D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics and Molecular Biology D-index 90 Citations 21,865 153 World Ranking 650 National Ranking 35

Research.com Recognitions

Awards & Achievements

2012 - Grand prix de l'Inserm - Institut national de la santé et de la recherche médicale

2008 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Genetics/Molecular Biology and Cell Biology

1998 - Member of Academia Europaea

Member of the European Molecular Biology Organization (EMBO)

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • DNA
  • Gene expression

Ingrid Grummt mostly deals with Transcription, Molecular biology, RNA polymerase I, Transcription factor and General transcription factor. Transcription is a subfield of Genetics that she investigates. Her Molecular biology research is multidisciplinary, incorporating elements of Methylation, Promoter, Chromatin immunoprecipitation, Gene expression and DNA demethylation.

Her research integrates issues of RNA polymerase III, Transcriptional regulation and Cell biology in her study of RNA polymerase I. Her work deals with themes such as Cell cycle, Nucleolus and Protein kinase A, which intersect with Transcription factor. Her General transcription factor research incorporates themes from RNA polymerase II and Transcription factor II D.

Her most cited work include:

  • Mammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcription (447 citations)
  • Life on a planet of its own: regulation of RNA polymerase I transcription in the nucleolus (426 citations)
  • The Epigenetics of rRNA Genes: From Molecular to Chromosome Biology (392 citations)

What are the main themes of her work throughout her whole career to date?

Molecular biology, Transcription, RNA polymerase I, Cell biology and General transcription factor are her primary areas of study. Her Molecular biology research also works with subjects such as

  • Transcription factor together with Phosphorylation,
  • Ribosomal RNA which intersects with area such as Ribosome. Her Transcription research includes themes of RNA and DNA-binding protein.

The concepts of her RNA polymerase I study are interwoven with issues in RNA polymerase III, Nucleolus and Transcriptional regulation. Her studies deal with areas such as Ribosome biogenesis and Transcription preinitiation complex as well as Cell biology. Her study on General transcription factor also encompasses disciplines like

  • RNA polymerase II which connect with Transcription factor II D, RNA polymerase II holoenzyme and Transcription factories,
  • TAF2 which intersects with area such as Sp3 transcription factor.

She most often published in these fields:

  • Molecular biology (56.76%)
  • Transcription (45.41%)
  • RNA polymerase I (41.62%)

What were the highlights of her more recent work (between 2009-2020)?

  • Transcription (45.41%)
  • Genetics (26.49%)
  • Cell biology (30.81%)

In recent papers she was focusing on the following fields of study:

Ingrid Grummt mainly investigates Transcription, Genetics, Cell biology, RNA and Chromatin. Her study in the fields of RNA polymerase I under the domain of Transcription overlaps with other disciplines such as Growth factor. Her study in the field of Heterochromatin, Epigenetics of physical exercise, ChIA-PET and Chromosome conformation capture also crosses realms of Centromere.

Her Cell biology study also includes

  • Ribosome biogenesis together with SIRT7, General transcription factor, RNA polymerase II holoenzyme and Transcription factor II D,
  • Cell cycle checkpoint which intersects with area such as Mediator, Function and Phenotype. Her RNA research is multidisciplinary, incorporating perspectives in Enhancer and DNA. In her study, Epigenetics is strongly linked to Regulation of gene expression, which falls under the umbrella field of Chromatin.

Between 2009 and 2020, her most popular works were:

  • Interaction of noncoding RNA with the rDNA promoter mediates recruitment of DNMT3b and silencing of rRNA genes (365 citations)
  • PHF8 activates transcription of rRNA genes through H3K4me3 binding and H3K9me1/2 demethylation (172 citations)
  • Long Noncoding RNA TARID Directs Demethylation and Activation of the Tumor Suppressor TCF21 via GADD45A (168 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Gene expression

The scientist’s investigation covers issues in Genetics, Molecular biology, Transcription, Gene and Chromatin. Her research in Genetics is mostly concerned with Epigenetics of physical exercise. Her work carried out in the field of Molecular biology brings together such families of science as RNA, Non-coding RNA, Antisense RNA, Histone methyltransferase and RNA polymerase I.

Her Transcription research integrates issues from Nucleolus and DNA. Her Chromatin research incorporates themes from Regulation of gene expression and Transcription preinitiation complex. She has included themes like Ribosome biogenesis and Ribosome in her Cell biology study.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Mammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcription

Ethan Ford;Renate Voit;Gregory Liszt;Cornelia Magin.
Genes & Development (2006)

689 Citations

Life on a planet of its own: regulation of RNA polymerase I transcription in the nucleolus

Ingrid Grummt.
Genes & Development (2003)

662 Citations

Ribosome biogenesis and cell growth: mTOR coordinates transcription by all three classes of nuclear RNA polymerases

C Mayer;I Grummt.
Oncogene (2006)

588 Citations

mTOR-dependent activation of the transcription factor TIF-IA links rRNA synthesis to nutrient availability

Christine Mayer;Jian Zhao;Xuejun Yuan;Ingrid Grummt.
Genes & Development (2004)

562 Citations

Interaction of noncoding RNA with the rDNA promoter mediates recruitment of DNMT3b and silencing of rRNA genes

Kerstin Maike Schmitz;Christine Mayer;Anna Postepska;Ingrid Grummt.
Genes & Development (2010)

556 Citations

The Epigenetics of rRNA Genes: From Molecular to Chromosome Biology

Brian McStay;Ingrid Grummt.
Annual Review of Cell and Developmental Biology (2008)

510 Citations

c-Myc associates with ribosomal DNA and activates RNA polymerase I transcription.

Azadeh Arabi;Azadeh Arabi;Siqin Wu;Karin Ridderstråle;Holger Bierhoff.
Nature Cell Biology (2005)

497 Citations

A Kinetic Framework for a Mammalian RNA Polymerase in Vivo

Miroslav Dundr;Urs Hoffmann-Rohrer;Qiyue Hu;Ingrid Grummt.
Science (2002)

479 Citations

The nucleolar remodeling complex NoRC mediates heterochromatin formation and silencing of ribosomal gene transcription

Raffaella Santoro;Junwei Li;Ingrid Grummt.
Nature Genetics (2002)

452 Citations

Nuclear actin and myosin I are required for RNA polymerase I transcription

Vlada V. Philimonenko;Jian Zhao;Sebastian Iben;Hana Dingová.
Nature Cell Biology (2004)

431 Citations

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