World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
98
Citations
41002
World Ranking
1640
National Ranking
918

Research.com Recognitions

  • 2014 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

David D. Roberts is affiliated with the National Institutes of Health in the United States. Their research spans fields including Biochemistry, Genetics and Molecular Biology, Immunology and Microbiology, and Medicine. The primary subfields they contribute to are Immunology, Molecular Biology, Physiology, Surgery, and Cell Biology.

Roberts' work concentrates on topics such as Phagocytosis and Immune Regulation, Extracellular vesicles in disease, Pancreatic function and diabetes, Angiogenesis and VEGF in Cancer, Erythrocyte Function and Pathophysiology, Immunotherapy and Immune Responses, and Immune cells in cancer.

Their recent publications include:

  • "Functions of Thrombospondin-1 in the Tumor Microenvironment" (2021) published in the International Journal of Molecular Sciences
  • "Preclinical and clinical development of therapeutic antibodies targeting functions of CD47 in the tumor microenvironment" (2020) published in Antibody Therapeutics
  • "THBS1 (thrombospondin-1)" (2020) published in Atlas of Genetics and Cytogenetics in Oncology and Haematology
  • "Emerging functions of thrombospondin-1 in immunity" (2023) published in Seminars in Cell and Developmental Biology
  • "Thrombospondin-1 in maladaptive aging responses: a concept whose time has come" (2020) published in American Journal of Physiology-Cell Physiology

Frequent coauthors of Roberts include:

  • Sukhbir Kaur
  • Thomas J. Meyer
  • Satya P. Singh
  • Jennifer D. Petersen
  • Joshua Zimmerberg

Roberts has published frequently in the following venues:

  • International Journal of Molecular Sciences
  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • Journal of Cell Communication and Signaling
  • American Journal of Physiology-Cell Physiology
  • eLife

In addition to journal articles, Roberts has contributed to book publications, including one book titled Fascist Interactions released by Berghahn Books in 2022.

David D. Roberts was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2014.

Best Publications

  • Minimal information for studies of extracellular vesicles 2018 (MISEV2018) : a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

    Clotilde Théry;Kenneth W. Witwer;Elena Aikawa;Maria Jose Alcaraz

  • The chemical biology of nitric oxide: implications in cellular signaling.

    Douglas D. Thomas;Lisa A. Ridnour;Jeffrey S. Isenberg;Wilmarie Flores-Santana

  • Improved DNA: liposome complexes for increased systemic delivery and gene expression.

    Nancy Smyth Templeton;Danilo D. Lasic;Peter M. Frederik;Helmut H. Strey

  • A self-tuning DVS processor using delay-error detection and correction

    S. Das;D. Roberts;Seokwoo Lee;S. Pant

  • Regulation of Transforming Growth Factor-β Activation by Discrete Sequences of Thrombospondin 1

    Stacey Schultz-Cherry;Hui Chen;Deane F. Mosher;Tina M. Misenheimer

  • Platelet thrombospondin modulates endothelial cell adhesion, motility, and growth: a potential angiogenesis regulatory factor.

    Giulia Taraboletti;David Roberts;Lance A. Liotta;Raffaella Giavazzi

  • Many pulmonary pathogenic bacteria bind specifically to the carbohydrate sequence GalNAc beta 1-4Gal found in some glycolipids.

    Howard C. Krivan;David D. Roberts;Victor Ginsburg

  • Transfection of Thrombospondin 1 Complementary DNA into a Human Breast Carcinoma Cell Line Reduces Primary Tumor Growth, Metastatic Potential, and Angiogenesis

    Debra L. Weinstat-Saslow;Vivian S. Zabrenetzky;Kenneth VanHoutte;William A. Frazier

  • Thrombospondin binds falciparum malaria parasitized erythrocytes and may mediate cytoadherence.

    David D. Roberts;James A. Sherwood;Steven L. Spitalnik;Lindsey J. Panton

  • Inhibition of Angiogenesis by Thrombospondin-1 Is Mediated by 2 Independent Regions Within the Type 1 Repeats

    M. Luisa Iruela-Arispe;Michele Lombardo;Henry C. Krutzsch;Jack Lawler

  • Thrombospondin 1 and Type I Repeat Peptides of Thrombospondin 1 Specifically Induce Apoptosis of Endothelial Cells.

    Neng-hua Guo;Henry C. Krutzsch;John K. Inman;David D. Roberts

  • Nitric oxide regulates angiogenesis through a functional switch involving thrombospondin-1

    Lisa A. Ridnour;Jeffrey S. Isenberg;Michael G. Espey;Douglas D. Thomas

  • Improving NAND Flash Based Disk Caches

    Taeho Kgil;David Roberts;Trevor Mudge

  • Regulation of tumor growth and metastasis by thrombospondin-1.

    David D. Roberts

  • Regulation of nitric oxide signalling by thrombospondin 1: implications for anti-angiogenic therapies

    Jeff S. Isenberg;Gema Martin-Manso;Justin B. Maxhimer;David D. Roberts

  • CD47 Is Necessary for Inhibition of Nitric Oxide-stimulated Vascular Cell Responses by Thrombospondin-1

    Jeff S. Isenberg;Lisa A. Ridnour;Julie Dimitry;William A. Frazier

  • Thrombospondin-1 inhibits endothelial cell responses to nitric oxide in a cGMP-dependent manner

    Jeff S. Isenberg;Lisa A. Ridnour;Elizabeth M. Perruccio;Michael G. Espey

  • Expression of the extracellular matrix molecule thrombospondin inversely correlates with malignant progression in melanoma, lung and breast carcinoma cell lines.

    Vivian Zabrenetzky;Curtis C. Harris;Patricia S. Steeg;David D. Roberts

  • Reactivity of small thiolate anions and cysteine-25 in papain toward methyl methanethiosulfonate.

    David D. Roberts;Sidney D. Lewis;David P. Ballou;Steven T. Olson

  • Thrombospondin-induced tumor cell migration: haptotaxis and chemotaxis are mediated by different molecular domains.

    Giulia Taraboletti;David D. Roberts;Lance A. Liotta

Frequent Co-Authors

David A. Wink
David A. Wink National Institutes of Health
Henry C. Krutzsch
Henry C. Krutzsch National Institutes of Health
William A. Frazier
William A. Frazier Washington University in St. Louis
Victor Ginsburg
Victor Ginsburg National Institutes of Health
Irwin J. Goldstein
Irwin J. Goldstein University of Michigan–Ann Arbor
Trevor Mudge
Trevor Mudge University of Michigan–Ann Arbor
Maria Tsokos
Maria Tsokos Beth Israel Deaconess Medical Center
Deane F. Mosher
Deane F. Mosher University of Wisconsin–Madison
Mones Abu-Asab
Mones Abu-Asab National Institutes of Health
Lance A. Liotta
Lance A. Liotta George Mason University

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