D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 84 Citations 27,195 247 World Ranking 7846 National Ranking 4277

Research.com Recognitions

Awards & Achievements

Member of the Association of American Physicians

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Gene
  • Enzyme

His scientific interests lie mostly in Internal medicine, Endocrinology, Plasminogen activator, Plasminogen activator inhibitor-1 and Myocardial infarction. His Internal medicine research focuses on Cardiology and how it relates to ACE inhibitor. The various areas that Douglas E. Vaughan examines in his Endocrinology study include Bradykinin and Enzyme inhibitor.

He works mostly in the field of Plasminogen activator, limiting it down to topics relating to Plasmin and, in certain cases, Angiotensin Receptor Antagonists, as a part of the same area of interest. His research integrates issues of Insulin resistance, Luciferase, Fibrinolysis, Rasm and Sp1 transcription factor in his study of Plasminogen activator inhibitor-1. His studies examine the connections between Myocardial infarction and genetics, as well as such issues in Risk factor, with regards to Disease, Cohort, Statistical significance, Relative risk and Endogeny.

His most cited work include:

  • Effect of captopril on progressive ventricular dilatation after anterior myocardial infarction. (1003 citations)
  • Angiotensin-Converting Enzyme Inhibitors (697 citations)
  • Endogenous tissue-type plasminogen activator and risk of myocardial infarction (551 citations)

What are the main themes of his work throughout his whole career to date?

Douglas E. Vaughan focuses on Internal medicine, Endocrinology, Plasminogen activator, Plasminogen activator inhibitor-1 and Fibrinolysis. Much of his study explores Internal medicine relationship to Cardiology. His research in Endocrinology tackles topics such as Bradykinin which are related to areas like Vasodilation and Sodium nitroprusside.

His Plasminogen activator research incorporates themes from Plasmin, Tissue plasminogen activator, Biochemistry, Fibrosis and In vivo. His Plasminogen activator inhibitor-1 research focuses on subjects like Molecular biology, which are linked to Gene expression. His Myocardial infarction research is multidisciplinary, incorporating elements of Stroke volume and Heart failure.

He most often published in these fields:

  • Internal medicine (66.37%)
  • Endocrinology (50.15%)
  • Plasminogen activator (39.82%)

What were the highlights of his more recent work (between 2014-2021)?

  • Internal medicine (66.37%)
  • Plasminogen activator (39.82%)
  • Plasminogen activator inhibitor-1 (30.97%)

In recent papers he was focusing on the following fields of study:

His main research concerns Internal medicine, Plasminogen activator, Plasminogen activator inhibitor-1, Endocrinology and Cancer research. Internal medicine is closely attributed to Cardiology in his research. His Plasminogen activator research integrates issues from Senescence, Cell biology, Tissue homeostasis, Urine and Induced pluripotent stem cell.

His work deals with themes such as Nonalcoholic fatty liver disease, Metabolic syndrome, Allele and Pathogenesis, which intersect with Plasminogen activator inhibitor-1. Douglas E. Vaughan works mostly in the field of Endocrinology, limiting it down to concerns involving Antagonist and, occasionally, Triglyceride. His Cancer research study integrates concerns from other disciplines, such as Immunology, Gene mutation and Fibrosis, Pulmonary fibrosis, Cardiac fibrosis.

Between 2014 and 2021, his most popular works were:

  • MiR-125b Is Critical for Fibroblast-to-Myofibroblast Transition and Cardiac Fibrosis. (117 citations)
  • Molecular and physiological manifestations and measurement of aging in humans. (116 citations)
  • Plasminogen Activator Inhibitor-1 Is a Marker and a Mediator of Senescence. (75 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • Enzyme

His primary areas of investigation include Senescence, Cancer research, Cardiac fibrosis, Plasminogen activator inhibitor-1 and Fibrosis. His research on Cancer research also deals with topics like

  • microRNA, Myofibroblast, Wound healing, Tissue homeostasis and Matrix metalloproteinase most often made with reference to Fibroblast,
  • Pathology and related In vivo, Pharmacology, Multiple sclerosis, Encephalomyelitis and Fingolimod. His Plasminogen activator inhibitor-1 research is classified as research in Plasminogen activator.

The concepts of his Fibrosis study are interwoven with issues in Angiotensin II, Extracellular matrix and Epigenetics. Douglas E. Vaughan is researching Circadian rhythm as part of the investigation of Endocrinology and Internal medicine. Douglas E. Vaughan works in the field of Internal medicine, namely Urokinase.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Effect of captopril on progressive ventricular dilatation after anterior myocardial infarction.

