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Medicine

D-Index
112
Citations
35463
World Ranking
5206
National Ranking
198

Overview

Louis M. Havekes is affiliated with Leiden University Medical Center in the Netherlands. Their research spans multiple disciplines within the biomedical sciences, with a particular focus on biochemistry, genetics, and molecular biology, as well as medicine.

Their published work covers a range of interconnected topics including lipid metabolism and disorders, cancer, hypoxia, metabolism, diabetes, and cancer. These research interests reflect an integration of metabolic and cardiovascular health with oncological mechanisms.

Key subfields addressed by Havekes include cardiology and cardiovascular medicine, cancer research, and molecular biology. This interdisciplinary approach positions their research at the intersection of disease pathophysiology and molecular mechanisms.

Havekes has contributed to the scientific literature with research published notably in UNC Libraries. A recent publication titled "ApoE2-associated hypertriglyceridemia is ameliorated by increased levels of apoA-V but unaffected by apoC-III deficiency" was released in 2020. This work explores genetic factors influencing lipid metabolism.

Collaborations form an important part of Havekes' scientific activity. Frequent coauthors include:

  • Gery Gerritsen
  • Caroline C. van der Hoogt
  • Frank G. Schaap
  • Peter J. Voshol
  • Kyriakos E. Kypreos

These partnerships suggest active engagement with a network of researchers contributing to studies in related biomedical fields. The frequent interaction with colleagues across genetics, molecular biology, and clinical medicine further illustrates a multidisciplinary research environment.

Havekes' expertise centers on elucidating molecular and genetic drivers of complex metabolic and cardiovascular conditions, as well as their interplay with cancer biology. This positions their research as relevant to understanding systemic disease mechanisms from molecular to clinical levels.

Best Publications

  • Role of ApoCs in Lipoprotein Metabolism Functional Differences Between ApoC1, ApoC2, and ApoC3

    Miek C. Jong;Marten H. Hofker;Louis M. Havekes

  • Postprandial lipoprotein metabolism in normolipidemic men with and without coronary artery disease.

    P H Groot;W A van Stiphout;X H Krauss;H Jansen

  • Stimulation of lipogenesis by pharmacological activation of the liver X receptor leads to production of large, triglyceride-rich very low density lipoprotein particles

    Aldo Grefhorst;Baukje M Elzinga;Peter J Voshol;Torsten Plösch

  • Apolipoprotein E4 allele in a population-based study of early-onset Alzheimer's disease

    C.M. van Duijn;P. de Knijff;M. Cruts;A. Wehnert;A. Wehnert

  • Establishment of a General NAFLD Scoring System for Rodent Models and Comparison to Human Liver Pathology

    Wen Liang;Aswin L. Menke;Ann Driessen;Ger H. Koek

  • Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development.

    Jimmy F. P. Berbée;Mariëtte R Boon;P. Padmini S. J. Khedoe;Alexander Bartelt

  • Selective parasympathetic innervation of subcutaneous and intra-abdominal fat — functional implications

    Felix Kreier;Eric Fliers;Peter J. Voshol;Corbert G. Van Eden

  • Metabolomics in the context of systems biology: bridging traditional Chinese medicine and molecular pharmacology.

    Mei Wang;Robert-Jan A. N. Lamers;Robert-Jan A. N. Lamers;Henrie A. A. J. Korthout;Joop H. J. van Nesselrooij

  • ApoAV reduces plasma triglycerides by inhibiting very low density lipoprotein-triglyceride (VLDL-TG) production and stimulating lipoprotein lipase-mediated VLDL-TG hydrolysis.

    Frank G. Schaap;Patrick C.N. Rensen;Peter J. Voshol;Carlos Vrins

  • Hepatic Steatosis: A Mediator of the Metabolic Syndrome: Lessons From Animal Models

    M. den Boer;P.J. Voshol;F. Kuipers;L.M. Havekes

  • Diet-induced hyperlipoproteinemia and atherosclerosis in apolipoprotein E3-Leiden transgenic mice.

    B. J. M. Van Vlijmen;A. M. J. M. Van Den Maagdenberg;M. J. J. Gijbels;H. Van Der Boom

  • Macrophage scavenger receptor class A: A multifunctional receptor in atherosclerosis.

    M.P.J. de Winther;K.W. van Dijk;L.M. Havekes;M.H. Hofker

  • A rapid micromethod for apolipoprotein E phenotyping directly in serum

    L M Havekes;P de Knijff;U Beisiegel;J Havinga

  • The expression of type III hyperlipoproteinemia: involvement of lipolysis genes

    Peter Henneman;Femke Van Der Sman-De Beer;Payman Hanifi Moghaddam;Petra Huijts

  • PPARα governs glycerol metabolism

    David Patsouris;Stéphane Mandard;Peter J. Voshol;Pascal Escher

  • Interactions between inflammation and lipid metabolism: relevance for efficacy of anti-inflammatory drugs in the treatment of atherosclerosis.

    Janna A. van Diepen;Jimmy F.P. Berbée;Jimmy F.P. Berbée;Louis M. Havekes;Patrick C.N. Rensen

  • Transgenic mice carrying the apolipoprotein E3-Leiden gene exhibit hyperlipoproteinemia.

    A. M. J. M. Van Den Maagdenberg;M. H. Hofker;P. J. A. Krimpenfort;I. De Bruijn

  • Induction of Atherosclerotic Plaque Rupture in Apolipoprotein E−/− Mice After Adenovirus-Mediated Transfer of p53

    Jan H. Von Der Thüsen;Bart J. M. Van Vlijmen;Rob C. Hoeben;Mark M. Kockx

  • Cholesteryl Ester Transfer Protein Decreases High-Density Lipoprotein and Severely Aggravates Atherosclerosis in APOE*3-Leiden Mice

    Marit Westerterp;Caroline C van der Hoogt;Willeke de Haan;Erik H Offerman

  • Low Density Lipoprotein Receptor Internalizes Low Density and Very Low Density Lipoproteins That Are Bound to Heparan Sulfate Proteoglycans via Lipoprotein Lipase

    M. Mulder;P. Lombardi;H. Jansen;T.J.C. van Berkel

Frequent Co-Authors

Patrick C. N. Rensen
Patrick C. N. Rensen Leiden University Medical Center
Johannes A. Romijn
Johannes A. Romijn University of Amsterdam
Ko Willems van Dijk
Ko Willems van Dijk Leiden University Medical Center
Rune R. Frants
Rune R. Frants Leiden University
Marten H. Hofker
Marten H. Hofker University Medical Center Groningen
Hans M.G. Princen
Hans M.G. Princen Netherlands Organisation for Applied Scientific Research
Hanno Pijl
Hanno Pijl Leiden University Medical Center
Folkert Kuipers
Folkert Kuipers University Medical Center Groningen
J. Wouter Jukema
J. Wouter Jukema Leiden University Medical Center
Theo J.C. Van Berkel
Theo J.C. Van Berkel Leiden University

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