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Irène Juhan-Vague

Irène Juhan-Vague

D-Index & Metrics

Medicine

D-Index
92
Citations
29480
World Ranking
11355
National Ranking
348

Overview

Irène Juhan-Vague is affiliated with Hôpital de la Timone in France and has a research focus primarily within the field of Medicine, specifically addressing topics related to reproductive health, autoimmune diseases, and thrombotic complications.

The main subjects of their work include:

  • Reproductive System and Pregnancy
  • Systemic Lupus Erythematosus Research
  • Pregnancy and preeclampsia studies
  • Venous Thromboembolism Diagnosis and Management
  • Diagnosis and Treatment of Venous Diseases
  • Atrial Fibrillation Management and Outcomes
  • Pregnancy and Medication Impact

Juhan-Vague has contributed to a number of research papers, demonstrating engagement with multiple topics around maternal health, autoimmune conditions, and venous thromboembolism. Recent publications include:

  • "Extended treatment of venous thromboembolism with reduced-dose versus full-dose direct oral anticoagulants in patients at high risk of recurrence: a non-inferiority, multicentre, randomised, open-label, blinded endpoint trial," 2025, The Lancet
  • "Global comment on the use of hydroxychloroquine during the periconception period and pregnancy in women with autoimmune diseases," 2023, The Lancet Rheumatology
  • "Characterisation of a high-risk profile for maternal thrombotic and severe haemorrhagic complications in pregnant women with antiphospholipid syndrome in France (GR2): a multicentre, prospective, observational study," 2022, The Lancet Rheumatology
  • "Whole exome sequencing, a hypothesis-free approach to investigate recurrent early miscarriage," 2021, Reproductive BioMedicine Online
  • "AB0433 HIGH RISK OF MATERNAL THROMBOTIC AND SEVERE HEMORRHAGIC COMPLICATIONS IN 119 PROSPECTIVE PREGNANCIES ASSOCIATED WITH ANTIPHOSPHOLIPID SYNDROME (GR2 STUDY)," 2020, Annals of the Rheumatic Diseases

Their research often appears in recognized medical journals, with frequent publication venues including:

  • The Lancet Rheumatology
  • The Lancet
  • Reproductive BioMedicine Online
  • Annals of the Rheumatic Diseases
  • EMC - Ginecología-Obstetricia

Collaborations form an important part of Juhan-Vague's scholarly work. Frequent co-authors include:

  • Claire de Moreuil
  • Françis Couturaud
  • N. Costedoat-Chalumeau
  • V. Queyrel
  • Y. Benhamou

Subfields of study related to their research span Public Health, Environmental and Occupational Health, Rheumatology, Immunology, Obstetrics and Gynecology, and Internal Medicine. This range highlights an interdisciplinary approach addressing complex issues concerning pregnancy-related complications and autoimmune disease management.

Best Publications

  • Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality: an individual participant meta-analysis.

    J Danesh;S Lewington;S G Thompson;Lowe Gdo.

  • Production of plasminogen activator inhibitor 1 by human adipose tissue : Possible link between visceral fat accumulation and vascular disease

    M C Alessi;F Peiretti;P Morange;M Henry

  • Measurement of plasminogen activator inhibitor 1 in biologic fluids with a murine monoclonal antibody-based enzyme-linked immunosorbent assay.

    Paul Declerck;M C Alessi;M Verstreken;E K O Kruithof

  • Increased plasma plasminogen activator inhibitor 1 levels. A possible link between insulin resistance and atherothrombosis

    I. Juhan-Vague;M. C. Alessi;P. Vague

  • Fibrinolytic Factors and the Risk of Myocardial Infarction or Sudden Death in Patients With Angina Pectoris

    Ire`ne Juhan-Vague;Stephen D.M. Pyke;Marie Christine Alessi;Jorgen Jespersen

  • Correlation Between Blood Fibrinolytic Activity, Plasminogen Activator Inhibitor Level, Plasma Insulin Level, and Relative Body Weight in Normal and Obese Subjects

    Philippe Vague;Irène Juhan-Vague;Marie Francoise Aillaud;Christian Badier

  • PAI-1, Obesity, Insulin Resistance and Risk of Cardiovascular Events

    I Juhan-Vague;M C Alessi

  • Deficient t-PA release and elevated PA inhibitor levels in patients with spontaneous or recurrent deep venous thrombosis.

