D-Index & Metrics Best Publications
Tadaomi Takenawa

Tadaomi Takenawa

Biology and Biochemistry
Japan
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 104 Citations 35,354 321 World Ranking 882 National Ranking 46

Research.com Recognitions

Awards & Achievements

2023 - Research.com Biology and Biochemistry in Japan Leader Award

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

His primary areas of investigation include Cell biology, Arp2/3 complex, Actin cytoskeleton, Cytoskeleton and MDia1. His research in Cell biology intersects with topics in Wiskott–Aldrich syndrome protein and Biochemistry. His Arp2/3 complex study integrates concerns from other disciplines, such as Actin-binding protein, Cofilin and Actin remodeling.

His biological study spans a wide range of topics, including Profilin and Actin remodeling of neurons. His Actin cytoskeleton study integrates concerns from other disciplines, such as Growth cone, Axon, Collapsin response mediator protein family and Cell membrane. His work in Cytoskeleton tackles topics such as Pseudopodia which are related to areas like Cancer cell, Mesenchyme, HT1080, RAC1 and Motility.

His most cited work include:

  • The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly. (1166 citations)
  • The WASP-WAVE protein network: connecting the membrane to the cytoskeleton. (721 citations)
  • WAVE, a novel WASP‐family protein involved in actin reorganization induced by Rac (610 citations)

What are the main themes of his work throughout his whole career to date?

Tadaomi Takenawa mainly investigates Cell biology, Biochemistry, Phosphatidylinositol, Actin and Molecular biology. The concepts of his Cell biology study are interwoven with issues in Actin remodeling, Actin cytoskeleton, Cytoskeleton, MDia1 and Arp2/3 complex. The Arp2/3 complex study combines topics in areas such as Actin-binding protein, Cofilin and Actin remodeling of neurons.

His Phosphatidylinositol study combines topics in areas such as Pleckstrin homology domain, Phospholipid, Diacylglycerol kinase and Cell growth. His Actin study combines topics from a wide range of disciplines, such as Wiskott–Aldrich syndrome protein, Lamellipodium and Mutant. His Molecular biology research integrates issues from Amino acid, Proto-oncogene tyrosine-protein kinase Src, Phosphorylation, Complementary DNA and Phospholipase C.

He most often published in these fields:

  • Cell biology (56.67%)
  • Biochemistry (33.94%)
  • Phosphatidylinositol (23.03%)

What were the highlights of his more recent work (between 2007-2017)?

  • Cell biology (56.67%)
  • Internal medicine (9.09%)
  • Actin (20.30%)

In recent papers he was focusing on the following fields of study:

Cell biology, Internal medicine, Actin, Phosphatidylinositol and Endocrinology are his primary areas of study. His Cell biology research incorporates themes from Cell migration and Cell membrane. His studies deal with areas such as Wiskott–Aldrich syndrome protein, Actin cytoskeleton, Actin remodeling, Actin nucleation and Biophysics as well as Actin.

His study looks at the relationship between Actin cytoskeleton and fields such as Endocytosis, as well as how they intersect with chemical problems. His Phosphatidylinositol research is multidisciplinary, incorporating perspectives in Pi, Pleckstrin homology domain and PTEN. In his study, Gas chromatography–mass spectrometry is inextricably linked to Biochemistry, which falls within the broad field of Insulin receptor.

Between 2007 and 2017, his most popular works were:

  • A Novel Serum Metabolomics-Based Diagnostic Approach for Colorectal Cancer (181 citations)
  • Sequential signals toward podosome formation in NIH-src cells (176 citations)
  • Involvement of Rac and Rho signaling in cancer cell motility in 3D substrates. (146 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

His scientific interests lie mostly in Cell biology, Phosphatidylinositol, Actin, Metabolomics and Internal medicine. His Cell biology study incorporates themes from Endocytosis, Membrane protein and Cell membrane. His Phosphatidylinositol research focuses on Pi and how it relates to Membrane lipids, Platelet-derived growth factor, SH3 domain, Growth factor and Cytosol.

His Actin research is multidisciplinary, incorporating elements of Transport protein, GTPase, Model organism, Actin cytoskeleton and Multicellular organism. His studies in Metabolomics integrate themes in fields like Metabolite, Gas chromatography–mass spectrometry and Stage. Tadaomi Takenawa usually deals with Gas chromatography–mass spectrometry and limits it to topics linked to Colitis and Biochemistry.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly.

Rajat Rohatgi;Le Ma;Hiroaki Miki;Marco Lopez.
Cell (1999)

1672 Citations

The WASP-WAVE protein network: connecting the membrane to the cytoskeleton.

Tadaomi Takenawa;Shiro Suetsugu;Shiro Suetsugu.
Nature Reviews Molecular Cell Biology (2007)

1052 Citations

WAVE, a novel WASP‐family protein involved in actin reorganization induced by Rac

Hiroaki Miki;Shiro Suetsugu;Tadaomi Takenawa.
The EMBO Journal (1998)

895 Citations

Molecular mechanisms of invadopodium formation the role of the N-WASP–Arp2/3 complex pathway and cofilin

Hideki Yamaguchi;Mike Lorenz;Stephan Kempiak;Corina Sarmiento.
Journal of Cell Biology (2005)

810 Citations

Regulation of cancer cell motility through actin reorganization

Daisuke Yamazaki;Shusaku Kurisu;Tadaomi Takenawa.
Cancer Science (2005)

783 Citations

Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

Hiroaki Miki;Takuya Sasaki;Yoshimi Takai;Tadaomi Takenawa.
Nature (1998)

766 Citations

N-WASP, a novel actin-depolymerizing protein, regulates the cortical cytoskeletal rearrangement in a PIP2-dependent manner downstream of tyrosine kinases.

H. Miki;K. Miura;T. Takenawa.
The EMBO Journal (1996)

746 Citations

WASP and WAVE family proteins: key molecules for rapid rearrangement of cortical actin filaments and cell movement

T. Takenawa;H. Miki.
Journal of Cell Science (2001)

741 Citations

IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling

Hiroaki Miki;Hideki Yamaguchi;Shiro Suetsugu;Tadaomi Takenawa.
Nature (2000)

710 Citations

ATP-dependent inositide phosphorylation required for Ca 2+ -activated secretion

Jesse C. Hay;Phillip L Fisette;Glenn H Jenkins;Kiyoko Fukami.
Nature (1995)

600 Citations

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