Zhou;Songyang Zhou;Steven E. Shoelson;Manas Chaudhuri;Gerald Gish

  • New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

    Lewis C. Cantley;Benjamin G. Neel

  • Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis

    William S. Hayward;Benjamin G. Neel;Susan M. Astrin

  • Increased Energy Expenditure, Decreased Adiposity, and Tissue-Specific Insulin Sensitivity in Protein-Tyrosine Phosphatase 1B-Deficient Mice

    Lori D. Klaman;Olivier Boss;Odile D. Peroni;Jason K. Kim

  • The ‘Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling

    Benjamin G. Neel;Haihua Gu;Lily Pao

  • STAT3 signalling is required for leptin regulation of energy balance but not reproduction.

    Sarah H. Bates;Walter H. Stearns;Trevor A. Dundon;Markus Schubert

  • Solubilization and Purification of Enzymatically Active Glutathione S-Transferase (pGEX) Fusion Proteins

    J.V. Frangioni;B.G. Neel

  • SPECIFIC RECRUITMENT OF SH-PTP1 TO THE ERYTHROPOIETIN RECEPTOR CAUSES INACTIVATION OF JAK2 AND TERMINATION OF PROLIFERATIVE SIGNALS

    Ursula Klingmüller;Ursula Klingmüller;Ulrike Lorenz;Lewis C Cantley;Benjamin G Neel

  • PTP1B regulates leptin signal transduction in vivo.

    Janice M. Zabolotny;Kendra K. Bence-Hanulec;Alain Stricker-Krongrad;Fawaz Haj

  • Protein tyrosine phosphatases in signal transduction.

    Benjamin G Neel;Nicholas K Tonks

  • The nontransmembrane tyrosine phosphatase PTP-1B localizes to the endoplasmic reticulum via its 35 amino acid C-terminal sequence

    John V. Frangioni;Pamela H. Beahm;Victor Shifrin;Christine A. Jost

  • From form to function: signaling by protein tyrosine phosphatases.

    Nicholas K Tonks;Benjamin G Neel

  • Neuronal PTP1B regulates body weight, adiposity and leptin action

    Kendra K Bence;Mirela Delibegovic;Bingzhong Xue;Cem Z Gorgun

  • Germline gain-of-function mutations in SOS1 cause Noonan syndrome

    Amy E Roberts;Toshiyuki Araki;Kenneth D Swanson;Kate T Montgomery

  • Mathematical models of protein kinase signal transduction.

    Reinhart Heinrich;Benjamin G. Neel;Tom A. Rapoport

  • Combinatorial control of the specificity of protein tyrosine phosphatases.

    Nicholas K Tonks;Benjamin G Neel

  • Avian leukosis virus-induced tumors have common proviral integration sites and synthesize discrete new RNAs: oncogenesis by promoter insertion

    Benjamin G. Neel;William S. Hayward;Harriet L. Robinson;Joanna Fang

  • Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression

    Luisa Cimmino;Igor Dolgalev;Yubao Wang;Akihide Yoshimi

  • An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity

    Oded Kopper;Chris J de Witte;Kadi Lõhmussaar;Jose Espejo Valle-Inclan

  • Activating Mutations of the Noonan Syndrome-Associated SHP2/PTPN11 Gene in Human Solid Tumors and Adult Acute Myelogenous Leukemia

    Mohamed Bentires-Alj;J. Guillermo Paez;Frank S. David;Heike Keilhack

Frequent Co-Authors

Barbara B. Kahn
Barbara B. Kahn Beth Israel Deaconess Medical Center
Zhong Yin Zhang
Zhong Yin Zhang Purdue University West Lafayette
Mitsuhiko Ikura
Mitsuhiko Ikura Princess Margaret Cancer Centre
Jeffery L. Kutok
Jeffery L. Kutok Epizyme (United States)
Nicholas K. Tonks
Nicholas K. Tonks Cold Spring Harbor Laboratory
Tony Tiganis
Tony Tiganis Peter MacCallum Cancer Centre
John Douglas Mcpherson
John Douglas Mcpherson University of California, Davis
Jason Moffat
Jason Moffat University of Toronto
Lincoln Stein
Lincoln Stein Ontario Institute for Cancer Research
Jason K. Kim
Jason K. Kim University of Massachusetts Chan Medical School

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