World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
81
Citations
26408
World Ranking
3846
National Ranking
1905

Research.com Recognitions

  • 2012 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

George B. Witman is affiliated with the University of Massachusetts Chan Medical School in the United States. Their research spans multiple fields, primarily focusing on biochemistry, genetics, and molecular biology, with additional work in physics and astronomy.

Their work covers several subfields, including genetics, molecular biology, condensed matter physics, cell biology, and pediatrics, perinatology, and child health. Central topics in their research include genetic and kidney cyst diseases, micro and nano robotics, microtubule and mitosis dynamics, protist diversity and phylogeny, CRISPR and genetic engineering, photosynthetic processes and mechanisms, and fetal and pediatric neurological disorders.

Frequent co-authors collaborating with George B. Witman are:

  • Yuqing Hou
  • Karl F. Lechtreck
  • Xi Cheng
  • Tomohiro Kubo
  • Lei Zhao

George B. Witman's recent papers include:

  • "TIM, a targeted insertional mutagenesis method utilizing CRISPR/Cas9 in Chlamydomonas reinhardtii," 2020, PLoS ONE
  • "Consensus nomenclature for dyneins and associated assembly factors," 2022, The Journal of Cell Biology
  • "Diffusion rather than intraflagellar transport likely provides most of the tubulin required for axonemal assembly in Chlamydomonas," 2020, Journal of Cell Science
  • "Chlamydomonas FAP70 is a component of the previously uncharacterized ciliary central apparatus projection C2a," 2021, Journal of Cell Science
  • "Structural organization of the C1b projection within the ciliary central apparatus," 2021, Journal of Cell Science

Their work has been published frequently in the following venues:

  • Journal of Cell Science
  • PLoS ONE
  • The Journal of Cell Biology
  • Cytoskeleton
  • bioRxiv (Cold Spring Harbor Laboratory)

George B. Witman received recognition as a Fellow of the American Association for the Advancement of Science (AAAS) in 2012.

Best Publications

  • The Chlamydomonas Genome Reveals the Evolution of Key Animal and Plant Functions

    Sabeeha S. Merchant;Simon E. Prochnik;Olivier Vallon;Elizabeth H. Harris

  • Chlamydomonas IFT88 and Its Mouse Homologue, Polycystic Kidney Disease Gene Tg737, Are Required for Assembly of Cilia and Flagella

    Gregory J. Pazour;Bethany L. Dickert;Yvonne Vucica;E. Scott Seeley

  • Proteomic analysis of a eukaryotic cilium

    Gregory J. Pazour;Nathan S. Agrin;John D. Leszyk;George B. Witman

  • Polycystin-2 localizes to kidney cilia and the ciliary level is elevated in orpk mice with polycystic kidney disease

    Gregory J. Pazour;Jovenal T. San Agustin;John A. Follit;Joel L. Rosenbaum

  • Chlamydomonas flagella. I. Isolation and electrophoretic analysis of microtubules, matrix, membranes, and mastigonemes.

    George B. Witman;K. Carlson;J. Berliner;Joel L. Rosenbaum

  • The intraflagellar transport protein, IFT88, is essential for vertebrate photoreceptor assembly and maintenance.

    Gregory J. Pazour;Sheila A. Baker;James A. Deane;Douglas G. Cole

  • The vertebrate primary cilium is a sensory organelle.

    Gregory J Pazour;George B Witman

  • The DHC1b (DHC2) Isoform of Cytoplasmic Dynein Is Required for Flagellar Assembly

    Gregory J. Pazour;Bethany L. Dickert;George B. Witman

  • A Dynein Light Chain Is Essential for the Retrograde Particle Movement of Intraflagellar Transport (IFT)

    Gregory J. Pazour;Curtis G. Wilkerson;George B. Witman

  • Chlamydomonas flagellar mutants lacking radial spokes and central tubules. Structure, composition, and function of specific axonemal components.

    George B. Witman;J. Plummer;Greta Sander

  • CEP290 tethers flagellar transition zone microtubules to the membrane and regulates flagellar protein content

    Branch Craige;Che-Chia Tsao;Dennis R. Diener;Yuqing Hou

  • Correction: Corrigendum: TCTEX1D2 mutations underlie Jeune asphyxiating thoracic dystrophy with impaired retrograde intraflagellar transport

    Miriam Schmidts;Yuqing Hou;Claudio R. Cortes;Dorus A. Mans

  • Submicromolar levels of calcium control the balance of beating between the two flagella in demembranated models of Chlamydomonas.

    Ritsu Kamiya;George B. Witman

  • Isolation of Chlamydomonas flagella and flagellar axonemes.

    George B. Witman

  • The Chlamydomonas reinhardtii BBSome is an IFT cargo required for export of specific signaling proteins from flagella

    Karl-Ferdinand Lechtreck;Eric C. Johnson;Tsuyoshi Sakai;Deborah A. Cochran

  • Calcium control of waveform in isolated flagellar axonemes of chlamydomonas

    Matthew Bessen;Rose B. Fay;George B. Witman

  • Outer doublet heterogeneity reveals structural polarity related to beat direction in Chlamydomonas flagella.

    Harold J. Hoops;George B. Witman

  • Functional analysis of an individual IFT protein: IFT46 is required for transport of outer dynein arms into flagella

    Yuqing Hou;Hongmin Qin;John A. Follit;Gregory J. Pazour

  • Mutations in Hydin impair ciliary motility in mice

    Karl-Ferdinand Lechtreck;Philippe Delmotte;Michael L. Robinson;Michael J. Sanderson

  • Radial spoke proteins of Chlamydomonas flagella

    Pinfen Yang;Dennis R. Diener;Chun Yang;Takahiro Kohno

Frequent Co-Authors

Gregory J. Pazour
Gregory J. Pazour University of Massachusetts Chan Medical School
Stephen M. King
Stephen M. King University of Connecticut Health Center
Ritsu Kamiya
Ritsu Kamiya University of Tokyo
Joel L. Rosenbaum
Joel L. Rosenbaum Yale University
Mary E. Porter
Mary E. Porter University of Minnesota
Wallace F. Marshall
Wallace F. Marshall University of California, San Francisco
Joseph C. Besharse
Joseph C. Besharse Medical College of Wisconsin
Winfield S. Sale
Winfield S. Sale Emory University
Susan K. Dutcher
Susan K. Dutcher Washington University in St. Louis
Peter J. Scambler
Peter J. Scambler University College London

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