Tadaomi Takenawa

Research.com Recognitions

• 2026 - Research.com Biology and Biochemistry in Japan Leader Award
• 2025 - Research.com Biology and Biochemistry in Japan Leader Award
• 2023 - Research.com Biology and Biochemistry in Japan Leader Award

Overview

Best Publications

• The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly.

  Rajat Rohatgi;Le Ma;Hiroaki Miki;Marco Lopez

  1727
  Citations

• The WASP-WAVE protein network: connecting the membrane to the cytoskeleton.

  Tadaomi Takenawa;Shiro Suetsugu;Shiro Suetsugu

  1137
  Citations

• WAVE, a novel WASP‐family protein involved in actin reorganization induced by Rac

  Hiroaki Miki;Shiro Suetsugu;Tadaomi Takenawa

  922
  Citations

• Molecular mechanisms of invadopodium formation the role of the N-WASP–Arp2/3 complex pathway and cofilin

  Hideki Yamaguchi;Mike Lorenz;Stephan Kempiak;Corina Sarmiento

  845
  Citations

• Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

  Hiroaki Miki;Takuya Sasaki;Yoshimi Takai;Tadaomi Takenawa

  845
  Citations

• Regulation of cancer cell motility through actin reorganization

  Daisuke Yamazaki;Shusaku Kurisu;Tadaomi Takenawa

  843
  Citations

• N-WASP, a novel actin-depolymerizing protein, regulates the cortical cytoskeletal rearrangement in a PIP2-dependent manner downstream of tyrosine kinases.

  H. Miki;K. Miura;T. Takenawa

  809
  Citations

• WASP and WAVE family proteins: key molecules for rapid rearrangement of cortical actin filaments and cell movement

  T. Takenawa;H. Miki

  781
  Citations

• IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling

  Hiroaki Miki;Hideki Yamaguchi;Shiro Suetsugu;Tadaomi Takenawa

  732
  Citations

• ATP-dependent inositide phosphorylation required for Ca 2+ -activated secretion

  Jesse C. Hay;Phillip L Fisette;Glenn H Jenkins;Kiyoko Fukami

  610
  Citations

• Role of the ENTH Domain in Phosphatidylinositol-4,5-Bisphosphate Binding and Endocytosis

  Toshiki Itoh;Seizo Koshiba;Takanori Kigawa;Akira Kikuchi

  582
  Citations

• Curved EFC/F-BAR-Domain Dimers Are Joined End to End into a Filament for Membrane Invagination in Endocytosis

  Atsushi Shimada;Hideaki Niwa;Kazuya Tsujita;Shiro Suetsugu;Shiro Suetsugu

  502
  Citations

• C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins.

  Shinya Tanaka;Takashi Morishita;Yuko Hashimoto;Seisuke Hattori

  488
  Citations

• Requirement of phosphatidylinositol 4,5-bisphosphate for alpha-actinin function.

  Kiyoko Fukami;Kiyoshi Furuhashi;Masaki Inagaki;Takeshi Endo

  454
  Citations

• Coordination between the actin cytoskeleton and membrane deformation by a novel membrane tubulation domain of PCH proteins is involved in endocytosis

  Kazuya Tsujita;Shiro Suetsugu;Nobunari Sasaki;Masahiro Furutani

  451
  Citations

• Differential Roles of WAVE1 and WAVE2 in Dorsal and Peripheral Ruffle Formation for Fibroblast Cell Migration

  Shiro Suetsugu;Daisuke Yamazaki;Shusaku Kurisu;Tadaomi Takenawa

  391
  Citations

• Phosphoinositides, key molecules for regulation of actin cytoskeletal organization and membrane traffic from the plasma membrane.

  Tadaomi Takenawa;Toshiki Itoh

  389
  Citations

• WIP regulates N-WASP-mediated actin polymerization and filopodium formation

  Narcisa Martinez-Quiles;Rajat Rohatgi;Inés M. Antón;Miguel Medina

  356
  Citations

• Identification of Two Human WAVE/SCAR Homologues as General Actin Regulatory Molecules Which Associate with the Arp2/3 Complex☆

  Shiro Suetsugu;Hiroaki Miki;Tadaomi Takenawa

  333
  Citations

• Positive regulation of mu-calpain action by polyphosphoinositides.

  T C Saido;M Shibata;T Takenawa;H Murofushi

  331
  Citations