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D-Index & Metrics

Biology and Biochemistry

D-Index
51
Citations
8303
World Ranking
17274
National Ranking
7105

Overview

Victoria L. Bautch is affiliated with the University of North Carolina at Chapel Hill in the United States. Their research primarily spans the fields of biochemistry, genetics, and molecular biology, with considerable contributions in medicine. The scientist's work is concentrated within key subfields such as molecular biology, cell biology, oncology, ophthalmology, and pulmonary and respiratory medicine.

Their research addresses multiple prevalent topics including angiogenesis and VEGF in cancer, congenital heart defects research, single-cell and spatial transcriptomics, zebrafish biomedical research applications, TGF-β signaling in diseases, renal and related cancers, and nuclear structure and function.

Victoria L. Bautch has an extensive publication record with a strong presence in several scientific venues. Some of the most frequent publication venues are:

  • UNC Libraries
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Angiogenesis
  • PLoS Computational Biology
  • Arteriosclerosis Thrombosis and Vascular Biology

Frequent co-authors collaborating with Bautch include:

  • Ziqing Liu
  • Kaitlyn Quigley
  • Feilim Mac Gabhann
  • Karina Kinghorn
  • Allison Marvin

Representative recent papers authored by Victoria L. Bautch include:

  • "Single-Cell RNA Sequencing Reveals Endothelial Cell Transcriptome Heterogeneity Under Homeostatic Laminar Flow," 2021, published in Arteriosclerosis Thrombosis and Vascular Biology
  • "The versatility and paradox of BMP signaling in endothelial cell behaviors and blood vessel function," 2022, published in Cellular and Molecular Life Sciences
  • "Nuclear SUN1 stabilizes endothelial cell junctions via microtubules to regulate blood vessel formation," 2023, published in eLife
  • "SMAD6 transduces endothelial cell flow responses required for blood vessel homeostasis," 2021, published in Angiogenesis
  • "Excess centrosomes disrupt vascular lumenization and endothelial cell adherens junctions," 2020, published in Angiogenesis

Best Publications

  • Development of neuroendocrine tumors in the gastrointestinal tract of transgenic mice. Heterogeneity of hormone expression.

    Guido Rindi;Seth G N Grant;Yiangos Yiangou;Yiangos Yiangou;Mohammed A. Ghatei

  • A sonic hedgehog signaling domain in the arterial adventitia supports resident Sca1+ smooth muscle progenitor cells

    Jenna N. Passman;Xiu Rong Dong;San Pin Wu;San Pin Wu;Colin T. Maguire

  • Embryonic stem cell-derived cystic embryoid bodies form vascular channels: an in vitro model of blood vessel development

    Rong Wang;Rebecca Clark;Victoria L. Bautch

  • The VEGF receptor flt-1 (VEGFR-1) is a positive modulator of vascular sprout formation and branching morphogenesis

    Joseph B. Kearney;Nicholas C. Kappas;Catharina Ellerstrom;Frank W. DiPaola

  • BMPER, a novel endothelial cell precursor-derived protein, antagonizes bone morphogenetic protein signaling and endothelial cell differentiation

    Martin Moser;Olav Binder;Yaxu Wu;Julius Aitsebaomo

  • Local Guidance of Emerging Vessel Sprouts Requires Soluble Flt-1

    John C. Chappell;Sarah M. Taylor;Napoleone Ferrara;Victoria L. Bautch

  • The vascular endothelial growth factor (VEGF) receptor Flt-1 (VEGFR-1) modulates Flk-1 (VEGFR-2) signaling during blood vessel formation.

    David M. Roberts;Joseph B. Kearney;Jennifer H. Johnson;Michael P. Rosenberg

  • Distinct signalling pathways regulate sprouting angiogenesis from the dorsal aorta and the axial vein

    David M. Wiley;Jun Dae Kim;Jijun Hao;Charles C. Hong;Charles C. Hong

  • A Role for Fractalkine and Its Receptor (CX3CR1) in Cardiac Allograft Rejection

    Lisa A. Robinson;Chandra Nataraj;Dennis W. Thomas;David N. Howell

  • The VEGF receptor Flt-1 spatially modulates Flk-1 signaling and blood vessel branching

    Nicholas C. Kappas;Gefei Zeng;John C. Chappell;Joseph B. Kearney

  • Vascular Endothelial Growth Factor-Toxin Conjugate Specifically Inhibits KDR/flk-1-positive Endothelial Cell Proliferation in Vitro and Angiogenesis in Vivo

    S. Ramakrishnan;T. A. Olson;V. L. Bautch;D. Mohanraj

  • Stem cells and the vasculature

    Victoria L Bautch

  • Vascular endothelial growth factor receptor Flt-1 negatively regulates developmental blood vessel formation by modulating endothelial cell division

    Joseph B. Kearney;Carrie A. Ambler;Kelli Ann Monaco;Natalie Johnson

  • THE NEURAL TUBE PATTERNS VESSELS DEVELOPMENTALLY USING THE VEGF SIGNALING PATHWAY

    Kelly A Hogan;Carrie A Ambler;Deborah L Chapman;Victoria L Bautch

  • Endothelial cell tumors develop in transgenic mice carrying polyoma virus middle T oncogene

    Victoria L. Bautch;Sachiko Toda;John A. Hassell;Douglas Hanahan

  • Orientation of endothelial cell division is regulated by VEGF signaling during blood vessel formation.

    Gefei Zeng;Sarah M. Taylor;Janet R. McColm;Nicholas C. Kappas

  • Assembly of trunk and limb blood vessels involves extensive migration and vasculogenesis of somite-derived angioblasts.

    Carrie A. Ambler;Julie L. Nowicki;Ann C. Burke;Victoria L. Bautch

  • Endocardial cells are a distinct endothelial lineage derived from Flk1+ multipotent cardiovascular progenitors

    Andrew M. Misfeldt;Scott C. Boyle;Kevin L. Tompkins;Victoria L. Bautch

  • Neurovascular development uses VEGF-A signaling to regulate blood vessel ingression into the neural tube

    Jennifer M. James;Cara Gewolb;Victoria L. Bautch

  • Neutralizing VEGF decreases tortuosity and alters endothelial cell division orientation in arterioles and veins in a rat model of ROP: relevance to plus disease.

    M. Elizabeth Hartnett;David Martiniuk;Grace Byfield;Pete Geisen

Frequent Co-Authors

Douglas Hanahan
Douglas Hanahan École Polytechnique Fédérale de Lausanne
Cam Patterson
Cam Patterson University of Arkansas for Medical Sciences
William L. Stanford
William L. Stanford Ottawa Hospital
W. Kimryn Rathmell
W. Kimryn Rathmell Vanderbilt University Medical Center
Dhavalkumar D. Patel
Dhavalkumar D. Patel University of North Carolina at Chapel Hill
Seth G. N. Grant
Seth G. N. Grant University of Edinburgh
Charles C. Hong
Charles C. Hong University of Maryland, Baltimore
James E. Bear
James E. Bear University of North Carolina at Chapel Hill
Michael Leitges
Michael Leitges University of Oslo
John A. Hassell
John A. Hassell McMaster University

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