World's Best Scientists 2026 revealed!
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Immunology
UK
2026

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Best Scientists

D-Index
165
Citations
95403
World Ranking
1050
National Ranking
104

Immunology

D-Index
170
Citations
96589
World Ranking
56
National Ranking
3

Research.com Recognitions

  • 2026 - Research.com Immunology in United Kingdom Leader Award
  • 2025 - Research.com Immunology in United Kingdom Leader Award
  • 2022 - Research.com Immunology in United Kingdom Leader Award
  • 2019 - Robert Koch Prize
  • 2019 - Member of Academia Europaea
  • 2017 - Fellow of the American Academy of Arts and Sciences
  • 2016 - Fellow of the Royal Society, United Kingdom
  • 2005 - Member of the National Academy of Sciences

Overview

Rino Rappuoli is affiliated with Imperial College London in the United Kingdom. Their research primarily spans the field of Medicine, with significant contributions to several related subfields including Infectious Diseases, Epidemiology, Immunology, Microbiology, and Molecular Biology.

The scientist's work focuses on key topics such as SARS-CoV-2 and COVID-19 research, bacterial infections and vaccines, pneumonia and respiratory infections, viral gastroenteritis research and epidemiology, COVID-19 clinical research studies, immunotherapy and immune responses, and Escherichia coli research studies.

Among frequent coauthors are:

  • Emanuele Andreano
  • Mariagrazia Pizza
  • Ida Paciello
  • Claudia Sala
  • Simone Pecetta

Rappuoli's research outputs appear regularly in several publication venues, including:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • Science Translational Medicine
  • Human Vaccines & Immunotherapeutics

Recent papers include:

  • "The role of vaccines in combatting antimicrobial resistance," 2021, Nature Reviews Microbiology
  • "SARS-CoV-2 escape from a highly neutralizing COVID-19 convalescent plasma," 2021, Proceedings of the National Academy of Sciences
  • "Adjuvanting a subunit COVID-19 vaccine to induce protective immunity," 2021, Nature
  • "SARS-CoV-2 escapein vitro from a highly neutralizing COVID-19 convalescent plasma," 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • "Extremely potent human monoclonal antibodies from COVID-19 convalescent patients," 2021, Cell

They have also contributed to book publications with titles including:

  • "Three Dimensional Human Organotypic Models for Biomedical Research" (Springer Science+Business Media, 2021)
  • "Vaccines in the Global Era" (WORLD SCIENTIFIC (EUROPE) eBooks, 2021)
  • "Le coronavirus et ces microbes qu'il nous faut combattre, première édition" (Frontiers Media, 2022)

Rino Rappuoli has received several awards during their career, such as:

  • Member of Academia Europaea, 2019
  • Robert Koch Prize, 2019
  • Fellow of the American Academy of Arts and Sciences, 2017
  • Fellow of the Royal Society, United Kingdom, 2016
  • Member of the National Academy of Sciences, 2005

Best Publications

  • Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae: Implications for the microbial “pan-genome”

    Hervé Tettelin;Vega Masignani;Michael J. Cieslewicz;Claudio Donati

  • cag, a pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors.

    Stefano Censini;Christina Lange;Zhaoying Xiang;Jean E. Crabtree

  • Identification of vaccine candidates against serogroup B meningococcus by whole-genome sequencing.

    M Pizza;[No Value] Scarlato;[No Value] Masignani;MM Giuliani

  • The microbial pan-genome

    Duccio Medini;Claudio Donati;Hervé Tettelin;Vega Masignani

  • Helicobacter pylori virulence and genetic geography.

    Antonello Covacci;John L. Telford;Giuseppe Del Giudice;Julie Parsonnet

  • Complete Genome Sequence of Neisseria meningitidis Serogroup B Strain MC58

    Hervé Tettelin;Nigel J. Saunders;John Heidelberg;Alex C. Jeffries

  • An efficient method to make human monoclonal antibodies from memory B cells: potent neutralization of SARS coronavirus

    Elisabetta Traggiai;Stephan Becker;Kanta Subbarao;Larissa Kolesnikova

  • A universal vaccine for serogroup B meningococcus

    Marzia M. Giuliani;Jeannette Adu-Bobie;Maurizio Comanducci;Beatrice Aricò

  • ANALYSIS OF EXPRESSION OF CAGA AND VACA VIRULENCE FACTORS IN 43 STRAINS OF HELICOBACTER PYLORI REVEALS THAT CLINICAL ISOLATES CAN BE DIVIDED INTO TWO MAJOR TYPES AND THAT CAGA IS NOT NECESSARY FOR EXPRESSION OF THE VACUOLATING CYTOTOXIN

    Zhaoying Xiang;Stefano Censini;Pietro F. Bayeli;John L. Telford

  • Tyrosine phosphorylation of the Helicobacter pylori CagA antigen after cag-driven host cell translocation

    Markus Stein;Rino Rappuoli;Antonello Covacci

  • Development of a mouse model of Helicobacter pylori infection that mimics human disease.

    Marta Marchetti;Beatrice Aricò;Daniela Burroni;Natale Figura

  • Nonviral delivery of self-amplifying RNA vaccines

    Andrew J. Geall;Ayush Verma;Gillis R. Otten;Christine A. Shaw

  • Coxsackie B4 virus infection of β cells and natural killer cell insulitis in recent-onset type 1 diabetic patients

    Francesco Dotta;Stefano Censini;Astrid G. S. van Halteren;Lorella Marselli

  • Living dangerously: how Helicobacter pylori survives in the human stomach

    Cesare Montecucco;Rino Rappuoli

  • Correlates of adjuvanticity: A review on adjuvants in licensed vaccines.

    Giuseppe Del Giudice;Rino Rappuoli;Arnaud M. Didierlaurent

  • Reverse Vaccinology: Developing Vaccines in the Era of Genomics

    Alessandro Sette;Rino Rappuoli

  • Identification of a universal Group B streptococcus vaccine by multiple genome screen.

    Domenico Maione;Immaculada Margarit;Cira D. Rinaudo;Vega Masignani

  • SARS — beginning to understand a new virus

    Konrad Stadler;Vega Masignani;Markus Eickmann;Stephan Becker

  • Reverse vaccinology, a genome-based approach to vaccine development.

    Rino Rappuoli

  • Pili in Gram-positive pathogens

    John L. Telford;Michèle A. Barocchi;Immaculada Margarit;Rino Rappuoli

  • Reverse vaccinology : Genomics

    Rino Rappuoli

Frequent Co-Authors

Mariagrazia Pizza
Mariagrazia Pizza Imperial College London
Marzia Monica Giuliani
Marzia Monica Giuliani GlaxoSmithKline (Italy)
Cesare Montecucco
Cesare Montecucco University of Padua
Giuseppe Del Giudice
Giuseppe Del Giudice GlaxoSmithKline (United Kingdom)
Guido Grandi
Guido Grandi University of Trento
Antonello Covacci
Antonello Covacci Novartis (Switzerland)
John L. Telford
John L. Telford GlaxoSmithKline (Italy)
Emanuele Papini
Emanuele Papini University of Padua
Hervé Tettelin
Hervé Tettelin University of Maryland, Baltimore
Maurizio Comanducci
Maurizio Comanducci Novartis (Switzerland)

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