His primary areas of investigation include Internal medicine, Endocrinology, Ghrelin, Receptor and Hypothalamus. His research ties In situ hybridization and Internal medicine together. His Endocrinology research is mostly focused on the topic Energy homeostasis.
His Ghrelin research includes themes of Secretagogue, Growth hormone secretion and Peptide hormone. As a part of the same scientific study, he usually deals with the Receptor, concentrating on Pancreatic islets and frequently concerns with Autocrine signalling and Glucagon. His work carried out in the field of Ghrelin O-acyltransferase brings together such families of science as Growth hormone secretagogue and Leptin.
Masamitsu Nakazato mostly deals with Internal medicine, Endocrinology, Ghrelin, Transthyretin and Hypothalamus. His research brings together the fields of Gastroenterology and Internal medicine. In his study, which falls under the umbrella issue of Endocrinology, Lateral hypothalamus is strongly linked to Orexin.
Masamitsu Nakazato studies Ghrelin, focusing on Growth hormone secretagogue receptor in particular. His Transthyretin research includes elements of Amyloid, Polyneuropathy, Late onset and Amyloidosis. Masamitsu Nakazato has included themes like Central nervous system and Vagus nerve in his Hypothalamus study.
Masamitsu Nakazato mainly focuses on Internal medicine, Endocrinology, Ghrelin, Gastroenterology and Inflammation. His Internal medicine study which covers Cardiology that intersects with Parkinson's disease. His Endocrinology research incorporates themes from Proinflammatory cytokine and Receptor.
A large part of his Ghrelin studies is devoted to Growth hormone secretagogue receptor. His Gastroenterology course of study focuses on Surgery and Incidence. He combines subjects such as Adipose tissue, Pathogenesis and Skeletal muscle with his study of Inflammation.
Masamitsu Nakazato mainly investigates Internal medicine, Endocrinology, Ghrelin, Inflammation and Proinflammatory cytokine. His work in Internal medicine is not limited to one particular discipline; it also encompasses Gastroenterology. His study in Endocrinology is interdisciplinary in nature, drawing from both Receptor and AMPK.
His research integrates issues of Growth hormone secretion, Homeostasis, Orexigenic, Neuroscience and Energy metabolism in his study of Ghrelin. His Inflammation research incorporates elements of COPD, Canagliflozin, Pathogenesis and Pneumonia. The concepts of his Proinflammatory cytokine study are interwoven with issues in Skeletal muscle, Glycogen, SGLT2 Inhibitor, Adipose tissue and Sodium/Glucose Cotransporter 2.
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Ghrelin is a growth-hormone-releasing acylated peptide from stomach.
Masayasu Kojima;Hiroshi Hosoda;Yukari Date;Masamitsu Nakazato.
A role for ghrelin in the central regulation of feeding.
Masamitsu Nakazato;Noboru Murakami;Yukari Date;Masayasu Kojima.
Narcolepsy in orexin knockout mice: Molecular genetics of sleep regulation
Richard M. Chemelli;Jon T. Willie;Christopher M. Sinton;Joel K. Elmquist.
Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans.
Yukari Date;Masayasu Kojima;Hiroshi Hosoda;Akira Sawaguchi.
Upregulation of Ghrelin expression in the stomach upon fasting, insulin-induced hypoglycemia, and leptin administration.
Koji Toshinai;Muhtashan S. Mondal;Masamitsu Nakazato;Yukari Date.
Biochemical and Biophysical Research Communications (2001)
Plasma Ghrelin Levels in Lean and Obese Humans and the Effect of Glucose on Ghrelin Secretion
Tomomi Shiiya;Masamitsu Nakazato;Masanari Mizuta;Yukari Date.
The Journal of Clinical Endocrinology and Metabolism (2002)
The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats.
Yukari Date;Noboru Murakami;Koji Toshinai;Shigeru Matsukura.
Orexins, orexigenic hypothalamic peptides, interact with autonomic, neuroendocrine and neuroregulatory systems
Yukari Date;Yoichi Ueta;Hiroshi Yamashita;Hideki Yamaguchi.
Proceedings of the National Academy of Sciences of the United States of America (1999)
Ghrelin is present in pancreatic α-cells of humans and rats and stimulates insulin secretion
Yukari Date;Masamitsu Nakazato;Suzuko Hashiguchi;Katsuya Dezaki.
Elevated Circulating Level of Ghrelin in Cachexia Associated With Chronic Heart Failure Relationships Between Ghrelin and Anabolic/Catabolic Factors
Noritoshi Nagaya;Masaaki Uematsu;Masayasu Kojima;Yukari Date.
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