World's Best Scientists 2026 revealed!

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Immunology

D-Index
57
Citations
10461
World Ranking
3636
National Ranking
1680

Overview

James C. Zimring is affiliated with the University of Washington in the United States. Their research predominantly spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a strong emphasis on physiology, hematology, molecular biology, and genetics.

They have contributed significantly to topics related to erythrocyte function and pathophysiology, blood groups and transfusion, neonatal health and biochemistry, hemoglobinopathies and related disorders, metabolism and genetic disorders, hemoglobin structure and function, and heme oxygenase-1 and carbon monoxide.

Their frequent co-authors include:

  • Angelo D'Alessandro
  • Ariel Hay
  • Travis Nemkov
  • Monika Dzieciątkowska
  • Krystalyn E. Hudson

The scientist's recent papers illustrate a focus on COVID-19's impact on blood and metabolism, highlighting changes in protein and lipid structures as well as coagulation and complement pathways. Notable publications include:

  • "COVID-19 infection alters kynurenine and fatty acid metabolism, correlating with IL-6 levels and renal status," 2020, JCI Insight
  • "Evidence of Structural Protein Damage and Membrane Lipid Remodeling in Red Blood Cells from COVID-19 Patients," 2020, Journal of Proteome Research
  • "Serum Proteomics in COVID-19 Patients: Altered Coagulation and Complement Status as a Function of IL-6 Level," 2020, Journal of Proteome Research
  • "Donor sex, age and ethnicity impact stored red blood cell antioxidant metabolism through mechanisms in part explained by glucose 6-phosphate dehydrogenase levels and activity," 2020, Haematologica
  • "Donor glucose-6-phosphate dehydrogenase deficiency decreases blood quality for transfusion," 2020, Journal of Clinical Investigation

The venues frequently chosen for publishing include:

  • Transfusion
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Blood
  • Haematologica
  • Journal of Clinical Investigation

James C. Zimring has also contributed to the academic literature through book publications, with a noted title published by Columbia University Press:

  • Partial Truths, 2022

Best Publications

  • Transfusion of red blood cells after prolonged storage produces harmful effects that are mediated by iron and inflammation

    Eldad A. Hod;Eldad A. Hod;Ning Zhang;Set A. Sokol;Boguslaw S. Wojczyk

  • COVID-19 infection alters kynurenine and fatty acid metabolism, correlating with IL-6 levels and renal status.

    Tiffany Thomas;Davide Stefanoni;Julie A. Reisz;Travis Nemkov

  • Transfusion of human volunteers with older, stored red blood cells produces extravascular hemolysis and circulating non–transferrin-bound iron

    Eldad A. Hod;Gary M. Brittenham;Genia B. Billote;Richard O. Francis

  • Human herpesvirus 8 encodes an interferon regulatory factor (IRF) homolog that represses IRF-1-mediated transcription.

    James C. Zimring;Stephen Goodbourn;Margaret K. Offermann

  • Evidence of Structural Protein Damage and Membrane Lipid Remodeling in Red Blood Cells from COVID-19 Patients.

    Tiffany Thomas;Davide Stefanoni;Monika Dzieciatkowska;Aaron Issaian

  • Affinity of human IgG subclasses to mouse Fc gamma receptors

    Gillian Dekkers;Arthur E. H. Bentlage;Tamara C. Stegmann;Heather L. Howie

  • Serum Proteomics in COVID-19 Patients: Altered Coagulation and Complement Status as a Function of IL-6 Level.

    Angelo D’Alessandro;Tiffany Thomas;Monika Dzieciatkowska;Ryan C. Hill

  • Initiation and Regulation of Complement during Hemolytic Transfusion Reactions

    Sean R. Stowell;Anne M. Winkler;Cheryl L. Maier;C. Maridith Arthur

  • Recipient inflammation affects the frequency and magnitude of immunization to transfused red blood cells

    Jeanne E. Hendrickson;Maxime Desmarets;Seema S. Deshpande;Traci E. Chadwick

  • A novel mouse model of red blood cell storage and posttransfusion in vivo survival.

    Christopher R. Gilson;Teresa S. Kraus;Eldad A. Hod;Jeanne E. Hendrickson

  • Inflammation enhances consumption and presentation of transfused RBC antigens by dendritic cells.

    Jeanne E. Hendrickson;Traci E. Chadwick;John D. Roback;Christopher D. Hillyer

  • Testosterone-dependent sex differences in red blood cell hemolysis in storage, stress and disease

    Tamir Kanias;Derek Sinchar;David Osei-Hwedieh;Jeffrey J. Baust

  • Established and theoretical factors to consider in assessing the red cell storage lesion

    James C. Zimring

  • Minor histocompatibility antigens on transfused leukoreduced units of red blood cells induce bone marrow transplant rejection in a mouse model.

    Maxime Desmarets;Chantel M. Cadwell;Kenneth R. Peterson;Renee Neades

  • Glucose-6-phosphate dehydrogenase deficiency in transfusion medicine: the unknown risks.

    Richard O. Francis;Jeffrey S. Jhang;Huy P. Pham;Eldad A. Hod

  • Bridging channel dendritic cells induce immunity to transfused red blood cells

    Samuele Calabro;Antonia Gallman;Uthaman Gowthaman;Dong Liu

  • Blood donation and blood transfusion: special considerations for African Americans.

    Beth H. Shaz;James C. Zimring;Derrick G. Demmons;Christopher D. Hillyer

  • Donor glucose-6-phosphate dehydrogenase deficiency decreases blood quality for transfusion.

    Richard O. Francis;Angelo D’Alessandro;Andrew Eisenberger;Mark Soffing

  • Red blood cells as an organ? How deep omics characterization of the most abundant cell in the human body highlights other systemic metabolic functions beyond oxygen transport.

    Travis Nemkov;Julie A. Reisz;Yang Xia;James C. Zimring

  • Nonhemolytic antibody-induced loss of erythrocyte surface antigen.

    James C. Zimring;Gregory A. Hair;Traci E. Chadwick;Seema S. Deshpande

  • Transfusion in the absence of inflammation induces antigen-specific tolerance to murine RBCs.

    Nicole H. Smith;Eldad A. Hod;Eldad A. Hod;Steven L. Spitalnik;Steven L. Spitalnik;James C. Zimring

  • Activation of the Double‐Stranded‐RNA‐Activated Protein Kinase and Induction of Vascular Cell Adhesion Molecule‐1 by Poly (I) · Poly (C) in Endothelial Cells

    Margaret K. Offermann;James Zimring;Kenneth H. Mellits;M. Kelly Hagan

Frequent Co-Authors

Jeanne E. Hendrickson
Jeanne E. Hendrickson Yale University
Steven L. Spitalnik
Steven L. Spitalnik Columbia University
Angelo D'Alessandro
Angelo D'Alessandro University of Colorado Denver
Travis Nemkov
Travis Nemkov University of Colorado Denver
Michael P. Busch
Michael P. Busch University of California, San Francisco
Kirk C. Hansen
Kirk C. Hansen University of Colorado Anschutz Medical Campus
Jason P. Acker
Jason P. Acker University of Alberta
Mark T. Gladwin
Mark T. Gladwin University of Pittsburgh
Kirk A. Easley
Kirk A. Easley Emory University

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