Hiroshi Hosoda

Overview

Best Publications

• Ghrelin is a growth-hormone-releasing acylated peptide from stomach.

  Masayasu Kojima;Hiroshi Hosoda;Yukari Date;Masamitsu Nakazato

  12467
  Citations

• Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans.

  Yukari Date;Masayasu Kojima;Hiroshi Hosoda;Akira Sawaguchi

  2430
  Citations

• Plasma Ghrelin Levels in Lean and Obese Humans and the Effect of Glucose on Ghrelin Secretion

  Tomomi Shiiya;Masamitsu Nakazato;Masanari Mizuta;Yukari Date

  1719
  Citations

• Stomach Is a Major Source of Circulating Ghrelin, and Feeding State Determines Plasma Ghrelin-Like Immunoreactivity Levels in Humans

  Hiroyuki Ariyasu;Kazuhiko Takaya;Tetsuya Tagami;Yoshihiro Ogawa

  1713
  Citations

• Ghrelin and des-acyl ghrelin: two major forms of rat ghrelin peptide in gastrointestinal tissue.

  Hiroshi Hosoda;Masayasu Kojima;Hisayuki Matsuo;Kenji Kangawa

  1341
  Citations

• Ghrelin stimulates gastric acid secretion and motility in rats.

  Yutaka Masuda;Tsuguhiko Tanaka;Norio Inomata;Norio Ohnuma

  1202
  Citations

• Ghrelin is present in pancreatic α-cells of humans and rats and stimulates insulin secretion

  Yukari Date;Masamitsu Nakazato;Suzuko Hashiguchi;Katsuya Dezaki

  870
  Citations

• Hemodynamic and hormonal effects of human ghrelin in healthy volunteers

  Noritoshi Nagaya;Masayasu Kojima;Masaaki Uematsu;Masakazu Yamagishi

  857
  Citations

• Ghrelin: discovery of the natural endogenous ligand for the growth hormone secretagogue receptor

  Masayasu Kojima;Hiroshi Hosoda;Hisayuki Matsuo;Kenji Kangawa

  723
  Citations

• Chronic administration of ghrelin improves left ventricular dysfunction and attenuates development of cardiac cachexia in rats with heart failure

  Noritoshi Nagaya;Masaaki Uematsu;Masayasu Kojima;Yoshihiko Ikeda

  690
  Citations

• Weight loss increases circulating levels of ghrelin in human obesity.

  Troels Krarup Hansen;Rolf Dall;Hiroshi Hosoda;Masayasu Kojima

  681
  Citations

• Elevated Circulating Level of Ghrelin in Cachexia Associated With Chronic Heart Failure Relationships Between Ghrelin and Anabolic/Catabolic Factors

  Noritoshi Nagaya;Masaaki Uematsu;Masayasu Kojima;Yukari Date

  595
  Citations

• Purification and characterization of rat des-Gln14-Ghrelin, a second endogenous ligand for the growth hormone secretagogue receptor.

  Hiroshi Hosoda;Masayasu Kojima;Hisayuki Matsuo;Kenji Kangawa

  551
  Citations

• Endogenous Ghrelin in Pancreatic Islets Restricts Insulin Release by Attenuating Ca2+ Signaling in β-Cells Implication in the Glycemic Control in Rodents

  Katsuya Dezaki;Hiroshi Hosoda;Masafumi Kakei;Suzuko Hashiguchi

  515
  Citations

• Kidney produces a novel acylated peptide, ghrelin.

  Kiyoshi Mori;Akihiro Yoshimoto;Kazuhiko Takaya;Kiminori Hosoda

  504
  Citations

• Structural Divergence of Human Ghrelin IDENTIFICATION OF MULTIPLE GHRELIN-DERIVED MOLECULES PRODUCED BY POST-TRANSLATIONAL PROCESSING

  Hiroshi Hosoda;Masayasu Kojima;Tsunekazu Mizushima;Shigeomi Shimizu

  457
  Citations

• Hemodynamic, renal, and hormonal effects of ghrelin infusion in patients with chronic heart failure.

  Noritoshi Nagaya;Kunio Miyatake;Masaaki Uematsu;Hideo Oya

  398
  Citations

• Increased plasma ghrelin level in lung cancer cachexia.

  Yoshito Shimizu;Noritoshi Nagaya;Takeshi Isobe;Michinori Imazu

  395
  Citations

• Structure–Activity Relationship of Ghrelin: Pharmacological Study of Ghrelin Peptides

  Masaru Matsumoto;Hiroshi Hosoda;Yasuo Kitajima;Naomi Morozumi

  370
  Citations

• Plasma ghrelin and desacyl ghrelin concentrations in renal failure

  Akihiro Yoshimoto;Kiyoshi Mori;Akira Sugawara;Masashi Mukoyama

  356
  Citations