D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 101 Citations 54,590 197 World Ranking 955 National Ranking 602

Research.com Recognitions

Awards & Achievements

2019 - Fellow, National Academy of Inventors

1966 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

Robert E. Hammer focuses on Internal medicine, Endocrinology, Cell biology, Receptor and Molecular biology. His research in Endocrinology intersects with topics in Gene targeting, Gene expression and Neuroscience. The Cell biology study combines topics in areas such as Biochemistry, Low-density lipoprotein receptor gene family, Neurotransmission and Anatomy.

His Neurotransmission research includes themes of Synaptic vesicle exocytosis, Synapsin, Synaptic vesicle and Neurotransmitter. He has included themes like Mutation, Allele, Gene, Transgene and Endothelin 3 in his Molecular biology study. His Transgene research is multidisciplinary, relying on both Bovine somatotropin and Gene isoform.

His most cited work include:

  • Narcolepsy in orexin knockout mice: Molecular genetics of sleep regulation (2591 citations)
  • Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery. (1394 citations)
  • Cholesterol and Bile Acid Metabolism Are Impaired in Mice Lacking the Nuclear Oxysterol Receptor LXRα (1275 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Molecular biology, Internal medicine, Endocrinology, Transgene and Cell biology. His Molecular biology research includes elements of Enhancer, Gene expression, Gene, Antigen and CTL*. His Internal medicine study typically links adjacent topics like Gene targeting.

His research in Endocrinology focuses on subjects like Receptor, which are connected to LDL receptor. His Transgene study which covers HLA-B27 that intersects with Arthritis and Spondyloarthropathy. As a part of the same scientific study, he usually deals with the Cell biology, concentrating on Synaptic vesicle and frequently concerns with Synaptic plasticity.

He most often published in these fields:

  • Molecular biology (33.33%)
  • Internal medicine (28.02%)
  • Endocrinology (27.05%)

What were the highlights of his more recent work (between 2003-2021)?

  • Cell biology (22.22%)
  • Internal medicine (28.02%)
  • Endocrinology (27.05%)

In recent papers he was focusing on the following fields of study:

Robert E. Hammer mainly focuses on Cell biology, Internal medicine, Endocrinology, Transgene and Receptor. The various areas that he examines in his Cell biology study include Exocytosis, Synaptic vesicle and Neurotransmitter. Robert E. Hammer combines subjects such as Glutamine and Oncology with his study of Internal medicine.

His research integrates issues of Phenotype, Orexin and Ataxin in his study of Endocrinology. His biological study spans a wide range of topics, including Embryonic stem cell, Ankylosing spondylitis, Gene expression and HLA-B27. His work deals with themes such as Alzheimer's disease, Gene targeting, Apolipoprotein E and Molecular biology, which intersect with Receptor.

Between 2003 and 2021, his most popular works were:

  • Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9 (666 citations)
  • Secreted PCSK9 decreases the number of LDL receptors in hepatocytes and inlivers of parabiotic mice (555 citations)
  • Modulation of synaptic plasticity and memory by Reelin involves differential splicing of the lipoprotein receptor Apoer2. (375 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

The scientist’s investigation covers issues in Internal medicine, Endocrinology, Gene targeting, Neuroscience and Cell biology. His Internal medicine study combines topics from a wide range of disciplines, such as Glycolipid and Endoplasmic reticulum. His Endocrinology study incorporates themes from Ceramide, Knockout mouse and Synaptic signaling.

His Gene targeting study combines topics in areas such as RNA, Phenotype, Basal and Stem cell marker. Robert E. Hammer works mostly in the field of Cell biology, limiting it down to topics relating to Neurotransmitter and, in certain cases, Neurexin, Synapse, LRRTM1, Neurotransmission and Exocytosis, as a part of the same area of interest. The concepts of his Cholesterol study are interwoven with issues in Liver X receptor and Lipid metabolism.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Narcolepsy in orexin knockout mice: Molecular genetics of sleep regulation

Richard M. Chemelli;Jon T. Willie;Christopher M. Sinton;Joel K. Elmquist.
Cell (1999)

3371 Citations

Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery.

Shun Ishibashi;Michael S Brown;Joseph L Goldstein;Robert D. Gerard.
Journal of Clinical Investigation (1993)

1737 Citations

Cholesterol and Bile Acid Metabolism Are Impaired in Mice Lacking the Nuclear Oxysterol Receptor LXRα

Daniel J. Peet;Stephen D Turley;Wenzhen Ma;Bethany A. Janowski.
Cell (1998)

1673 Citations

Spontaneous inflammatory disease in transgenic rats expressing HLA-B27 and human β2m: An animal model of HLA-B27-associated human disorders

Robert E Hammer;Shanna D. Maika;James A Richardson;Jy Ping Tang.
Cell (1990)

1632 Citations

Synaptotagmin I: A major Ca2+ sensor for transmitter release at a central synapse

Martin Geppert;Yukiko Goda;Robert E. Hammer;Cai Li.
Cell (1994)

1629 Citations

The germfree state prevents development of gut and joint inflammatory disease in HLA-B27 transgenic rats

Joel D. Taurog;James A. Richardson;JoAnne T. Croft;William A. Simmons;William A. Simmons.
Journal of Experimental Medicine (1994)

1465 Citations

Synaptic Assembly of the Brain in the Absence of Neurotransmitter Secretion

M Verhage;A S Maia;J J Plomp;A B Brussaard.
Science (2000)

1462 Citations

Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2.

Marion Trommsdorff;Michael Gotthardt;Thomas Hiesberger;John Shelton.
Cell (1999)

1440 Citations

Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy

Iichiro Shimomura;Robert E. Hammer;Shinji Ikemoto;Michael S. Brown.
Nature (1999)

1377 Citations

Tie2-Cre transgenic mice: a new model for endothelial cell-lineage analysis in vivo.

Yaz Y. Kisanuki;Robert E. Hammer;Jun ichi Miyazaki;S. Clay Williams.
Developmental Biology (2001)

1252 Citations

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