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Medicine

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206
Citations
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World Ranking
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Research.com Recognitions

  • 2026 - Research.com Medicine in United States Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Medicine in United States Leader Award
  • 2023 - Research.com Medicine in United States Leader Award
  • 2017 - Distinguished Fellowship Award, American College of Cardiology (ACC)
  • 2015 - Distinguished Scientist Award, American Heart Association
  • 2013 - James B. Herrick Award for Outstanding Achievement in Clinical Cardiology, American Heart Association
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Marc A. Pfeffer is affiliated with Harvard Medical School in the United States and has a substantial body of research within the field of Medicine, with a particular emphasis on Cardiology and Cardiovascular Medicine. Their scholarly contributions span over 400 publications, predominantly focusing on heart failure treatment and management as well as cardiovascular function and risk factors.

The main fields covered in their research include:

  • Medicine

More specifically, their work advances knowledge in several subfields, including:

  • Cardiology and Cardiovascular Medicine
  • Endocrinology, Diabetes and Metabolism
  • Pulmonary and Respiratory Medicine
  • Surgery
  • Statistics and Probability

Among the primary topics addressed in Pfeffer's research are:

  • Heart Failure Treatment and Management
  • Cardiovascular Function and Risk Factors
  • Diabetes Treatment and Management
  • Potassium and Related Disorders
  • Cardiac pacing and defibrillation studies
  • Blood Pressure and Hypertension Studies
  • Hormonal Regulation and Hypertension

Frequent publication venues for Pfeffer's work include:

  • Journal of the American College of Cardiology
  • European Journal of Heart Failure
  • Circulation
  • JACC Heart Failure
  • European Heart Journal

Pfeffer has collaborated extensively with several notable coauthors, such as:

  • John J.V. McMurray
  • Scott D. Solomon
  • Brian Claggett
  • Akshay S. Desai
  • Michael R. Zile

Some significant recent papers authored or coauthored by Marc A. Pfeffer include:

  • Renin-Angiotensin-Aldosterone System Inhibitors in Patients with Covid-19, 2020, New England Journal of Medicine
  • Effect of statin therapy on muscle symptoms: an individual participant data meta-analysis of large-scale, randomised, double-blind trials, 2022, The Lancet
  • Angiotensin-Neprilysin Inhibition and Renal Outcomes in Heart Failure With Preserved Ejection Fraction, 2020, Circulation
  • Sacubitril-valsartan as a treatment for apparent resistant hypertension in patients with heart failure and preserved ejection fraction, 2021, European Heart Journal
  • Prospective ARNI vs. ACE inhibitor trial to DetermIne Superiority in reducing heart failure Events after Myocardial Infarction (PARADISE-MI): design and baseline characteristics, 2021, European Journal of Heart Failure

Marc A. Pfeffer has been recognized with multiple awards throughout their career, including:

  • Distinguished Fellowship Award, American College of Cardiology (ACC), 2017
  • Distinguished Scientist Award, American Heart Association, 2015
  • James B. Herrick Award for Outstanding Achievement in Clinical Cardiology, American Heart Association, 2013
  • Member of the Association of American Physicians

Best Publications

  • The Effect of Pravastatin on Coronary Events after Myocardial Infarction in Patients with Average Cholesterol Levels

    F. M. Sacks;M. A. Pfeffer;L. A. Moye;J. L. Rouleau

  • EFFECT OF CAPTOPRIL ON MORTALITY AND MORBIDITY IN PATIENTS WITH LEFT VENTRICULAR DYSFUNCTION AFTER MYOCARDIAL INFARCTION. RESULTS OF THE SURVIVAL AND VENTRICULAR ENLARGEMENT TRIAL

    Marc A. Pfeffer;Eugene Braunwald;Lemuel A. Moyé;Lofty Basta

  • Kidney disease as a risk factor for development of cardiovascular disease: a statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention.

    Mark J. Sarnak;Andrew S. Levey;Anton C. Schoolwerth;Josef Coresh

  • Intensive versus moderate lipid lowering with statins after acute coronary syndromes.

