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Biology and Biochemistry

D-Index
107
Citations
36845
World Ranking
1115
National Ranking
667

Research.com Recognitions

  • 2014 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Deane F. Mosher is a researcher affiliated with the University of Wisconsin-Madison in the United States. Their research activities primarily span across the fields of Medicine and Immunology and Microbiology, with a substantial focus on multiple subfields including Immunology, Immunology and Allergy, Rheumatology, Molecular Biology, and Physiology.

The main topics covered in their work include Cell Adhesion Molecules Research, Eosinophilic Disorders and Syndromes, Asthma and respiratory diseases, IL-33, ST2, and ILC Pathways, COVID-19 Clinical Research Studies, Metabolomics and Mass Spectrometry Studies, and Neutrophil, Myeloperoxidase and Oxidative Mechanisms.

Recent publications by Mosher reveal a focus on multi-omic analyses, immune cell function, and extracellular matrix proteins related to disease mechanisms. Selected recent papers include:

  • Large-Scale Multi-omic Analysis of COVID-19 Severity, 2020, Cell Systems
  • Large-scale Multi-omic Analysis of COVID-19 Severity, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • Myeloid-derived growth factor regulates neutrophil motility in interstitial tissue damage, 2021, The Journal of Cell Biology
  • Cardiac differentiation of human pluripotent stem cells using defined extracellular matrix proteins reveals essential role of fibronectin, 2022, eLife
  • αIIb-Integrin (CD41) associated with blood eosinophils is a potential biomarker for disease activity in eosinophilic esophagitis, 2020, Journal of Allergy and Clinical Immunology

Mosher frequently publishes in venues such as bioRxiv (Cold Spring Harbor Laboratory), UNC Libraries, Microscopy and Microanalysis, Cell Systems, and The Journal of Cell Biology. This reflects a pattern of disseminating work in both preprint repositories and peer-reviewed journals focused on cell biology and immunology.

Collaborations are an important aspect of Mosher's research, with several frequent co-authors contributing to the work. These collaborators include Mats W. Johansson, Joshua M. Mitchell, Laura K. Muehlbauer, Bradford S. Schwartz, and Joshua J. Coon.

In 2014, Mosher was recognized as a Fellow of the American Association for the Advancement of Science (AAAS).

Best Publications

  • Thrombospondins Are Astrocyte-Secreted Proteins that Promote CNS Synaptogenesis

    Karen S. Christopherson;Erik M. Ullian;Caleb C.A. Stokes;Christine E. Mullowney

  • Gabapentin Receptor α2δ-1 Is a Neuronal Thrombospondin Receptor Responsible for Excitatory CNS Synaptogenesis

    Çagla Eroglu;Çagla Eroglu;Nicola J. Allen;Michael W. Susman;Nancy A. O'Rourke

  • Cross-linking of cold-insoluble globulin by fibrin-stabilizing factor.

    DF Mosher

  • Synthesis of fibronectin by cultured human endothelial cells.

    E A Jaffe;D F Mosher

  • High molecular weight, cell surface-associated glycoprotein (fibronectin) lost in maglinant transformation

    Anti Vaheri;Anti Vaheri;Deane F. Mosher;Deane F. Mosher

  • Regulation of Transforming Growth Factor-β Activation by Discrete Sequences of Thrombospondin 1

    Stacey Schultz-Cherry;Hui Chen;Deane F. Mosher;Tina M. Misenheimer

  • Large-Scale Multi-omic Analysis of COVID-19 Severity.

    Katherine A. Overmyer;Evgenia Shishkova;Ian J. Miller;Joseph Balnis

  • Syndecan-4 signals cooperatively with integrins in a Rho-dependent manner in the assembly of focal adhesions and actin stress fibers.

    Stefania Saoncella;Frank Echtermeyer;Fabienne Denhez;Julie K. Nowlen

  • Polymerization of Type I and III Collagens Is Dependent On Fibronectin and Enhanced By Integrins α11β1and α2β1

    Teet Velling;Juha Risteli;Krister Wennerberg;Deane F. Mosher

  • PHYSIOLOGY OF FIBRONECTIN

    Deane F. Mosher

  • Cross-linking of fibronectin to collagen by blood coagulation Factor XIIIa.

    D F Mosher;P E Schad

  • Interaction of the 70,000-mol-wt amino-terminal fragment of fibronectin with the matrix-assembly receptor of fibroblasts.

    P J McKeown-Longo;D F Mosher

  • Fibronectin: structure, assembly, and cardiovascular implications.

    Magnus K. Magnusson;Deane F. Mosher

  • Synthesis and secretion of thrombospondin by cultured human endothelial cells.

    D F Mosher;M J Doyle;E A Jaffe

  • Binding of plasma fibronectin to cell layers of human skin fibroblasts.

    P J McKeown-Longo;D F Mosher

  • Cultured human fibroblasts synthesize and secrete thrombospondin and incorporate it into extracellular matrix

    Eric A. Jaffe;Joseph T. Ruggiero;Lawrence L. K. Leung;Mary Jean Doyle

  • Binding and factor XIIIa-mediated cross-linking of a 27-kilodalton fragment of fibronectin to Staphylococcus aureus

    Deane F. Mosher;Richard A. Proctor

  • Fibronectin Regulates Latent Transforming Growth Factor-β (TGFβ) by Controlling Matrix Assembly of Latent TGFβ-binding Protein-1 *

    Sarah L. Dallas;Pitchumani Sivakumar;Carolyn J.P. Jones;Qian Chen

  • Fibronectin concentration is decreased in plasma of severely ill patients with disseminated intravascular coagulation.

    Mosher Df;Williams Em

  • Gabapentin Receptor alpha 2 delta-1 Is a Neuronal Thrombospondin Receptor Responsible for Excitatory CNS Synaptogenesis

    Cagla Eroglu;Nicola J. Allen;Michael W. Susman;Nancy A. O'Rourke

Frequent Co-Authors

Joanne E. Murphy-Ullrich
Joanne E. Murphy-Ullrich University of Alabama at Birmingham
Stuart L. Cooper
Stuart L. Cooper The Ohio State University
Nizar N. Jarjour
Nizar N. Jarjour University of Wisconsin–Madison
Leo T. Furcht
Leo T. Furcht University of Minnesota
David D. Roberts
David D. Roberts National Institutes of Health
Joshua J. Coon
Joshua J. Coon University of Wisconsin–Madison
William W. Busse
William W. Busse University of Wisconsin–Madison
Richard A. Proctor
Richard A. Proctor University of Wisconsin–Madison
Dieter P. Reinhardt
Dieter P. Reinhardt McGill University
Jack Lawler
Jack Lawler Beth Israel Deaconess Medical Center

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