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Takashi Matozaki

Takashi Matozaki

D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
18204
World Ranking
10605
National Ranking
720

Overview

Takashi Matozaki is affiliated with Kobe University in Japan. Their research spans multiple fields including Immunology and Microbiology, Medicine, and Biochemistry, Genetics and Molecular Biology. Within these areas, Matozaki has contributed notably to subfields such as Immunology, Molecular Biology, Oncology, Physiology, and Surgery.

The scientist's work addresses several main topics of study, including:

  • Phagocytosis and Immune Regulation
  • Immunotherapy and Immune Responses
  • Immune cells in cancer
  • Cancer Cells and Metastasis
  • PI3K/AKT/mTOR signaling in cancer
  • Immune Cell Function and Interaction
  • Cancer Immunotherapy and Biomarkers

Among Matozaki's recent papers are:

  • "The Role of Type-2 Conventional Dendritic Cells in the Regulation of Tumor Immunity" (2022), published in Cancers
  • "THBS1-producing tumor-infiltrating monocyte-like cells contribute to immunosuppression and metastasis in colorectal cancer" (2023), published in Nature Communications
  • "Relayed signaling between mesenchymal progenitors and muscle stem cells ensures adaptive stem cell response to increased mechanical load" (2021), published in Cell Stem Cell
  • "Macrocyclic Peptide-Mediated Blockade of the CD47-SIRPα Interaction as a Potential Cancer Immunotherapy" (2020), published in Cell Chemical Biology
  • "Lysosomal cholesterol overload in macrophages promotes liver fibrosis in a mouse model of NASH" (2023), published in The Journal of Experimental Medicine

Matozaki frequently collaborates with several co-authors, including:

  • Yasuyuki Saito
  • Takenori Kotani
  • Yoji Murata
  • Satomi Komori
  • Daisuke Hazama

The most common venues for Matozaki's publications include:

  • Proceedings of the National Academy of Sciences
  • Cancer Science
  • Frontiers in Immunology
  • Journal of Gastroenterology
  • Cancer Research

Best Publications

  • Small GTP-Binding Proteins

    Yoshimi Takai;Takuya Sasaki;Takashi Matozaki

  • Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasis

    Takako Koga;Masanori Inui;Kazuya Inoue;Sunhwa Kim

  • Small GTP-binding proteins.

    Yoshimi Takai;Kozo Kaibuchi;Akira Kikuchi;Masahito Kawata

  • A novel membrane glycoprotein, SHPS-1, that binds the SH2-domain-containing protein tyrosine phosphatase SHP-2 in response to mitogens and cell adhesion.

    Y Fujioka;T Matozaki;T Noguchi;A Iwamatsu

  • Functions and molecular mechanisms of the CD47–SIRPα signalling pathway

    Takashi Matozaki;Yoji Murata;Hideki Okazawa;Hiroshi Ohnishi

  • Role of SH-PTP2, a protein-tyrosine phosphatase with Src homology 2 domains, in insulin-stimulated Ras activation.

    T Noguchi;T Matozaki;K Horita;Y Fujioka

  • Neutrophils Kill Antibody-Opsonized Cancer Cells by Trogoptosis.

    Hanke L Matlung;Liane Babes;Xi Wen Zhao;Michel van Houdt

  • CD47–signal regulatory protein-α (SIRPα) interactions form a barrier for antibody-mediated tumor cell destruction

    Xi Wen Zhao;Ellen M. van Beek;Karin Schornagel;Hans Van der Maaden

  • Negative Regulation of Phagocytosis in Macrophages by the CD47-SHPS-1 System

    Hideki Okazawa;Sei-ichiro Motegi;Naoko Ohyama;Hiroshi Ohnishi

  • Protein tyrosine phosphatase SHP-2: a proto-oncogene product that promotes Ras activation.

    Takashi Matozaki;Yoji Murata;Yasuyuki Saito;Hideki Okazawa

  • Coendocytosis of cadherin and c-Met coupled to disruption of cell-cell adhesion in MDCK cells--regulation by Rho, Rac and Rab small G proteins.

    Takashi Kamei;Takashi Matozaki;Toshiaki Sakisaka;Atsuko Kodama

  • Promotion of Intestinal Epithelial Cell Turnover by Commensal Bacteria: Role of Short-Chain Fatty Acids

    Jung Ha Park;Takenori Kotani;Tasuku Konno;Jajar Setiawan

  • Two functionally distinct cholecystokinin receptors show different modes of action on Ca2+ mobilization and phospholipid hydrolysis in isolated rat pancreatic acini. Studies using a new cholecystokinin analog, JMV-180.

    Takashi Matozaki;Burkhard Göke;Yasuhiro Tsunoda;Marc Rodriguez

  • SHPS-1 regulates integrin-mediated cytoskeletal reorganization and cell motility

    Kenjiro Inagaki;Takuji Yamao;Tetsuya Noguchi;Takashi Matozaki

  • Integrin-mediated Tyrosine Phosphorylation of SHPS-1 and Its Association with SHP-2 ROLES OF Fak AND Src FAMILY KINASES

    Masahiro Tsuda;Takashi Matozaki;Kaoru Fukunaga;Yohsuke Fujioka

  • PI 3-kinase gamma and protein kinase C-zeta mediate RAS-independent activation of MAP kinase by a Gi protein-coupled receptor.

    Hitoshi Takeda;Takashi Matozaki;Toshiyuki Takada;Tetsuya Noguchi

  • Small G-protein networks: their crosstalk and signal cascades.

    Takashi Matozaki;Hiroyuki Nakanishi;Yoshimi Takai

  • Involvement of an SHP-2-Rho Small G Protein Pathway in Hepatocyte Growth Factor/Scatter Factor–induced Cell Scattering

    Atsuko Kodama;Takashi Matozaki;Atsunori Fukuhara;Mitsuhiro Kikyo

  • The CD47–SIRPα signalling system: its physiological roles and therapeutic application

    Yoji Murata;Takenori Kotani;Hiroshi Ohnishi;Takashi Matozaki

  • Negative regulation of platelet clearance and of the macrophage phagocytic response by the transmembrane glycoprotein SHPS-1.

    Takuji Yamao;Tetsuya Noguchi;Osamu Takeuchi;Uichi Nishiyama

Frequent Co-Authors

Masato Kasuga
Masato Kasuga National Center For Global Health and Medicine
Timo K. van den Berg
Timo K. van den Berg Radboud University
Yoshimi Takai
Yoshimi Takai Kobe University
Osamu Ishikawa
Osamu Ishikawa Gunma University
Taco W. Kuijpers
Taco W. Kuijpers University of Amsterdam
Georg Kraal
Georg Kraal Vrije Universiteit Amsterdam
Masamitsu Ichihashi
Masamitsu Ichihashi Kobe University
Masayuki Miyasaka
Masayuki Miyasaka Osaka University
John A. Williams
John A. Williams University of Michigan–Ann Arbor
Keizo Takao
Keizo Takao University of Toyama

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