    Christopher P. Cannon;Eugene Braunwald;Carolyn H. McCabe;Daniel J. Rader

  • Ventricular remodeling after myocardial infarction. Experimental observations and clinical implications.

    Marc A. Pfeffer;Eugene Braunwald

  • Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function intolerant to angiotensin-converting-enzyme inhibitors: the CHARM-Alternative trial

    Christopher B Granger;John J V McMurray;Salim Yusuf;Peter Held

  • Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: the CHARM-Preserved Trial

    Salim Yusuf;Marc A Pfeffer;Karl Swedberg;Christopher B Granger

  • AHA/ACC Guidelines for Secondary Prevention for Patients With Coronary and Other Atherosclerotic Vascular Disease: 2006 Update Endorsed by the National Heart, Lung, and Blood Institute

    Sidney C. Smith Jr.;Jerilyn Allen;Steven N. Blair;Robert O. Bonow

  • Valsartan, Captopril, or Both in Myocardial Infarction Complicated by Heart Failure, Left Ventricular Dysfunction, or Both

    Marc A. Pfeffer;John J.V. McMurray;Eric J. Velazquez;Jean-Lucien Rouleau

  • Effect of clopidogrel added to aspirin in patients with atrial fibrillation.

    Stuart J. Connolly;Janice Pogue;Robert G. Hart;Stefan H. Hohnloser

  • Clopidogrel plus aspirin versus oral anticoagulation for atrial fibrillation in the Atrial fibrillation Clopidogrel Trial with Irbesartan for prevention of Vascular Events (ACTIVE W): a randomised controlled trial.

    S Connolly;J Pogue;R Hart

  • Spironolactone for Heart Failure with Preserved Ejection Fraction

    Bertram Pitt;Marc A. Pfeffer;Susan F. Assmann;Robin Boineau

  • C-Reactive Protein Levels and Outcomes after Statin Therapy

    Paul M Ridker;Christopher P. Cannon;David Morrow;Nader Rifai

  • Cardiovascular Risk Associated With Celecoxib in a Clinical Trial for Colorectal Adenoma Prevention

    Scott D. Solomon;John J.V. McMurray;Marc A. Pfeffer;Janet Wittes

  • Effects of candesartan on mortality and morbidity in patients with chronic heart failure: the CHARM-Overall programme

    Marc A Pfeffer;Karl Swedberg;Christopher B Granger;Peter Held

  • Relation between renal dysfunction and cardiovascular outcomes after myocardial infarction.

    Nagesh S Anavekar;John J V McMurray;Eric J Velazquez;Scott D Solomon

  • Lixisenatide in Patients with Type 2 Diabetes and Acute Coronary Syndrome

    Marc A. Pfeffer;Brian L. Claggett;Rafael Diaz;Kenneth Dickstein

  • A Trial of Darbepoetin Alfa in Type 2 Diabetes and Chronic Kidney Disease

    Marc A Pfeffer;Emmanuel A. Burdmann;Chao Yin Chen;Mark E. Cooper

  • Renin-Angiotensin-Aldosterone System Inhibitors in Patients with Covid-19.

    Muthiah Vaduganathan;Orly Vardeny;Thomas Michel;John J.V. McMurray

  • Long-Term Effects of Pravastatin on Plasma Concentration of C-reactive Protein

    Paul M. Ridker;Nader Rifai;Marc A. Pfeffer;Frank Sacks

Frequent Co-Authors

Scott D. Solomon
Scott D. Solomon Brigham and Women's Hospital
John J.V. McMurray
John J.V. McMurray University of Glasgow
Karl Swedberg
Karl Swedberg University of Gothenburg
Brian Claggett
Brian Claggett Brigham and Women's Hospital
Eugene Braunwald
Eugene Braunwald Harvard Medical School
Eldrin F. Lewis
Eldrin F. Lewis Stanford University
Akshay S. Desai
Akshay S. Desai Brigham and Women's Hospital
Aldo P. Maggioni
Aldo P. Maggioni Heart Care Foundation, ANMCO Research Center, Florence
Lars Køber
Lars Køber Copenhagen University Hospital
Eric J. Velazquez
Eric J. Velazquez Yale University

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