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Medicine

D-Index
93
Citations
31160
World Ranking
10906
National Ranking
5610

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Douglas E. Vaughan is affiliated with Northwestern University in the United States and has a research focus primarily within the field of Medicine. Their work spans several subfields including Molecular Biology, Hematology, Cardiology and Cardiovascular Medicine, Epidemiology, and Pediatrics, Perinatology and Child Health.

The scientist's research topics cover a wide range of biological and medical mechanisms. Key topics include:

  • Protease and Inhibitor Mechanisms
  • Liver Disease Diagnosis and Treatment
  • Epigenetics and DNA Methylation
  • Biomarkers in Disease Mechanisms
  • Blood Coagulation and Thrombosis Mechanisms
  • Diet, Metabolism, and Disease
  • Metabolism, Diabetes, and Cancer

Among recent publications associated with Douglas E. Vaughan are the following papers:

  • Role of PAI-1 in hepatic steatosis and dyslipidemia, 2021, Scientific Reports
  • Inequalities in urban greenness and epigenetic aging: Different associations by race and neighborhood socioeconomic status, 2023, Science Advances
  • Mid-life epigenetic age, neuroimaging brain age, and cognitive function: coronary artery risk development in young adults (CARDIA) study, 2022, Aging
  • Targeting of plasminogen activator inhibitor-1 activity promotes elimination of chronic myeloid leukemia stem cells, 2020, Haematologica
  • Identification of Cardiac Fibrosis in Young Adults With a Homozygous Frameshift Variant in SERPINE1, 2021, JAMA Cardiology

Douglas E. Vaughan has collaborated frequently with several co-authors, including:

  • Mesut Eren
  • Elizabeth Lux
  • Toshio Miyata
  • Lisa D. Wilsbacher
  • Saul Soberanes

Publications by this scientist appear repeatedly in a number of notable venues, including:

  • Circulation
  • Journal of Clinical Investigation
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Human Reproduction
  • Scientific Reports

Douglas E. Vaughan holds membership in the Association of American Physicians.

Best Publications

  • Effect of captopril on progressive ventricular dilatation after anterior myocardial infarction.

    Marc A. Pfeffer;Gervasio A. Lamas;Douglas E. Vaughan;Alfred F. Parisi

  • Angiotensin-Converting Enzyme Inhibitors

    Nancy J. Brown;Douglas E. Vaughan

  • Endogenous tissue-type plasminogen activator and risk of myocardial infarction

    P.M. Ridker;P.M. Ridker;D.E. Vaughan;D.E. Vaughan;Je Manson;Je Manson;Ch Hennekens;Ch Hennekens

  • Angiotensin II regulates the expression of plasminogen activator inhibitor-1 in cultured endothelial cells. A potential link between the renin-angiotensin system and thrombosis.

    Douglas E. Vaughan;Stergios A. Lazos;Kirk Tong

  • PAI-1 in tissue fibrosis

    Asish K. Ghosh;Douglas E. Vaughan

  • Established and Emerging Plasma Biomarkers in the Prediction of First Atherothrombotic Events

    Paul M Ridker;Nancy J. Brown;Douglas E. Vaughan;David G. Harrison

  • PAI-1 and atherothrombosis.

    Douglas E. Vaughan

  • Stimulation of plasminogen activator inhibitor in vivo by infusion of angiotensin II. Evidence of a potential interaction between the renin-angiotensin system and fibrinolytic function.

    Paul M. Ridker;Cynthia L. Gaboury;Paul R. Conlin;Ellen W. Seely

  • RANDOMISED CONTROLLED TRIAL OF RECOMBINANT TISSUE PLASMINOGEN ACTIVATOR VERSUS UROKINASE IN THE TREATMENT OF ACUTE PULMONARY EMBOLISM

    Samuel Z. Goldhaber;John Heit;G. V R K Sharma;J. Stevan Nagel

  • Prevention of Obesity and Insulin Resistance in Mice Lacking Plasminogen Activator Inhibitor 1

    Li Jun Ma;Su Li Mao;Kevin L. Taylor;Talerngsak Kanjanabuch

  • The relevance of tissue angiotensin-converting enzyme: Manifestations in mechanistic and endpoint data

    Victor J. Dzau;Kenneth Bernstein;David Celermajer;Jerome Cohen;Jerome Cohen

  • Effect of the Use and Timing of Bone Marrow Mononuclear Cell Delivery on Left Ventricular Function After Acute Myocardial Infarction: The TIME Randomized Trial

    Jay H. Traverse;Timothy D. Henry;Carl J. Pepine;James T. Willerson

  • Prospective study of endogenous tissue plasminogen activator and risk of stroke

    P.M. Ridker;C.H. Hennekens;J.E. Manson;D.E. Vaughan

  • Identification of Authentic Estrogen Receptor in Cultured Endothelial Cells A Potential Mechanism for Steroid Hormone Regulation of Endothelial Function

    Christo D. Venkov;Alan B. Rankin;Douglas E. Vaughan

  • Kruppel-Like Factor 2 (KLF2) Regulates Endothelial Thrombotic Function

    Zhiyong Lin;Ajay Kumar;Sucharita SenBanerjee;Kristine Staniszewski

  • Molecular and physiological manifestations and measurement of aging in humans.

    Sadiya S. Khan;Benjamin D. Singer;Douglas E. Vaughan

  • Angiotensin induction of PAI-1 expression in endothelial cells is mediated by the hexapeptide angiotensin IV.

    D M Kerins;Q Hao;D E Vaughan

  • Association of Moderate Alcohol Consumption and Plasma Concentration of Endogenous Tissue-Type Plasminogen Activator

    Paul M. Ridker;Douglas E. Vaughan;Meir J. Stampfer;Robert J. Glynn

  • Left ventricular remodeling in the year after first anterior myocardial infarction: a quantitative analysis of contractile segment lengths and ventricular shape.

    Gary F. Mitchell;Gervasio A. Lamas;Douglas E. Vaughan;Marc A. Pfeffer

  • Effect of Intracoronary Delivery of Autologous Bone Marrow Mononuclear Cells 2 to 3 Weeks Following Acute Myocardial Infarction on Left Ventricular Function The LateTIME Randomized Trial

    Jay H. Traverse;Timothy D. Henry;Stephen G. Ellis;Carl J. Pepine

Frequent Co-Authors

Nancy J. Brown
Nancy J. Brown Vanderbilt University Medical Center
Joseph Loscalzo
Joseph Loscalzo Harvard Medical School
Toshio Miyata
Toshio Miyata Tohoku University
Paul M. Ridker
Paul M. Ridker Brigham and Women's Hospital
Marc A. Pfeffer
Marc A. Pfeffer Harvard Medical School
Agnes B. Fogo
Agnes B. Fogo Vanderbilt University Medical Center
Douglas W. Losordo
Douglas W. Losordo Northwestern University
Jason H. Moore
Jason H. Moore University of Pennsylvania
Eugene Braunwald
Eugene Braunwald Harvard Medical School
Sanjiv J. Shah
Sanjiv J. Shah Northwestern University

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