Marc A. Pfeffer;Gervasio A. Lamas;Douglas E. Vaughan;Alfred F. Parisi.
The New England Journal of Medicine (1988)

1326 Citations

Angiotensin-Converting Enzyme Inhibitors

Nancy J. Brown;Douglas E. Vaughan.
Circulation (1998)

933 Citations

Endogenous tissue-type plasminogen activator and risk of myocardial infarction

P.M. Ridker;P.M. Ridker;D.E. Vaughan;D.E. Vaughan;Je Manson;Je Manson;Ch Hennekens;Ch Hennekens.
The Lancet (1993)

743 Citations

Angiotensin II regulates the expression of plasminogen activator inhibitor-1 in cultured endothelial cells. A potential link between the renin-angiotensin system and thrombosis.

Douglas E. Vaughan;Stergios A. Lazos;Kirk Tong.
Journal of Clinical Investigation (1995)

695 Citations

Established and Emerging Plasma Biomarkers in the Prediction of First Atherothrombotic Events

Paul M Ridker;Nancy J. Brown;Douglas E. Vaughan;David G. Harrison.
Circulation (2004)

586 Citations

Stimulation of plasminogen activator inhibitor in vivo by infusion of angiotensin II. Evidence of a potential interaction between the renin-angiotensin system and fibrinolytic function.

Paul M. Ridker;Cynthia L. Gaboury;Paul R. Conlin;Ellen W. Seely.
Circulation (1993)

567 Citations

RANDOMISED CONTROLLED TRIAL OF RECOMBINANT TISSUE PLASMINOGEN ACTIVATOR VERSUS UROKINASE IN THE TREATMENT OF ACUTE PULMONARY EMBOLISM

Samuel Z. Goldhaber;John Heit;G. V R K Sharma;J. Stevan Nagel.
The Lancet (1988)

492 Citations

PAI-1 in tissue fibrosis

Asish K. Ghosh;Douglas E. Vaughan.
Journal of Cellular Physiology (2012)

485 Citations

PAI-1 and atherothrombosis.

Douglas E. Vaughan.
Journal of Thrombosis and Haemostasis (2005)

482 Citations

The relevance of tissue angiotensin-converting enzyme: Manifestations in mechanistic and endpoint data

Victor J. Dzau;Kenneth Bernstein;David Celermajer;Jerome Cohen;Jerome Cohen.
American Journal of Cardiology (2001)

475 Citations

If you think any of the details on this page are incorrect, let us know.

Contact us

Best Scientists Citing Douglas E. Vaughan

Marc A. Pfeffer

Marc A. Pfeffer

Brigham and Women's Hospital

Publications: 64

Paul Declerck

Paul Declerck

KU Leuven

Publications: 61

Nancy J. Brown

Nancy J. Brown

Vanderbilt University Medical Center

Publications: 59

Samuel Z. Goldhaber

Samuel Z. Goldhaber

Brigham and Women's Hospital

Publications: 45

Agnes B. Fogo

Agnes B. Fogo

Vanderbilt University Medical Center

Publications: 43

Joseph Loscalzo

Joseph Loscalzo

Brigham and Women's Hospital

Publications: 40

Mukesh K. Jain

Mukesh K. Jain

Jawaharlal Nehru University

Publications: 39

Jason H. Moore

Jason H. Moore

University of Pennsylvania

Publications: 39

Paul M. Ridker

Paul M. Ridker

Harvard Medical School

Publications: 38

Gervasio A. Lamas

Gervasio A. Lamas

Columbia University

Publications: 36

Gregory Y.H. Lip

Gregory Y.H. Lip

University of Liverpool

Publications: 34

Bertram Pitt

Bertram Pitt

University of Michigan–Ann Arbor

Publications: 33

David E. Newby

David E. Newby

University of Edinburgh

Publications: 32

Alvin H. Schmaier

Alvin H. Schmaier

University Hospitals of Cleveland

Publications: 32

Joshua M. Hare

Joshua M. Hare

University of Miami

Publications: 30

Irène Juhan-Vague

Irène Juhan-Vague

Inserm : Institut national de la santé et de la recherche médicale

Publications: 30

Trending Scientists

Miska Hannuksela

Miska Hannuksela

Nokia (Finland)

Alessandro Ferrero

Alessandro Ferrero

Polytechnic University of Milan

Sachiko Tsukamoto

Sachiko Tsukamoto

Kumamoto University

Joel K. W. Yang

Joel K. W. Yang

Singapore University of Technology and Design

Judith S. Eisen

Judith S. Eisen

University of Oregon

John P. Carr

John P. Carr

University of Cambridge

Esther Schelling

Esther Schelling

University of Basel

Tatsuo Miyamura

Tatsuo Miyamura

National Institutes of Health

Simon Wallis

Simon Wallis

University of Tokyo

Peachie Moore

Peachie Moore

University of Pennsylvania

David L. Sacks

David L. Sacks

National Institutes of Health

David Bunce

David Bunce

University of Leeds

Alastair M. Thompson

Alastair M. Thompson

Baylor College of Medicine

Alan Petersen

Alan Petersen

Monash University

Karen Swan

Karen Swan

University of Illinois at Springfield

Takaharu Otsuka

Takaharu Otsuka

University of Tokyo

Something went wrong. Please try again later.