World's Best Scientists 2026 revealed!
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Joseph L. Goldstein
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Best Scientists
2025
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Biology and Biochemistry
USA
2026

D-Index & Metrics

Best Scientists

D-Index
242
Citations
219220
World Ranking
61
National Ranking
42

Biology and Biochemistry

D-Index
243
Citations
222187
World Ranking
8
National Ranking
6

Joseph L. Goldstein publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Joseph L. Goldstein sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 576 publications — 97th percentile

97% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Joseph L. Goldstein D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Joseph L. Goldstein sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 243 D-Index — 100th percentile

100% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in United States Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Biology and Biochemistry in United States Leader Award
  • 2023 - Research.com Biology and Biochemistry in United States Leader Award
  • 2022 - Research.com Biology and Biochemistry in United States Leader Award
  • 2019 - Fellow, National Academy of Inventors
  • 2007 - Member of the European Academy of Sciences
  • 2003 - Albany Medical Center Prize in Medicine and Biomedical Research
  • 2003 - Distinguished Scientist Award, American Heart Association
  • 1999 - Warren Alpert Foundation Prize For their research in the development of statins which lower the level of cholesterol in the heart.
  • 1991 - Fellow of the Royal Society, United Kingdom
  • 1990 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1988 - US President's National Medal of Science "For their historic discovery of the basic mechanisms controlling cholesterol metabolism, opening the way to a new pharmacologic approach to the treatment of cardiovascular disease, the leading cause of death and disability in the Western world.", Presented by President Reagan in a White House ceremony on July 15, 1988. Awarded jointly with Dr. Michael S. Brown, University of Texas Southwestern Medical Center.
  • 1987 - Member of the National Academy of Medicine (NAM)
  • 1985 - Nobel Prize for their discoveries concerning the regulation of cholesterol metabolism
  • 1985 - Albert Lasker Award for Basic Medical Research, Lasker Foundation
  • 1985 - William Allan Award, the American Society of Human Genetics
  • 1984 - Louisa Gross Horwitz Prize, Columbia University
  • 1981 - Canada Gairdner International Award
  • 1981 - Fellow of the American Academy of Arts and Sciences
  • 1980 - Member of the National Academy of Sciences
  • 1979 - Richard Lounsbery Award, National Academy of Sciences and the French Academy of Sciences for their work in cholesterol biosynthesis.
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Joseph L. Goldstein is affiliated with The University of Texas Southwestern Medical Center in the United States. Their research predominantly spans the fields of Biochemistry, Genetics and Molecular Biology and Medicine. Subfields of study include Molecular Biology, Surgery, Cell Biology, Endocrinology, Diabetes and Metabolism, and Endocrine and Autonomic Systems.

The scientist's main research topics encompass:

  • Cholesterol and Lipid Metabolism
  • Lipid Membrane Structure and Behavior
  • Sphingolipid Metabolism and Signaling
  • Cellular Transport and Secretion
  • Endoplasmic Reticulum Stress and Disease
  • Pancreatic Function and Diabetes
  • RNA and Protein Synthesis Mechanisms

Frequent publication venues include:

  • Proceedings of the National Academy of Sciences
  • Cell
  • Journal of Clinical Investigation
  • JAMA
  • Annals of Oncology

Frequent co-authors are:

  • Michael S. Brown
  • Michael Trinh
  • Gonçalo Vale
  • Jeffrey G. McDonald
  • Joachim Seemann

Key recent papers by Joseph L. Goldstein include:

  • "Last step in the path of LDL cholesterol from lysosome to plasma membrane to ER is governed by phosphatidylserine" (2020, Proceedings of the National Academy of Sciences)
  • "Interplay between Asters/GRAMD1s and phosphatidylserine in intermembrane transport of LDL cholesterol" (2022, Proceedings of the National Academy of Sciences)
  • "Scap structures highlight key role for rotation of intertwined luminal loops in cholesterol sensing" (2021, Cell)
  • "Unexpected role for IGF-1 in starvation: Maintenance of blood glucose" (2022, Proceedings of the National Academy of Sciences)
  • "The Spanish 1918 Flu and the COVID-19 Disease: The Art of Remembering and Foreshadowing Pandemics" (2020, Cell)

Joseph L. Goldstein has been the recipient of multiple awards throughout their career, including:

  • Fellow, National Academy of Inventors (2019)
  • Member of the European Academy of Sciences (2007)
  • Distinguished Scientist Award, American Heart Association (2003)
  • Albany Medical Center Prize in Medicine and Biomedical Research (2003)
  • Warren Alpert Foundation Prize (1999) for research in the development of statins which lower the level of cholesterol in the heart
  • Fellow of the Royal Society, United Kingdom (1991)
  • Fellow of the American Association for the Advancement of Science (AAAS) (1990)
  • US President's National Medal of Science (1988) awarded jointly with Michael S. Brown for discoveries controlling cholesterol metabolism
  • Member of the National Academy of Medicine (NAM) (1987)
  • Nobel Prize (1985) for discoveries concerning the regulation of cholesterol metabolism
  • William Allan Award, American Society of Human Genetics (1985)
  • Albert Lasker Award for Basic Medical Research (1985)
  • Louisa Gross Horwitz Prize, Columbia University (1984)
  • Canada Gairdner International Award (1981)
  • Fellow of the American Academy of Arts and Sciences (1981)
  • Member of the National Academy of Sciences (1980)
  • Richard Lounsbery Award, National Academy of Sciences and the French Academy of Sciences (1979) for work in cholesterol biosynthesis
  • Member of the Association of American Physicians

Best Publications

  • Regulation of the mevalonate pathway.

