2003 - Member of the National Academy of Sciences
His scientific interests lie mostly in Internal medicine, Endocrinology, Orexin, Endothelin receptor and Endothelin 1. The Internal medicine study combines topics in areas such as Endothelial stem cell and Transgene. His Endocrinology research includes elements of Neuropeptide, Receptor and Neuroscience.
His Orexin research incorporates themes from Wakefulness, Lateral hypothalamus and Narcolepsy. The concepts of his Endothelin receptor study are interwoven with issues in Vasoconstriction, Molecular biology and Peptide. He focuses mostly in the field of Endothelin 1, narrowing it down to matters related to Cell biology and, in some cases, Immunology.
Masashi Yanagisawa mainly investigates Internal medicine, Endocrinology, Endothelin receptor, Endothelin 1 and Orexin. His research integrates issues of Endothelial stem cell and Cardiology in his study of Internal medicine. The various areas that Masashi Yanagisawa examines in his Endocrinology study include Neuropeptide, Wakefulness and Knockout mouse.
His Endothelin receptor study incorporates themes from Molecular biology and Peptide. His Endothelin 1 research integrates issues from Pathology, Vascular smooth muscle and Cell biology. Masashi Yanagisawa has included themes like Neuroscience, Lateral hypothalamus and Narcolepsy in his Orexin study.
His primary areas of study are Internal medicine, Endocrinology, Sleep in non-human animals, Orexin and Neuroscience. His study in Endocrinology is interdisciplinary in nature, drawing from both Agonist, Endothelin receptor, Endothelin 1 and Non-rapid eye movement sleep. His Sleep in non-human animals research includes themes of Mutation, Homeostasis and Electroencephalography.
His Orexin research is multidisciplinary, incorporating perspectives in Antagonist and Insulin resistance. His Neuroscience study combines topics from a wide range of disciplines, such as Neuropeptide, Forward genetics and Phosphorylation. His Wakefulness study combines topics in areas such as Narcolepsy and Circadian rhythm.
Masashi Yanagisawa mostly deals with Internal medicine, Endocrinology, Orexin, Neuroscience and Sleep in non-human animals. Internal medicine is represented through his Neuropeptide, Orexin receptor, Receptor, Endothelin 1 and Hypothalamus research. His Endothelin 1 study integrates concerns from other disciplines, such as Autocrine signalling, Paracrine signalling, Endothelin receptor, Reabsorption and Endothelium.
Masashi Yanagisawa works on Endocrinology which deals in particular with Corticosterone. Masashi Yanagisawa combines subjects such as Ligand, Carbohydrate metabolism, Cytokine and Insulin resistance with his study of Orexin. His Wakefulness and Circadian rhythm study in the realm of Neuroscience connects with subjects such as Neuromedin S.
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A novel potent vasoconstrictor peptide produced by vascular endothelial cells.
Masashi Yanagisawa;Hiroki Kurihara;Hiroki Kurihara;Sadao Kimura;Yoko Tomobe.
Orexins and Orexin Receptors: A Family of Hypothalamic Neuropeptides and G Protein-Coupled Receptors that Regulate Feeding Behavior
Takeshi Sakurai;Akira Amemiya;Makoto Ishii;Ichiyo Matsuzaki.
The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes.
Akihiro Inoue;Masashi Yanagisawa;Sadao Kimura;Yoshitoshi Kasuya.
Proceedings of the National Academy of Sciences of the United States of America (1989)
Narcolepsy in orexin knockout mice: Molecular genetics of sleep regulation
Richard M. Chemelli;Jon T. Willie;Christopher M. Sinton;Joel K. Elmquist.
Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor.
Takeshi Sakurai;Masashi Yanagisawa;Yoh Takuwa;Hitoshi Miyazaki.
Expression of Endothelin-1 in the Lungs of Patients with Pulmonary Hypertension
Adel Giaid;Masashi Yanagisawa;David Langleben;René P. Michel.
The New England Journal of Medicine (1993)
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs
Y. Okazaki;M. Furuno;T. Kasukawa;J. Adachi.
Differential expression of orexin receptors 1 and 2 in the rat brain.
Jacob N. Marcus;Carl J. Aschkenasi;Charlotte E. Lee;Richard M. Chemelli.
The Journal of Comparative Neurology (2001)
Genetic Ablation of Orexin Neurons in Mice Results in Narcolepsy, Hypophagia, and Obesity
Junko Hara;Carsten T. Beuckmann;Tadahiro Nambu;Jon T. Willie.
Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41
Buck S. Samuel;Abdullah Shaito;Toshiyuki Motoike;Federico E. Rey.
Proceedings of the National Academy of Sciences of the United States of America (2008)
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