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Genetics and Molecular Biology
Germany
2024

D-Index & Metrics

Molecular Biology

D-Index
106
Citations
30224
World Ranking
436
National Ranking
38

Research.com Recognitions

  • 2024 - Research.com Genetics and Molecular Biology in Germany Leader Award
  • 2012 - Grand prix de l'Inserm - Institut national de la santé et de la recherche médicale
  • 2008 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Genetics/Molecular Biology and Cell Biology
  • 1998 - Member of Academia Europaea
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Ingrid Grummt is affiliated with the German Cancer Research Center in Germany. Their research primarily centers on biochemistry, genetics, and molecular biology, with a particular focus on molecular biology.

The scientist's work encompasses several specialized subfields, including cancer research, biological psychiatry, neurology, and immunology. Key topics covered in their research involve RNA modifications and cancer, RNA research and splicing, cancer-related molecular mechanisms, tryptophan and brain disorders, neuroinflammation and neurodegeneration mechanisms, immune cells in cancer, and the mechanisms of RNA and protein synthesis.

Frequent co-authors in Ingrid Grummt's publications include Matthias S. Leisegang, Jasleen Kaur Bains, Sandra Seredinski, James A. Oo, and Nina Krause.

Recent papers authored or co-authored by Ingrid Grummt include the following:

  • HIF1α-AS1 is a DNA:DNA:RNA triplex-forming lncRNA interacting with the HUSH complex, 2022, Nature Communications
  • Constitutive Expression of the Immunosuppressive Tryptophan Dioxygenase TDO2 in Glioblastoma Is Driven by the Transcription Factor C/EBPβ, 2020, Frontiers in Immunology
  • Analysis of RNA-DNA Triplex Structures In Vitro and In Vivo, 2020, Methods in Molecular Biology
  • HIF1α-AS1 is a DNA:DNA:RNA triplex-forming lncRNA interacting with the HUSH complex, 2021, bioRxiv (Cold Spring Harbor Laboratory)

These publications have appeared in venues such as Nature Communications, Frontiers in Immunology, Methods in Molecular Biology, and bioRxiv (Cold Spring Harbor Laboratory).

Ingrid Grummt has been recognized through several awards and memberships. These include membership in the European Molecular Biology Organization (EMBO), membership of the Academia Europaea, affiliation with the German National Academy of Sciences Leopoldina under the categories Genetics/Molecular Biology and Cell Biology, and receipt of the Grand prix de l'Inserm - Institut national de la santé et de la recherche médicale in 2012.

Best Publications

  • Mammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcription

    Ethan Ford;Renate Voit;Gregory Liszt;Cornelia Magin

  • Ribosome biogenesis and cell growth: mTOR coordinates transcription by all three classes of nuclear RNA polymerases

    C Mayer;I Grummt

  • Life on a planet of its own: regulation of RNA polymerase I transcription in the nucleolus

    Ingrid Grummt

  • mTOR-dependent activation of the transcription factor TIF-IA links rRNA synthesis to nutrient availability

    Christine Mayer;Jian Zhao;Xuejun Yuan;Ingrid Grummt

  • Interaction of noncoding RNA with the rDNA promoter mediates recruitment of DNMT3b and silencing of rRNA genes

    Kerstin Maike Schmitz;Christine Mayer;Anna Postepska;Ingrid Grummt

  • The Epigenetics of rRNA Genes: From Molecular to Chromosome Biology

    Brian McStay;Ingrid Grummt

  • c-Myc associates with ribosomal DNA and activates RNA polymerase I transcription.

    Azadeh Arabi;Azadeh Arabi;Siqin Wu;Karin Ridderstråle;Holger Bierhoff

  • A Kinetic Framework for a Mammalian RNA Polymerase in Vivo

    Miroslav Dundr;Urs Hoffmann-Rohrer;Qiyue Hu;Ingrid Grummt

  • The nucleolar remodeling complex NoRC mediates heterochromatin formation and silencing of ribosomal gene transcription

    Raffaella Santoro;Junwei Li;Ingrid Grummt

  • Nuclear actin and myosin I are required for RNA polymerase I transcription

    Vlada V. Philimonenko;Jian Zhao;Sebastian Iben;Hana Dingová

  • Intergenic transcripts regulate the epigenetic state of rRNA genes.

    Christine Mayer;Kerstin Maike Schmitz;Junwei Li;Ingrid Grummt

  • NoRC--a novel member of mammalian ISWI-containing chromatin remodeling machines.

    Ralf Strohner;Attila Nemeth;Petr Jansa;Urs Hofmann-Rohrer

  • ERK-Dependent Phosphorylation of the Transcription Initiation Factor TIF-IA Is Required for RNA Polymerase I Transcription and Cell Growth

    Jian Zhao;Xuejun Yuan;Morten Frödin;Ingrid Grummt

  • Regulation of mammalian ribosomal gene transcription by RNA polymerase I.

    Ingrid Grummt

  • Cellular Stress and Nucleolar Function

    Christine Mayer;Ingrid Grummt

  • Long Noncoding RNA TARID Directs Demethylation and Activation of the Tumor Suppressor TCF21 via GADD45A

    Khelifa Arab;Yoon Jung Park;Anders M. Lindroth;Andrea Schäfer

  • Epigenetic silencing of RNA polymerase I transcription

    Ingrid Grummt;Craig S. Pikaard

  • The nucleolus as a stress sensor: JNK2 inactivates the transcription factor TIF-IA and down-regulates rRNA synthesis

    Christine Mayer;Holger Bierhoff;Ingrid Grummt

  • Molecular Mechanisms Mediating Methylation-Dependent Silencing of Ribosomal Gene Transcription

    Raffaella Santoro;Ingrid Grummt

  • The chromatin remodeling complex NoRC targets HDAC1 to the ribosomal gene promoter and represses RNA polymerase I transcription

    Yonggang Zhou;Raffaella Santoro;Ingrid Grummt

Frequent Co-Authors

Gernot Längst
Gernot Längst University of Regensburg
Martin Vingron
Martin Vingron Max Planck Society
Günther Schütz
Günther Schütz German Cancer Research Center
Craig Horbinski
Craig Horbinski Northwestern University
Atsuo T. Sasaki
Atsuo T. Sasaki University of Cincinnati
Tomoyoshi Soga
Tomoyoshi Soga Keio University
Hanswalter Zentgraf
Hanswalter Zentgraf German Cancer Research Center
Michael Rehli
Michael Rehli University of Regensburg
Petra Boukamp
Petra Boukamp German Cancer Research Center
Hendrik G. Stunnenberg
Hendrik G. Stunnenberg Radboud University

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