World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
117
Citations
54841
World Ranking
363
National Ranking
231

Medicine

D-Index
119
Citations
56812
World Ranking
3870
National Ranking
2116

Research.com Recognitions

  • 2018 - Member of the National Academy of Sciences
  • 1996 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1985 - Oswald Avery Award, Infectious Diseases Society of America

Overview

Dennis L. Kasper is affiliated with Harvard University in the United States. Their research spans several interrelated fields, primarily within biochemistry, genetics, molecular biology, medicine, and immunology and microbiology.

Their work focuses extensively on gut microbiota and health, immune cell function and interaction, and infectious diseases. Key scientific topics include:

  • Gut microbiota and health
  • Immune Cell Function and Interaction
  • Clostridium difficile and Clostridium perfringens research
  • Probiotics and Fermented Foods
  • IL-33, ST2, and ILC Pathways
  • Helicobacter pylori-related gastroenterology studies
  • Infant Nutrition and Health

Their research has been published in various prominent venues. Frequent publication journals include:

  • Nature
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell
  • Cell Host & Microbe
  • SSRN Electronic Journal

Dennis L. Kasper has collaborated regularly with several scientists, including:

  • Meng Wu
  • Xinyang Song
  • Francesca S. Gazzaniga
  • Wenfeng Zheng
  • Ji-Sun Yoo

Recent publications featuring their research include the following notable papers:

  • "Commensal Microbiota Modulation of Natural Resistance to Virus Infection," 2020, Cell
  • "Transcriptional and proteomic insights into the host response in fatal COVID-19 cases," 2020, Proceedings of the National Academy of Sciences
  • "An Immunologic Mode of Multigenerational Transmission Governs a Gut Treg Setpoint," 2020, Cell
  • "Bile acids modified by the intestinal microbiota promote colorectal cancer growth by suppressing CD8+ T cell effector functions," 2024, Immunity
  • "Targeting PD-L2-RGMb overcomes microbiome-related immunotherapy resistance," 2023, Nature

Award recognition in their career includes:

  • Member of the National Academy of Sciences, 2018
  • Fellow of the American Association for the Advancement of Science (AAAS), 1996
  • Oswald Avery Award, Infectious Diseases Society of America, 1985

Best Publications

  • An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system.

    Sarkis K. Mazmanian;Sarkis K. Mazmanian;Cui Hua Liu;Cui Hua Liu;Arthur O. Tzianabos;Arthur O. Tzianabos;Dennis L. Kasper;Dennis L. Kasper

  • Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae: Implications for the microbial “pan-genome”

    Hervé Tettelin;Vega Masignani;Michael J. Cieslewicz;Claudio Donati

  • A microbial symbiosis factor prevents intestinal inflammatory disease

    Sarkis K. Mazmanian;June L. Round;Dennis L. Kasper;Dennis L. Kasper

  • How colonization by microbiota in early life shapes the immune system

    Thomas Gensollen;Shankar S. Iyer;Dennis L. Kasper;Richard S. Blumberg

  • Microbial Exposure During Early Life Has Persistent Effects on Natural Killer T Cell Function

    Torsten Olszak;Dingding An;Sebastian Zeissig;Miguel Pinilla Vera

  • Gut Immune Maturation Depends on Colonization with a Host-Specific Microbiota

    Hachung Chung;Hachung Chung;Sünje Johanna Pamp;Sünje Johanna Pamp;Jonathan A. Hill;Neeraj K. Surana;Neeraj K. Surana;Neeraj K. Surana

  • Microbial bile acid metabolites modulate gut RORγ+ regulatory T cell homeostasis.

    Xinyang Song;Ximei Sun;Sungwhan F. Oh;Sungwhan F. Oh;Meng Wu

  • Individual intestinal symbionts induce a distinct population of RORγ+ regulatory T cells

    Esen Sefik;Naama Geva-Zatorsky;Sungwhan Oh;Liza Konnikova

  • Correlation of Maternal Antibody Deficiency with Susceptibility to Neonatal Group B Streptococcal Infection

    Carol J. Baker;Dennis L. Kasper

  • Mining the Human Gut Microbiota for Immunomodulatory Organisms

    Naama Geva-Zatorsky;Esen Sefik;Lindsay Kua;Lesley Pasman

  • A Complex Human-Gut Microbiome Cultured in an Anaerobic Intestine-on-a-Chip

    Sasan Jalili-Firoozinezhad;Sasan Jalili-Firoozinezhad;Francesca S. Gazzaniga;Francesca S. Gazzaniga;Elizabeth L. Calamari;Diogo M. Camacho

  • Identification of a universal Group B streptococcus vaccine by multiple genome screen.

    Domenico Maione;Immaculada Margarit;Cira D. Rinaudo;Vega Masignani

  • Sphingolipids from a Symbiotic Microbe Regulate Homeostasis of Host Intestinal Natural Killer T Cells

    Dingding An;Sungwhan F. Oh;Torsten Olszak;Joana F. Neves

  • Clindamycin-Associated Colitis Due to a Toxin-Producing Species of Clostridium in Hamsters

    John G. Bartlett;Andrew B. Onderdonk;Ronald L. Cisneros;Dennis L. Kasper

  • A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance

    Cholsoon Jang;Sungwhan F Oh;Shogo Wada;Glenn C Rowe

  • Complete genome sequence and comparative genomic analysis of an emerging human pathogen, serotype V Streptococcus agalactiae

    Hervé Tettelin;Vega Masignani;Michael J. Cieslewicz;Jonathan A. Eisen;Jonathan A. Eisen

  • Immunologic Response of Man to Group B Meningococcal Polysaccharide Vaccines

    F. A. Wyle;M. S. Artenstein;B. L. Brandt;E. C. Tramont

  • A polysaccharide from the human commensal Bacteroides fragilis protects against CNS demyelinating disease

    J Ochoa-Repáraz;D W Mielcarz;Y Wang;S Begum-Haque

  • The love-hate relationship between bacterial polysaccharides and the host immune system.

    Sarkis K. Mazmanian;Dennis L. Kasper

  • Immunization of Pregnant Women with a Polysaccharide Vaccine of Group B Streptococcus

    Carol J. Baker;Marcia A. Rench;Morven S. Edwards;Robert J. Carpenter

  • Harrison, principios de medicina interna

    J. Larry Jameson;Anthony S. Fauci;Dennis L. Kasper;Stephen L. Hauser

Frequent Co-Authors

Andrew B. Onderdonk
Andrew B. Onderdonk Brigham and Women's Hospital
Carol J. Baker
Carol J. Baker Baylor College of Medicine
Harold J. Jennings
Harold J. Jennings National Academies of Sciences, Engineering, and Medicine
Lawrence C. Madoff
Lawrence C. Madoff Massachusetts Department of Public Health
Frederick M. Ausubel
Frederick M. Ausubel Harvard University
Morven S. Edwards
Morven S. Edwards Baylor College of Medicine
Robert W. Finberg
Robert W. Finberg University of Massachusetts Chan Medical School
John G. Bartlett
John G. Bartlett Johns Hopkins University School of Medicine
Dan L. Longo
Dan L. Longo Harvard University
Eugene Braunwald
Eugene Braunwald Harvard Medical School

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