His primary scientific interests are in Internal medicine, Endocrinology, Ghrelin, Growth hormone secretagogue receptor and Ghrelin secretion. His work deals with themes such as Serine and Peptide, which intersect with Internal medicine. In general Endocrinology study, his work on Secretagogue, Blood plasma and Cardiac output often relates to the realm of Pancreatic islets, thereby connecting several areas of interest.
His studies deal with areas such as Growth hormone secretion and Peptide hormone as well as Ghrelin. His research integrates issues of Thyroid hormone receptor, Insulin-like growth factor 1 receptor and Cell biology in his study of Growth hormone secretagogue receptor. His Ghrelin secretion study incorporates themes from Gastric motility, Stomach, Regulation of gastric function, Vagotomy and Enterochromaffin-like cell.
His primary areas of study are Internal medicine, Endocrinology, Ghrelin, Ghrelin secretion and Stomach. His study looks at the relationship between Internal medicine and topics such as Gastroenterology, which overlap with Body mass index. His Orexigenic research extends to Endocrinology, which is thematically connected.
His Ghrelin research includes themes of Growth hormone secretion and Peptide hormone. The concepts of his Growth hormone secretagogue receptor study are interwoven with issues in Growth hormone secretagogue and Energy homeostasis. His biological study spans a wide range of topics, including Cancer and Peptide.
Hiroshi Hosoda mainly focuses on Internal medicine, Endocrinology, Natriuretic peptide, Fetus and Ghrelin. His Internal medicine research incorporates themes from Gastroenterology and Cardiology. Hiroshi Hosoda interconnects Inflammation, Lung and Fibrosis in the investigation of issues within Endocrinology.
His Natriuretic peptide course of study focuses on Brain natriuretic peptide and Maintenance therapy, Prospective cohort study, Bevacizumab, Carboplatin and Lung cancer. His Ghrelin study integrates concerns from other disciplines, such as Transthyretin, Cerebral palsy, Doxorubicin, Mass index and Ischemia. His Atrial natriuretic peptide study combines topics in areas such as Receptor, Muscle hypertrophy and Immunology.
His primary areas of investigation include Internal medicine, Endocrinology, Inflammation, Natriuretic peptide and Metastasis. His work in the fields of Heart failure overlaps with other areas such as Fetus. His research combines Tadalafil and Endocrinology.
His Natriuretic peptide research is multidisciplinary, incorporating elements of Adipose tissue and Insulin resistance. His research investigates the link between Metastasis and topics such as Cancer research that cross with problems in Cell adhesion molecule, Angiotensin II, Immunohistochemistry, Cisplatin and Chemotherapy. The study incorporates disciplines such as Ghrelin, Epinephrine, End organ damage, Cell damage and Proinflammatory cytokine in addition to Oxidative stress.
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Ghrelin is a growth-hormone-releasing acylated peptide from stomach.
Masayasu Kojima;Hiroshi Hosoda;Yukari Date;Masamitsu Nakazato.
Nature (1999)
Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans.
Yukari Date;Masayasu Kojima;Hiroshi Hosoda;Akira Sawaguchi.
Endocrinology (2000)
Stomach Is a Major Source of Circulating Ghrelin, and Feeding State Determines Plasma Ghrelin-Like Immunoreactivity Levels in Humans
Hiroyuki Ariyasu;Kazuhiko Takaya;Tetsuya Tagami;Yoshihiro Ogawa.
The Journal of Clinical Endocrinology and Metabolism (2001)
Plasma Ghrelin Levels in Lean and Obese Humans and the Effect of Glucose on Ghrelin Secretion
Tomomi Shiiya;Masamitsu Nakazato;Masanari Mizuta;Yukari Date.
The Journal of Clinical Endocrinology and Metabolism (2002)
Ghrelin and des-acyl ghrelin: two major forms of rat ghrelin peptide in gastrointestinal tissue.
Hiroshi Hosoda;Masayasu Kojima;Hisayuki Matsuo;Kenji Kangawa.
Biochemical and Biophysical Research Communications (2000)
Ghrelin stimulates gastric acid secretion and motility in rats.
Yutaka Masuda;Tsuguhiko Tanaka;Norio Inomata;Norio Ohnuma.
Biochemical and Biophysical Research Communications (2000)
Ghrelin is present in pancreatic α-cells of humans and rats and stimulates insulin secretion
Yukari Date;Masamitsu Nakazato;Suzuko Hashiguchi;Katsuya Dezaki.
Diabetes (2002)
Hemodynamic and hormonal effects of human ghrelin in healthy volunteers
Noritoshi Nagaya;Masayasu Kojima;Masaaki Uematsu;Masakazu Yamagishi.
American Journal of Physiology-regulatory Integrative and Comparative Physiology (2001)
Ghrelin: discovery of the natural endogenous ligand for the growth hormone secretagogue receptor
Masayasu Kojima;Hiroshi Hosoda;Hisayuki Matsuo;Kenji Kangawa.
Trends in Endocrinology and Metabolism (2001)
Chronic administration of ghrelin improves left ventricular dysfunction and attenuates development of cardiac cachexia in rats with heart failure
Noritoshi Nagaya;Masaaki Uematsu;Masayasu Kojima;Yoshihiko Ikeda.
Circulation (2001)
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