James E. Bear

Overview

Best Publications

• Antagonism between Ena/VASP Proteins and Actin Filament Capping Regulates Fibroblast Motility

  James E. Bear;Tatyana M. Svitkina;Matthias Krause;Dorothy A. Schafer

  1037
  Citations

• Ena/VASP proteins: regulators of the actin cytoskeleton and cell migration.

  Matthias Krause;Erik W. Dent;James E. Bear;Joseph J. Loureiro

  834
  Citations

• PEGylated PRINT Nanoparticles: The Impact of PEG Density on Protein Binding, Macrophage Association, Biodistribution, and Pharmacokinetics

  Jillian L. Perry;Kevin G. Reuter;Marc P. Kai;Kevin P. Herlihy;Kevin P. Herlihy

  708
  Citations

• Using mechanobiological mimicry of red blood cells to extend circulation times of hydrogel microparticles

  Timothy J. Merkel;Stephen W. Jones;Kevin P. Herlihy;Farrell R. Kersey

  636
  Citations

• Engineering an improved light-induced dimer (iLID) for controlling the localization and activity of signaling proteins

  Gurkan Guntas;Ryan A. Hallett;Seth P. Zimmerman;Tishan Williams

  619
  Citations

• Arp2/3 Is Critical for Lamellipodia and Response to Extracellular Matrix Cues but Is Dispensable for Chemotaxis

  Congying Wu;Sreeja B. Asokan;Matthew E. Berginski;Elizabeth M. Haynes

  573
  Citations

• Negative Regulation of Fibroblast Motility by Ena/VASP Proteins

  James E Bear;Joseph J Loureiro;Irina Libova;Reinhard Fässler

  569
  Citations

• New insights into the regulation and cellular functions of the ARP2/3 complex

  Jeremy D. Rotty;Congying Wu;Congying Wu;James E. Bear

  552
  Citations

• The principles of directed cell migration.

  Shuvasree SenGupta;Carole A Parent;James E Bear

  414
  Citations

• Ena/VASP: towards resolving a pointed controversy at the barbed end

  James E. Bear;Frank B. Gertler

  378
  Citations

• SCAR, a WASP-related Protein, Isolated as a Suppressor of Receptor Defects in Late Dictyostelium Development

  James E. Bear;John F. Rawls;Charles L. Saxe

  337
  Citations

• Evading immune cell uptake and clearance requires PEG grafting at densities substantially exceeding the minimum for brush conformation

  Qi Yang;Stephen W. Jones;Christina L. Parker;William C. Zamboni

  275
  Citations

• Profilin-1 Serves as a Gatekeeper for Actin Assembly by Arp2/3-Dependent and -Independent Pathways

  Jeremy D. Rotty;Congying Wu;Elizabeth M. Haynes;Cristian Suarez

  270
  Citations

• Coronin 1B Coordinates Arp2/3 Complex and Cofilin Activities at the Leading Edge

  Liang Cai;Thomas W. Marshall;Andrea C. Uetrecht;Dorothy A. Schafer

  269
  Citations

• Coronin 1B Antagonizes Cortactin and Remodels Arp2/3-Containing Actin Branches in Lamellipodia

  Liang Cai;Alexander M. Makhov;Dorothy A. Schafer;James E. Bear

  269
  Citations

• The actin regulator coronin 1A is mutant in a thymic egress-deficient mouse strain and in a patient with severe combined immunodeficiency.

  Lawrence R Shiow;David W Roadcap;Kenneth Paris;Susan R Watson

  266
  Citations

• cAMP-dependent protein kinase phosphorylation of EVL, a Mena/VASP relative, regulates its interaction with actin and SH3 domains.

  Anja Lambrechts;Adam V. Kwiatkowski;Lorene M. Lanier;James E. Bear

  247
  Citations

• Coronins: the return of the crown

  Andrea C. Uetrecht;James E. Bear

  226
  Citations

• A cell-based assay for aggregation inhibitors as therapeutics of polyglutamine-repeat disease and validation in Drosophila

  Barbara L. Apostol;Alexsey Kazantsev;Simona Raffioni;Katalin Illes

  219
  Citations

• Nanoparticle clearance is governed by Th1/Th2 immunity and strain background

  Stephen W. Jones;Reid A. Roberts;Gregory R. Robbins;Jillian L. Perry

  211
  Citations