Hans M.G. Princen

Best Publications

• Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease

  Frederick E Dewey;Viktoria Gusarova;Richard L Dunbar;Colm T O'Dushlaine

  875
  Citations

• Mouse Models for Atherosclerosis and Pharmaceutical Modifiers

  Susanne Zadelaar;Robert Kleemann;Lars Verschuren;Jitske de Vries-Van der Weij

  693
  Citations

• Supplementation with vitamin E but not beta-carotene in vivo protects low density lipoprotein from lipid peroxidation in vitro. Effect of cigarette smoking.

  H. M. G. Princen;G. Van Poppel;C. Vogelezang;R. Buytenhek

  467
  Citations

• Tumor necrosis factor increases the production of plasminogen activator inhibitor in human endothelial cells in vitro and in rats in vivo

  V.W.M. van Hinsbergh;T. Kooistra;E.A. van den Berg;H.M.G. Princen

  413
  Citations

• Fibrates down-regulate IL-1-stimulated C-reactive protein gene expression in hepatocytes by reducing nuclear p50-NFκB-C/EBP-β complex formation

  Robert Kleemann;Philippe P. Gervois;Philippe P. Gervois;Lars Verschuren;Lars Verschuren;Bart Staels;Bart Staels

  282
  Citations

• Fibrates Suppress Bile Acid Synthesis via Peroxisome Proliferator–Activated Receptor-α–Mediated Downregulation of Cholesterol 7α-Hydroxylase and Sterol 27-Hydroxylase Expression

  Sabine M. Post;Hélène Duez;Philippe P. Gervois;Bart Staels

  276
  Citations

• Supplementation With Low Doses of Vitamin E Protects LDL From Lipid Peroxidation in Men and Women

  H.M.G. Princen;W. van Duyvenvoorde;R. Buytenhek;A. van der Laarse

  271
  Citations

• Plasminogen activator inhibitor 1: biosynthesis and mRNA level are increased by insulin in cultured human hepatocytes.

  T. Kooistra;P. J. Bosma;H. A. M. Tons;A. P. Van Den Berg

  258
  Citations

• Evidence for anti-inflammatory activity of statins and PPARα activators in human C-reactive protein transgenic mice in vivo and in cultured human hepatocytes in vitro

  Robert Kleemann;Lars Verschuren;Bert-Jan de Rooij;Jan Lindeman

  244
  Citations

• Niacin Increases HDL by Reducing Hepatic Expression and Plasma Levels of Cholesteryl Ester Transfer Protein in APOE*3Leiden.CETP Mice

  José W.A. van der Hoorn;Willeke de Haan;Jimmy F.P. Berbée;Louis M. Havekes

  237
  Citations

• Rosuvastatin reduces atherosclerosis development beyond and independent of its plasma cholesterol-lowering effect in APOE*3-Leiden transgenic mice: evidence for antiinflammatory effects of rosuvastatin

  Robert Kleemann;Hans M.G. Princen;Jef J. Emeis;J. Wouter Jukema

  235
  Citations

• No Effect of Consumption of Green and Black Tea on Plasma Lipid and Antioxidant Levels and on LDL Oxidation in Smokers

  H.M.G. Princen;W. van Duyvenvoorde;R. Buytenhek;C. Blonk

  227
  Citations

• Strong decrease of high sensitivity C-reactive protein with high-dose atorvastatin in patients with type 2 diabetes mellitus

  M.A van de Ree;M.V Huisman;H.M.G Princen;A.E Meinders

  227
  Citations

• Alirocumab inhibits atherosclerosis, improves the plaque morphology, and enhances the effects of a statin

  Susan Kühnast;Susan Kühnast;José W. A. van der Hoorn;José W. A. van der Hoorn;Elsbet J. Pieterman;Anita M. van den Hoek

  227
  Citations

• Safety of long-term consumption of plant sterol esters-enriched spread

  H F J Hendriks;E J Brink;G W Meijer;H M G Princen

  224
  Citations

• The AT04A vaccine against proprotein convertase subtilisin/kexin type 9 reduces total cholesterol, vascular inflammation, and atherosclerosis in APOE*3Leiden.CETP mice

  Christine Landlinger;Marianne G. Pouwer;Claudia Juno;José W.A. van der Hoorn

  219
  Citations

• Fibrates suppress fibrinogen gene expression in rodents via activation of the peroxisome proliferator-activated receptor-α

  Maaike Kockx;Philippe P. Gervois;Philippe Poulain;Bruno Derudas

  202
  Citations

• Inhibition of plasminogen activators by conditioned medium of human hepatocytes and hepatoma cell line Hep G2.

  Sprengers Ed;Princen Hm;Kooistra T;van Hinsbergh Vw

  179
  Citations

• Serum carotenoids and vitamins in relation to markers of endothelial function and inflammation.

  Wendy M R van Herpen-Broekmans;Ineke A A Klöpping-Ketelaars;Michiel L Bots;Cornelis Kluft

  179
  Citations

• Retinoids increase human apo C-III expression at the transcriptional level via the retinoid X receptor. Contribution to the hypertriglyceridemic action of retinoids.

  N. Vu-Dac;P. Gervois;I.P. Torra;J.C. Fruchart

  173
  Citations