World's Best Scientists 2026 revealed!
Masashi Yanagisawa

Masashi Yanagisawa

Award Badge
Medicine
Japan
2023

D-Index & Metrics

Medicine

D-Index
154
Citations
118736
World Ranking
985
National Ranking
16

Research.com Recognitions

  • 2023 - Research.com Medicine in Japan Leader Award
  • 2003 - Member of the National Academy of Sciences

Overview

Masashi Yanagisawa is affiliated with the University of Tsukuba in Japan and specializes in neuroscience with a strong emphasis on sleep and wakefulness research. Their work spans multiple subfields including cognitive neuroscience, experimental and cognitive psychology, endocrine and autonomic systems, cellular and molecular neuroscience, and molecular biology.

The scientist's research covers a variety of topics centered on sleep and related areas such as sleep disorders, circadian rhythm and melatonin, neuroscience and neuropharmacology, work-related fatigue, EEG and brain-computer interfaces, and neural dynamics and brain function.

Recent publications by Masashi Yanagisawa include:

  • A discrete neuronal circuit induces a hibernation-like state in rodents (2020, Nature)
  • Generation of a p16 Reporter Mouse and Its Use to Characterize and Target p16high Cells In Vivo (2020, Cell Metabolism)
  • Sparse Activity of Hippocampal Adult-Born Neurons during REM Sleep Is Necessary for Memory Consolidation (2020, Neuron)
  • Gut microbiota depletion by chronic antibiotic treatment alters the sleep/wake architecture and sleep EEG power spectra in mice (2020, Scientific Reports)
  • Kinase signalling in excitatory neurons regulates sleep quantity and depth (2022, Nature)

Yanagisawa collaborates frequently with a number of co-authors, including Hiromasa Funato, Yukiko Ishikawa, Jaehoon Seol, Chika Miyoshi, and Tsuyoshi Saitoh.

The scientist's work has been published extensively in several scientific journals and venues, with repeated contributions appearing in:

  • Scientific Reports (13 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (8 publications)
  • Proceedings of the National Academy of Sciences (6 publications)
  • PLoS ONE (6 publications)
  • SLEEP (5 publications)

Masashi Yanagisawa is recognized as a member of the National Academy of Sciences, an honor awarded in 2003.

Best Publications

  • A novel potent vasoconstrictor peptide produced by vascular endothelial cells.

    Masashi Yanagisawa;Hiroki Kurihara;Hiroki Kurihara;Sadao Kimura;Yoko Tomobe

  • Orexins and Orexin Receptors: A Family of Hypothalamic Neuropeptides and G Protein-Coupled Receptors that Regulate Feeding Behavior

    Takeshi Sakurai;Akira Amemiya;Makoto Ishii;Ichiyo Matsuzaki

  • Narcolepsy in orexin knockout mice: Molecular genetics of sleep regulation

    Richard M. Chemelli;Jon T. Willie;Christopher M. Sinton;Joel K. Elmquist

  • The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes.

    Akihiro Inoue;Masashi Yanagisawa;Sadao Kimura;Yoshitoshi Kasuya

  • Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor.

    Takeshi Sakurai;Masashi Yanagisawa;Yoh Takuwa;Hitoshi Miyazaki

  • Expression of Endothelin-1 in the Lungs of Patients with Pulmonary Hypertension

    Adel Giaid;Masashi Yanagisawa;David Langleben;René P. Michel

  • Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs

    Y. Okazaki;M. Furuno;T. Kasukawa;J. Adachi

  • Differential expression of orexin receptors 1 and 2 in the rat brain.

    Jacob N. Marcus;Carl J. Aschkenasi;Charlotte E. Lee;Richard M. Chemelli

  • Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41

    Buck S. Samuel;Abdullah Shaito;Toshiyuki Motoike;Federico E. Rey

  • Genetic Ablation of Orexin Neurons in Mice Results in Narcolepsy, Hypophagia, and Obesity

    Junko Hara;Carsten T. Beuckmann;Tadahiro Nambu;Jon T. Willie

  • Tie2-Cre transgenic mice: a new model for endothelial cell-lineage analysis in vivo.

