Member of the Association of American Physicians
His scientific interests lie mostly in Internal medicine, Endocrinology, Plasminogen activator, Plasminogen activator inhibitor-1 and Myocardial infarction. His Internal medicine research focuses on Cardiology and how it relates to ACE inhibitor. The various areas that Douglas E. Vaughan examines in his Endocrinology study include Bradykinin and Enzyme inhibitor.
He works mostly in the field of Plasminogen activator, limiting it down to topics relating to Plasmin and, in certain cases, Angiotensin Receptor Antagonists, as a part of the same area of interest. His research integrates issues of Insulin resistance, Luciferase, Fibrinolysis, Rasm and Sp1 transcription factor in his study of Plasminogen activator inhibitor-1. His studies examine the connections between Myocardial infarction and genetics, as well as such issues in Risk factor, with regards to Disease, Cohort, Statistical significance, Relative risk and Endogeny.
Douglas E. Vaughan focuses on Internal medicine, Endocrinology, Plasminogen activator, Plasminogen activator inhibitor-1 and Fibrinolysis. Much of his study explores Internal medicine relationship to Cardiology. His research in Endocrinology tackles topics such as Bradykinin which are related to areas like Vasodilation and Sodium nitroprusside.
His Plasminogen activator research incorporates themes from Plasmin, Tissue plasminogen activator, Biochemistry, Fibrosis and In vivo. His Plasminogen activator inhibitor-1 research focuses on subjects like Molecular biology, which are linked to Gene expression. His Myocardial infarction research is multidisciplinary, incorporating elements of Stroke volume and Heart failure.
His main research concerns Internal medicine, Plasminogen activator, Plasminogen activator inhibitor-1, Endocrinology and Cancer research. Internal medicine is closely attributed to Cardiology in his research. His Plasminogen activator research integrates issues from Senescence, Cell biology, Tissue homeostasis, Urine and Induced pluripotent stem cell.
His work deals with themes such as Nonalcoholic fatty liver disease, Metabolic syndrome, Allele and Pathogenesis, which intersect with Plasminogen activator inhibitor-1. Douglas E. Vaughan works mostly in the field of Endocrinology, limiting it down to concerns involving Antagonist and, occasionally, Triglyceride. His Cancer research study integrates concerns from other disciplines, such as Immunology, Gene mutation and Fibrosis, Pulmonary fibrosis, Cardiac fibrosis.
His primary areas of investigation include Senescence, Cancer research, Cardiac fibrosis, Plasminogen activator inhibitor-1 and Fibrosis. His research on Cancer research also deals with topics like
The concepts of his Fibrosis study are interwoven with issues in Angiotensin II, Extracellular matrix and Epigenetics. Douglas E. Vaughan is researching Circadian rhythm as part of the investigation of Endocrinology and Internal medicine. Douglas E. Vaughan works in the field of Internal medicine, namely Urokinase.
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Effect of captopril on progressive ventricular dilatation after anterior myocardial infarction.
Marc A. Pfeffer;Gervasio A. Lamas;Douglas E. Vaughan;Alfred F. Parisi.
The New England Journal of Medicine (1988)
Angiotensin-Converting Enzyme Inhibitors
Nancy J. Brown;Douglas E. Vaughan.
Circulation (1998)
Endogenous tissue-type plasminogen activator and risk of myocardial infarction
P.M. Ridker;P.M. Ridker;D.E. Vaughan;D.E. Vaughan;Je Manson;Je Manson;Ch Hennekens;Ch Hennekens.
The Lancet (1993)
Angiotensin II regulates the expression of plasminogen activator inhibitor-1 in cultured endothelial cells. A potential link between the renin-angiotensin system and thrombosis.
Douglas E. Vaughan;Stergios A. Lazos;Kirk Tong.
Journal of Clinical Investigation (1995)
Established and Emerging Plasma Biomarkers in the Prediction of First Atherothrombotic Events
Paul M Ridker;Nancy J. Brown;Douglas E. Vaughan;David G. Harrison.
Circulation (2004)
Stimulation of plasminogen activator inhibitor in vivo by infusion of angiotensin II. Evidence of a potential interaction between the renin-angiotensin system and fibrinolytic function.
Paul M. Ridker;Cynthia L. Gaboury;Paul R. Conlin;Ellen W. Seely.
Circulation (1993)
RANDOMISED CONTROLLED TRIAL OF RECOMBINANT TISSUE PLASMINOGEN ACTIVATOR VERSUS UROKINASE IN THE TREATMENT OF ACUTE PULMONARY EMBOLISM
Samuel Z. Goldhaber;John Heit;G. V R K Sharma;J. Stevan Nagel.
The Lancet (1988)
PAI-1 in tissue fibrosis
Asish K. Ghosh;Douglas E. Vaughan.
Journal of Cellular Physiology (2012)
PAI-1 and atherothrombosis.
Douglas E. Vaughan.
Journal of Thrombosis and Haemostasis (2005)
The relevance of tissue angiotensin-converting enzyme: Manifestations in mechanistic and endpoint data
Victor J. Dzau;Kenneth Bernstein;David Celermajer;Jerome Cohen;Jerome Cohen.
American Journal of Cardiology (2001)
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