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Biology and Biochemistry

D-Index
136
Citations
83754
World Ranking
333
National Ranking
225

Research.com Recognitions

  • 2019 - Fellow, National Academy of Inventors
  • 1966 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Robert E. Hammer is affiliated with The University of Texas Southwestern Medical Center in the United States. Their research primarily revolves around the fields of Biochemistry, Genetics, and Molecular Biology, with notable contributions also within Medicine.

The subfields of their scientific work include Molecular Biology, Cancer Research, Oncology, Genetics, and Surgery. Their research topics span RNA modifications and cancer, RNA research and splicing, microRNA in disease regulation, circular RNAs in diseases, breast cancer treatment studies, Alzheimer's disease research and treatments, and neuroscience and neuropharmacology research.

Their publication record includes papers in various respected journals. Recent papers include:

  • "NHE6 depletion corrects ApoE4-mediated synaptic impairments and reduces amyloid plaque load," 2021, published in eLife
  • "FGF21 counteracts alcohol intoxication by activating the noradrenergic nervous system," 2023, published in Cell Metabolism
  • "Target-directed microRNA degradation regulates developmental microRNA expression and embryonic growth in mammals," 2023, published in Genes & Development
  • "Acss2/HIF-2 signaling facilitates colon cancer growth and metastasis," 2023, published in PLoS ONE
  • "Patterns of Recurrence after Neoadjuvant Therapy in Early Breast Cancer, according to the Residual Cancer Burden Index and Reductions in Neoadjuvant Treatment Intensity," 2021, published in Cancers

Frequent publication venues for their work include:

  • eLife
  • UNC Libraries
  • Cell Metabolism
  • Genes & Development
  • PLoS ONE

They have collaborated repeatedly with several coauthors, among whom are Bret M. Evers, Sarah A. Comerford, Hubert Häuser, Xunde Xian, and Joachim Herz.

Recognition received by Robert E. Hammer includes being named a Fellow of the National Academy of Inventors in 2019 and a Fellow of the American Association for the Advancement of Science (AAAS) in 1966.

Best Publications

  • Narcolepsy in orexin knockout mice: Molecular genetics of sleep regulation

    Richard M. Chemelli;Jon T. Willie;Christopher M. Sinton;Joel K. Elmquist

  • Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery.

    Shun Ishibashi;Michael S Brown;Joseph L Goldstein;Robert D. Gerard

  • Dramatic growth of mice that develop from eggs microinjected with metallothionein–growth hormone fusion genes

    Richard D. Palmiter;Ralph L. Brinster;Robert E. Hammer;Myrna E. Trumbauer

  • Synaptotagmin I: a major Ca2+ sensor for transmitter release at a central synapse.

    Martin Geppert;Yukiko Goda;Robert E. Hammer;Cai Li

  • Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41

    Buck S. Samuel;Abdullah Shaito;Toshiyuki Motoike;Federico E. Rey

  • Cholesterol and Bile Acid Metabolism Are Impaired in Mice Lacking the Nuclear Oxysterol Receptor LXRα

    Daniel J. Peet;Stephen D Turley;Wenzhen Ma;Bethany A. Janowski

  • Endocrine Regulation of the Fasting Response by PPARα-Mediated Induction of Fibroblast Growth Factor 21

    Takeshi Inagaki;Paul Dutchak;Guixiang Zhao;Xunshan Ding

  • Spontaneous inflammatory disease in transgenic rats expressing HLA-B27 and human β2m: An animal model of HLA-B27-associated human disorders

    Robert E Hammer;Shanna D. Maika;James A Richardson;Jy Ping Tang

  • Synaptic Assembly of the Brain in the Absence of Neurotransmitter Secretion

    M Verhage;A S Maia;J J Plomp;A B Brussaard

  • Production of transgenic rabbits, sheep and pigs by microinjection

    Robert E. Hammer;Vernon G. Pursel;Caird E. Rexroad;Robert J. Wall

  • The germfree state prevents development of gut and joint inflammatory disease in HLA-B27 transgenic rats

    Joel D. Taurog;James A. Richardson;JoAnne T. Croft;William A. Simmons;William A. Simmons

  • Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy

    Iichiro Shimomura;Robert E. Hammer;Shinji Ikemoto;Michael S. Brown

  • Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2.

    Marion Trommsdorff;Michael Gotthardt;Thomas Hiesberger;John Shelton

  • Tie2-Cre transgenic mice: a new model for endothelial cell-lineage analysis in vivo.

    Yaz Y. Kisanuki;Robert E. Hammer;Jun ichi Miyazaki;S. Clay Williams

  • White Fat Progenitor Cells Reside in the Adipose Vasculature

    Wei Tang;Daniel Zeve;Jae Myoung Suh;Darko Bosnakovski

  • A Neuroligin-3 Mutation Implicated in Autism Increases Inhibitory Synaptic Transmission in Mice

    Katsuhiko Tabuchi;Jacqueline Blundell;Mark R. Etherton;Robert E. Hammer

  • Decreased IRS-2 and Increased SREBP-1c Lead to Mixed Insulin Resistance and Sensitivity in Livers of Lipodystrophic and ob/ob Mice

    Iichiro Shimomura;Morihiro Matsuda;Robert E. Hammer;Yuriy Bashmakov

  • Targeted and natural (piebald-lethal) mutations of endothelin-B receptor gene produce megacolon associated with spotted coat color in mice

    Kiminori Hosoda;Robert E. Hammer;James A. Richardson;Amy Greenstein Baynash

  • Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy

    Iichiro Shimomura;Robert E. Hammer;James A. Richardson;Shinji Ikemoto

  • Interaction of endothelin-3 with endothelin-B receptor is essential for development of epidermal melanocytes and enteric neurons

    Amy Greenstein Baynash;Kiminori Hosoda;Adel Giaid;James A. Richardson

Frequent Co-Authors

James A. Richardson
James A. Richardson The University of Texas Southwestern Medical Center
Joel D. Taurog
Joel D. Taurog The University of Texas Southwestern Medical Center
Joachim Herz
Joachim Herz The University of Texas Southwestern Medical Center
Thomas C. Südhof
Thomas C. Südhof Stanford University
Joseph L. Goldstein
Joseph L. Goldstein The University of Texas Southwestern Medical Center
Michael S. Brown
Michael S. Brown The University of Texas Southwestern Medical Center
Masashi Yanagisawa
Masashi Yanagisawa University of Tsukuba
Ralph L. Brinster
Ralph L. Brinster University of Pennsylvania
Jay D. Horton
Jay D. Horton The University of Texas Southwestern Medical Center
Helen H. Hobbs
Helen H. Hobbs The University of Texas Southwestern Medical Center

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