    Yaz Y. Kisanuki;Robert E. Hammer;Jun ichi Miyazaki;S. Clay Williams

  • Distribution of orexin neurons in the adult rat brain.

    Tadahiro Nambu;Takeshi Sakurai;Katsuyoshi Mizukami;Yasuhiko Hosoya

  • Orexins, orexigenic hypothalamic peptides, interact with autonomic, neuroendocrine and neuroregulatory systems

    Yukari Date;Yoichi Ueta;Hiroshi Yamashita;Hideki Yamaguchi

  • Targeted and natural (piebald-lethal) mutations of endothelin-B receptor gene produce megacolon associated with spotted coat color in mice

    Kiminori Hosoda;Robert E. Hammer;James A. Richardson;Amy Greenstein Baynash

  • Olfactory receptor responding to gut microbiota-derived signals plays a role in renin secretion and blood pressure regulation

    Jennifer L. Pluznick;Ryan J. Protzko;Haykanush Gevorgyan;Zita Peterlin

  • ECE-1: A membrane-bound metalloprotease that catalyzes the proteolytic activation of big endothelin-1

    Dong Xu;Noriaki Emoto;Adel Giaid;Clive Slaughter

  • Interaction of endothelin-3 with endothelin-B receptor is essential for development of epidermal melanocytes and enteric neurons

    Amy Greenstein Baynash;Kiminori Hosoda;Adel Giaid;James A. Richardson

  • A missense mutation of the endothelin-B receptor gene in multigenic hirschsprung's disease

    Erik G. Puffenberger;Kiminori Hosoda;Sarah S. Washington;Kazuwa Nakao

  • Activation of peroxisome proliferator-activated receptor δ induces fatty acid β-oxidation in skeletal muscle and attenuates metabolic syndrome

    Toshiya Tanaka;Joji Yamamoto;Satoshi Iwasaki;Hiroshi Asaba

  • Vanadate is a potent (Na,K)-ATPase inhibitor found in ATP derived from muscle.

    L C Cantley;L Josephson;R Warner;M Yanagisawa

Frequent Co-Authors

Tomoh Masaki
Tomoh Masaki Kyoto University
Takeshi Sakurai
Takeshi Sakurai University of Tsukuba
Katsutoshi Goto
Katsutoshi Goto University of Tsukuba
Sadao Kimura
Sadao Kimura Chiba University
James A. Richardson
James A. Richardson The University of Texas Southwestern Medical Center
Michihiro Mieda
Michihiro Mieda Kanazawa University
Nobuhiro Suzuki
Nobuhiro Suzuki Sophia University
Satoru Takahashi
Satoru Takahashi University of Tsukuba
Robert E. Hammer
Robert E. Hammer The University of Texas Southwestern Medical Center
Jon T. Willie
Jon T. Willie Washington University in St. Louis

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring medicine in the USA opens doors to a wide variety of related online degrees and career opportunities in healthcare. For those interested in patient care but not ready for the rigors of medical school, nursing programs without teas or HESI exam requirements offer a more accessible entry point into the nursing field.

If you’re drawn to leadership roles, pursuing an online healthcare management degree can help you build key skills for administrative and policy positions in hospitals, clinics, and public health organizations. Nurses holding an ADN who want to advance their careers may consider adn to fnp bridge programs, which provide a flexible pathway to becoming a Family Nurse Practitioner.

Additionally, the healthcare sector increasingly recognizes the importance of nutrition in patient outcomes. The best online nutrition degree programs can prepare graduates for emerging careers in clinical nutrition, wellness coaching, and healthcare education.

Each of these online pathways offers flexibility for work-life balance while supporting the growing demand for skilled healthcare professionals across the industry.

Best Scientists Citing Masashi Yanagisawa

Trending Scientists

Recently Published Articles