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Neuroscience

D-Index
39
Citations
5442
World Ranking
8364
National Ranking
3573

Overview

Stephen R.J. Salton is affiliated with the Icahn School of Medicine at Mount Sinai in the United States. Their research spans several interconnected domains within biochemistry, genetics, molecular biology, neuroscience, and medicine.

The primary fields of study Salton contributes to include:

  • Biochemistry, Genetics and Molecular Biology
  • Neuroscience
  • Medicine

Within these broader areas, their subfields of specialization cover:

  • Molecular Biology
  • Physiology
  • Cellular and Molecular Neuroscience
  • Developmental Neuroscience
  • Neurology

Salton's research heavily focuses on topics such as:

  • Alzheimer's disease research and treatments
  • Neuropeptides and Animal Physiology
  • Neurogenesis and neuroplasticity mechanisms
  • Protein Tyrosine Phosphatases
  • Mitochondrial Function and Pathology
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Nerve injury and regeneration

Their recent publications illustrate a sustained engagement with neurodegenerative disorders and molecular mechanisms affecting cognitive function. Selected recent papers include:

  • "Multiscale causal networks identify VGF as a key regulator of Alzheimer's disease," 2020, Nature Communications
  • "VGF-derived peptide TLQP-21 modulates microglial function through C3aR1 signaling pathways and reduces neuropathology in 5xFAD mice," 2020, Molecular Neurodegeneration
  • "An increase in VGF expression through a rapid, transcription-independent, autofeedback mechanism improves cognitive function," 2021, Translational Psychiatry
  • "Intranasal Peptide Therapeutics: A Promising Avenue for Overcoming the Challenges of Traditional CNS Drug Development," 2022, Cells
  • "Neurotrophin Crosstalk in the Etiology and Treatment of Neuropsychiatric and Neurodegenerative Disease," 2022, Frontiers in Molecular Neuroscience

Their frequent coauthors reflect collaborative engagements with researchers such as Michelle E. Ehrlich, Bin Zhang, Wei-Jye Lin, Mickaël Audrain, and Sam Gandy.

Salton's work has been published in a variety of scientific venues, with a concentration in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cells
  • Cellular and Molecular Life Sciences
  • Nature Communications
  • Molecular Neurodegeneration

Best Publications

  • Antidepressant actions of the exercise-regulated gene VGF.

    Joshua G Hunsberger;Samuel S Newton;Alicia H Bennett;Catharine H Duman

  • Targeted Deletion of the Vgf Gene Indicates that the Encoded Secretory Peptide Precursor Plays a Novel Role in the Regulation of Energy Balance

    Seung Hahm;Tooru M. Mizuno;T.John Wu;Jonathan P. Wisor

  • VGF: A Novel Role for This Neuronal and Neuroendocrine Polypeptide in the Regulation of Energy Balance ☆

    Stephen R.J. Salton;Gian-Luca Ferri;Seung Hahm;Susan E. Snyder

  • Structure of the gene encoding VGF, a nervous system-specific mRNA that is rapidly and selectively induced by nerve growth factor in PC12 cells.

    S. R. J. Salton;D. J. Fischberg;Ke-Wen Dong

  • Multiscale causal networks identify VGF as a key regulator of Alzheimer's disease.

    Noam D. Beckmann;Wei-Jye Lin;Minghui Wang;Ariella T. Cohain

  • The Neurotrophin-Inducible Gene Vgf Regulates Hippocampal Function and Behavior through a Brain-Derived Neurotrophic Factor-Dependent Mechanism

    Ozlem Bozdagi;Erin Rich;Sophie Tronel;Sophie Tronel;Masato Sadahiro

  • Processing, Distribution, and Function of VGF, a Neuronal and Endocrine Peptide Precursor

    Andrea Levi;Gian-Luca Ferri;Elizabeth Watson;Roberta Possenti

  • VGF is Required for Obesity Induced by Diet, Gold Thioglucose Treatment, and Agouti and is Differentially Regulated in Pro-Opiomelanocortin- and Neuropeptide Y-Containing Arcuate Neurons in Response to Fasting

    Seung Hahm;Csaba Fekete;Csaba Fekete;Tooru M. Mizuno;Joan Windsor

  • VGF and Its C-Terminal Peptide TLQP-62 Regulate Memory Formation in Hippocampus via a BDNF-TrkB-Dependent Mechanism.