    I Juhan-Vague;J Valadier;M C Alessi;M F Aillaud

  • C-Reactive Protein, Interleukin-6, and Fibrinogen as Predictors of Coronary Heart Disease The PRIME Study

    Gérald Luc;Jean-Marie Bard;Irène Juhan-Vague;Jean Ferrieres

  • Involvement of the hemostatic system in the insulin resistance syndrome. A study of 1500 patients with angina pectoris. The ECAT Angina Pectoris Study Group.

    I Juhan-Vague;S G Thompson;J Jespersen

  • PAI-1 and the Metabolic Syndrome. Links, Causes, and Consequences

    Marie-Christine Alessi;Irène Juhan-Vague

  • Plasminogen activator inhibitor 1, transforming growth factor-beta1, and BMI are closely associated in human adipose tissue during morbid obesity.

    Marie-Christine Alessi;Delphine Bastelica;Pierre Morange;Bruno Berthet

  • Plasminogen activator inhibitor-1, inflammation, obesity, insulin resistance and vascular risk.

    Juhan-Vague I;Alessi Mc;Mavri A;Mavri A;Morange Pe

  • C3H/HeJ mice carrying a toll-like receptor 4 mutation are protected against the development of insulin resistance in white adipose tissue in response to a high-fat diet

    M. Poggi;D. Bastelica;P. Gual;M. A. Iglesias

  • Increased plasminogen activator inhibitor activity in non insulin dependent diabetic patients--relationship with plasma insulin.

    I Juhan-Vague;C Roul;M C Alessi;J P Ardissone

  • The Effect of Metformin on the Metabolic Abnormalities Associated With Upper-Body Fat Distribution. BIGPRO Study Group

    A Fontbonne;M A Charles;I Juhan-Vague;J M Bard

  • Insulin stimulates the synthesis of plasminogen activator inhibitor 1 by the human hepatocellular cell line Hep G2.

    M C Alessi;I Juhan-Vague;T Kooistra;Paul Declerck

  • Common susceptibility alleles are unlikely to contribute as strongly as the FV and ABO loci to VTE risk: results from a GWAS approach

    David-Alexandre Trégouët;Simon Heath;Noémie Saut;Christine Biron-Andreani

  • Plasma levels of a specific inhibitor of tissue-type plasminogen activator (and urokinase) in normal and pathological conditions.

    I. Juhan-Vague;B. Moerman;F. De Cock;M.F. Aillaud

  • Contributions of Depressive Mood and Circulating Inflammatory Markers to Coronary Heart Disease in Healthy European Men. The Prospective Epidemiological Study of Myocardial Infarction (PRIME)

    J.P. Empana;D.H. Sykes;G. Luc;I. Juhan-Vague

Frequent Co-Authors

Marie-Christine Alessi
Marie-Christine Alessi Aix-Marseille University
Dominique Arveiler
Dominique Arveiler University of Strasbourg
Jean Ferrières
Jean Ferrières Federal University of Toulouse Midi-Pyrénées
David-Alexandre Trégouët
David-Alexandre Trégouët University of Bordeaux
Pierre Ducimetière
Pierre Ducimetière Université Paris Cité
Laurence Tiret
Laurence Tiret Sorbonne University
Desire Collen
Desire Collen KU Leuven
Paul Declerck
Paul Declerck KU Leuven
Alun Evans
Alun Evans Queen's University Belfast
Maurizio Margaglione
Maurizio Margaglione University of Foggia

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