    Joseph L. Goldstein;Michael S. Brown

  • A receptor-mediated pathway for cholesterol homeostasis.

    Michael S. Brown;Joseph L. Goldstein

  • SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

    Jay D. Horton;Joseph L. Goldstein;Michael S. Brown

  • The SREBP Pathway: Regulation of Cholesterol Metabolism by Proteolysis of a Membrane-Bound Transcription Factor

    Michael S Brown;Joseph L Goldstein

  • Lipoprotein metabolism in the macrophage: Implications for cholesterol deposition in atherosclerosis

    Michael S. Brown;Joseph L. Goldstein

  • Binding Site on Macrophages that Mediates Uptake and Degradation of Acetylated Low Density Lipoprotein, Producing Massive Cholesterol Deposition

    Joseph L. Goldstein;Y. K. Ho;Sandip K. Basu;Michael S. Brown

  • The Low-Density Lipoprotein Pathway and its Relation to Atherosclerosis

    J. L. Goldstein;M. S. Brown

  • Coated pits, coated vesicles, and receptor-mediated endocytosis

    Joseph L. Goldstein;Richard G. W. Anderson;Michael S. Brown

  • Receptor-mediated endocytosis of low-density lipoprotein in cultured cells

    Joseph L. Goldstein;Sandip K. Basu;Michael S. Brown

  • Protein Sensors for Membrane Sterols

    Joseph L. Goldstein;Russell A. DeBose-Boyd;Michael S. Brown

  • Receptor-Mediated Endocytosis: Concepts Emerging from the LDL Receptor System

    Joseph L. Goldstein;Michael S. Brown;Richard G. W. Anderson;David W. Russell

  • ER Stress Induces Cleavage of Membrane-Bound ATF6 by the Same Proteases that Process SREBPs

    Jin Ye;Robert B Rawson;Ryutaro Komuro;Xi Chen

  • Hyperlipidemia in Coronary Heart Disease II. GENETIC ANALYSIS OF LIPID LEVELS IN 176 FAMILIES AND DELINEATION OF A NEW INHERITED DISORDER, COMBINED HYPERLIPIDEMIA

    Joseph L. Goldstein;Helmut G. Schrott;William R. Hazzard;Edwin L. Bierman

  • Binding and Degradation of Low Density Lipoproteins by Cultured Human Fibroblasts COMPARISON OF CELLS FROM A NORMAL SUBJECT AND FROM A PATIENT WITH HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA

    Joseph L. Goldstein;Michael S. Brown

  • Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery.

    Shun Ishibashi;Michael S Brown;Joseph L Goldstein;Robert D. Gerard

  • Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRα and LXRβ

    Joyce J. Repa;Guosheng Liang;Jiafu Ou;Yuriy Bashmakov

  • The human LDL receptor: A cysteine-rich protein with multiple Alu sequences in its mRNA

    Tokuo Yamamoto;C. Geoffrey Davis;Michael S. Brown;Wolfgang J. Schneider

  • A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood

    Michael S. Brown;Joseph L. Goldstein

  • Multivalent feedback regulation of HMG CoA reductase, a control mechanism coordinating isoprenoid synthesis and cell growth

    Michael S. Brown;Joseph L. Goldstein

  • Regulated Intramembrane Proteolysis: A Control Mechanism Conserved from Bacteria to Humans

    Michael S. Brown;Jin Ye;Robert B. Rawson;Joseph L. Goldstein

Frequent Co-Authors

Michael S. Brown
Michael S. Brown The University of Texas Southwestern Medical Center
Richard G. W. Anderson
Richard G. W. Anderson The University of Texas Southwestern Medical Center
David W. Russell
David W. Russell University of Washington
Jay D. Horton
Jay D. Horton The University of Texas Southwestern Medical Center
Robert E. Hammer
Robert E. Hammer The University of Texas Southwestern Medical Center
Joachim Herz
Joachim Herz The University of Texas Southwestern Medical Center
Thomas C. Südhof
Thomas C. Südhof Stanford University
Miguel C. Seabra
Miguel C. Seabra Universidade Nova de Lisboa
Clive A. Slaughter
Clive A. Slaughter University of Georgia
Juro Sakai
Juro Sakai University of Tokyo

External Links

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Best Scientists Citing Joseph L. Goldstein

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Publications: 117

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Publications: 113

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Antonio M. Gotto

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Ernst J. Schaefer

Tufts University

Publications: 112

Nabil G. Seidah

Nabil G. Seidah

University of Montreal

Publications: 111

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Daniel J. Rader

University of Pennsylvania

Publications: 108

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Frederick R. Maxfield

Cornell University

Publications: 105

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Andrew J. Brown

University of New South Wales

Publications: 105

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Louis M. Havekes

Leiden University Medical Center

Publications: 104

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University of California, San Francisco

Publications: 103

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Michael Aviram

Technion – Israel Institute of Technology

Publications: 103

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