    Wei Jye Lin;Cheng Jiang;Masato Sadahiro;Ozlem Bozdagi

  • Nerve growth factor-inducible large external (NILE) glycoprotein: studies of a central and peripheral neuronal marker

    SR Salton;C Richter-Landsberg;LA Greene;ML Shelanski

  • Comparison of RPTPζ/β, phosphacan, and trkB mRNA expression in the developing and adult rat nervous system and induction of RPTPζ/β and phosphacan mRNA following brain injury

    Susan E. Snyder;Ji Li;P. Elyse Schauwecker;Thomas H. McNeill

  • The role of neurotrophins in major depressive disorder

    Cheng Jiang;Stephen R. Salton

  • VGF function in depression and antidepressant efficacy.

    Cheng Jiang;Wei-Jye Lin;Masato Sadahiro;Benoit Labonté

  • Expression of VGF mRNA in the adult rat central nervous system

    Susan E. Snyder;Stephen R.J. Salton;Stephen R.J. Salton

  • Neuropeptide processing profile in mice lacking prohormone convertase-1.

    Hui Pan;Daniela Nanno;Fa Yun Che;Xiaorong Zhu

  • Characterization of the 5′-end region and the first two exons of the β-protein precursor gene

    Giuseppe La Fauci;Debomoy K. Lahiri;Stephen R.J. Salton;Nikolaos K. Robakis

  • VGF-derived peptide TLQP-21 modulates microglial function through C3aR1 signaling pathways and reduces neuropathology in 5xFAD mice

    Farida El Gaamouch;Mickael Audrain;Wei-Jye Lin;Wei-Jye Lin;Noam Beckmann

  • Biochemical properties of the nerve growth factor-inducible large external (Nile) glycoprotein

    SR Salton;ML Shelanski;LA Greene

  • Role of Neurotrophins in the Development and Function of Neural Circuits That Regulate Energy Homeostasis

    Samira Fargali;Masato Sadahiro;Cheng Jiang;Amy L. Frick

  • α1- and β3-Adrenergic Receptor–Mediated Mesolimbic Homeostatic Plasticity Confers Resilience to Social Stress in Susceptible Mice

    Hongxing Zhang;Dipesh Chaudhury;Alexander R. Nectow;Allyson K. Friedman

  • Complex carbohydrates of cultured PC12 pheochromocytoma cells. Effects of nerve growth factor and comparison with neonatal and mature rat brain.

    R K Margolis;S R Salton;R U Margolis

  • The messenger RNA encoding VGF, a neuronal peptide precursor, is rapidly regulated in the rat central nervous system by neuronal activity, seizure and lesion

    S. E. Snyder;H. W. Cheng;Karl D Murray;Karl D Murray;P. J. Isackson

Frequent Co-Authors

Deanna L. Benson
Deanna L. Benson Icahn School of Medicine at Mount Sinai
Tracey C. Dickson
Tracey C. Dickson University of Tasmania
Scott J. Russo
Scott J. Russo Icahn School of Medicine at Mount Sinai
Cristina M. Alberini
Cristina M. Alberini New York University
Eric J. Nestler
Eric J. Nestler Icahn School of Medicine at Mount Sinai
John E. Pintar
John E. Pintar Rutgers, The State University of New Jersey
Michelle E. Ehrlich
Michelle E. Ehrlich Icahn School of Medicine at Mount Sinai
Gabriella D'Arcangelo
Gabriella D'Arcangelo Rutgers, The State University of New Jersey
Carol A. Tamminga
Carol A. Tamminga The University of Texas Southwestern Medical Center
Eric E. Schadt
Eric E. Schadt Icahn School of Medicine at Mount Sinai

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